[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551123":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":38,"locations":45,"responsibleParty":60,"collaborators":31,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":28,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":31,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":31,"overallStatus":48,"whyStopped":31,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"The University of Tennessee, Knoxville","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"DEPTH-Standard","ACTIVE_COMPARATOR","Participants in the Standard Group will receive a reduced-energy, low-fat dietary prescription (1200-1500 kcal\u002Fd, \\\u003C 30% energy from fat), physical activity goals (\\> 200 min\u002Fwk of moderate- to vigorous-intensity physical activity \\[MVPA\\]) and a cognitive behavioral intervention. Standard group will receive no guidance on energy intake distribution (standard lifestyle intervention).",[13],"Behavioral: DEPTH",{"label":15,"type":16,"description":17,"interventionNames":18},"DEPTH-Morning","EXPERIMENTAL","Participants in the Morning Group will receive a reduced-energy, low-fat dietary prescription (1200-1500 kcal\u002Fd, \\\u003C 30% energy from fat), physical activity goals (\\> 200 min\u002Fwk of moderate- to vigorous-intensity physical activity \\[MVPA\\]) and a cognitive behavioral intervention. They will also have time-based energy intake goals of 70% of kcal within the first 6 hrs of the eating window and 30% of kcal within the last 6 hrs of the eating window (a morning-loaded energy distribution).",[13,19],"Behavioral: DEPTH-Morning",{"label":21,"type":16,"description":22,"interventionNames":23},"DEPTH-Evening","Participants in the Evening Group will receive a reduced-energy, low-fat dietary prescription (1200-1500 kcal\u002Fd, \\\u003C 30% energy from fat), physical activity goals (\\> 200 min\u002Fwk of moderate- to vigorous-intensity physical activity \\[MVPA\\]) and a cognitive behavioral intervention. They will also have time-based energy intake goals of 30% of kcal within the first 6 hrs of the eating window and 70% of kcal within the last 6 hrs of the eating window (an evening-loaded energy distribution).",[13,24],"Behavioral: DEPTH-Evening",[26,32,35],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"BEHAVIORAL","DEPTH","All conditions will receive a reduced-energy, low-fat dietary prescription (1200-1500 kcal\u002Fd, \\\u003C 30% energy from fat), physical activity goals (\\> 200 min\u002Fwk of moderate- to vigorous-intensity physical activity \\[MVPA\\]) and a cognitive behavioral intervention. To minimize the effect of other eating temporal variables on outcomes, guidance on the eating window length and the number of eating occasions in the day will be consistent across all three conditions. Thus, the three conditions will be instructed to have their first eating occasion \\\u003C 60 minutes of awakening, and eat their three meals and one snack within a 12-hr eating window.",[21,15,9],null,{"type":27,"name":15,"description":33,"armGroupLabels":34,"otherNames":31},"Morning will also have time-based energy intake goals of 70% of kcal within the first 6 hrs of the eating window and 30% of kcal within the last 6 hrs of the eating window (a morning-loaded energy distribution).",[15],{"type":27,"name":21,"description":36,"armGroupLabels":37,"otherNames":31},"Evening will also have time-based energy intake goals of 30% of kcal within the first 6 hrs of the eating window and 70% of kcal within the last 6 hrs of the eating window (an evening-loaded energy distribution).",[21],[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Hollie A Raynor, PhD","CONTACT","865-974-9126","1","hraynor@utk.edu",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":31},"Healthy Eating and Activity Laboratory","RECRUITING","Knoxville","Tennessee","37996","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-83.92074,35.96064,{"lat":58,"lon":57},{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Hollie Raynor","Executive Associate Dean of Research & Operations, College of Education, Health, and Human Sciences","100551123","daily-eating-patterns-for-total-health-study-100551123",false,"NCT06455995","Daily Eating Patterns for Total Health Study","Effect of Time-based Energy Intake Goals on Weight Loss During Obesity Treatment","Inclusion Criteria:\n\n* Body mass index (BMI) between 27 and 45 kg\u002Fm2.\n\nExclusion Criteria:\n\n* Report not regularly (\\>\u002F= 5 days\u002Fwk) consuming energy (\\>\u002F= 100 kcal) prior to 12 pm, and not being able to consume energy every day (\\>\u002F= 50 kcal) within one hour of awakening.\n* Report taking sleep medication or not regularly (\\>\u002F= 5 nights\u002Fwk) getting at least 6 hrs of total sleep.\n* Report being a shift workers\u002Falternative shift workers that work outside of 7 am and 7 pm.\n* Report being diagnosed with type 1, or type 2 diabetes and taking medication that requires eating to occur at certain time periods.\n* Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q). Individuals reporting joint problems, prescription medication usage, or other medical conditions that could limit exercise will be required to obtain written physician consent to participate.\n* Report being unable to walk for 2 blocks (1\u002F4 mile) without stopping.\n* Report major psychiatric diseases or organic brain syndromes.\n* Report currently participating in a weight loss program and\u002For taking weight loss or appetite regulation medication or lost \\>\u002F= 5% of body weight during the past 6 months.\n* Report having bariatric surgery for weight loss\u002Fplanning to have bariatric surgery in the next 12 months.\n* Report being pregnant, lactating, \\\u003C 6 months post-partum or plan to become pregnant (next 12 months).\n* Report planning to move outside of the metropolitan area within the time frame of the investigation.\n* Do not have daily access to PC with internet or smartphones (needed for self-monitoring).","ALL","25 Years","60 Years",{"count":75,"type":76},174,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss in the long-term (12 months). The main aims are to learn:\n\n1. The influence of time-based energy intake goals on longer-term weight loss.\n2. The influence of time-based energy intake goals on eating temporal patterns, sleep regularity, and appetite regulation.\n\nResearchers will compare whether goals to eat most of a person's calories in the morning or evening work to treat obesity.\n\nParticipants will:\n\n1. Eat a reduced-calorie, low-fat diet (some participants will have goals to eat their calories at certain times of day based on their group)\n2. Be physically active at least 200 minutes\n3. Receive a cognitive behavioral intervention",[82],"Obesity","2026-06-12",{"date":85,"type":86},"2026-06-15","ACTUAL",{"date":88,"type":86},"2024-07-16",{"date":90,"type":76},"2028-12",{"name":5,"class":6},1]