[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622594":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":51,"collaborators":54,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":18,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":18,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Vanderbilt University Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"10˚C deceased donor kidney storage","EXPERIMENTAL","Deceased donor kidneys from participating organ procurement organizations (OPO) will be procured per OPO routine clinical practice and then stored at 10˚C in dedicated temperature controlled coolers until transplant at Vanderbilt University Medical Center. Donor kidneys will be labeled with the anonymous United Network for Organ Sharing number. The transplant will then proceed per routine clinical practice and usual clinical pathways will be followed. Post operatively, study participants will have their urine collected 24 hours post operatively and analyzed. Routine clinical information will be abstracted from the electronic medical record and used for analysis.",[13],"Device: 10˚C deceased donor kidney storage using Traferox XPort",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional (ice storage) deceased donor kidney storage","NO_INTERVENTION","Deceased donor kidneys, not meeting eligibility for the intervention arm, that are accepted for transplant at Vanderbilt University Medical Center will be procured per routine clinical practice and stored conventionally on ice. Donor kidneys will be labeled with the anonymous United Network for Organ Sharing number. The transplant will proceed per routine clinical practice. Usual clinical pathways will be followed. Post operatively, study participants will have their urine collected 24 hours post operatively and analyzed. Routine clinical information will be abstracted from the electronic medical record and used for analysis.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","10˚C deceased donor kidney storage using Traferox XPort","Deceased donor kidneys will be stored using the Traferox XPort device to maintain an organ temperature of 10˚C during storage and transport until the time of transplant",[9],[26],{"name":27,"affiliation":5,"role":28},"W. Christian Crannell, MD","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},"CONTACT","615-322-5000","christian.crannell@vumc.org",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Nashville","Tennessee","37027","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-86.78444,36.16589,{"lat":46,"lon":45},[49,50],{"name":27,"role":31,"phone":32,"phoneExt":18,"email":33},{"name":27,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":28,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Christian Crannell","Assistant Professor of Surgery",[55],{"name":56,"class":57},"Traferox Technology Inc.","UNKNOWN","100622594","deceased-donor-kidney-storage-at-10-celsius-versus-conventional-storage-100622594",false,"NCT07385651","Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage","Participant inclusion criteria\n\n1\\. All adult single organ kidney transplant candidates on the waiting list at Vanderbilt University Medical Center (VUMC) will be eligible for enrollment.\n\nParticipant exclusion criteria\n\n1. Kidney transplant candidates less than 18 years old\n2. Kidney transplant candidates that decline consent\n3. Transplant candidates listed for multi-organ transplant\n\nDeceased donor organ inclusion criteria:\n\n1. Donation after brain death or donation after circulatory death kidney donors, whose health care proxy has consented for donation and the possibility of research\n2. Deceased donor kidneys that have been allocated to VUMC as a primary match offer prior to organ procurement will be eligible\n\nDeceased donor organ exclusion criteria:\n\n1. Donors whose health care proxy has declined consent for the possibility of research\n2. Deceased donor kidneys that have been allocated to VUMC as a backup offer\n3. Deceased donor kidneys that have been allocated to VUMC as a post procurement offer\n4. Deceased donor kidneys that have already been placed on ice","ALL","18 Years",{"count":67,"type":68},30,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this clinical trial is to test how storage temperature of deceased donor kidneys affects kidney function after transplant in adult patients receiving a kidney transplant.\n\nThe main question it aims to answer is:\n\n• Do patients that receive a kidney transplant stored at 10 °C have improved post-transplant kidney function? Researchers will compare patients who receive kidneys stored at 10 °C versus kidneys stored at 4°C (on ice, i.e. conventional storage) to see if kidneys stored at 10 °C have improved function.\n\nParticipants will:\n\n* Be made aware of and consent to receive a kidney transplant that had been stored at 10 °C\n* Have their urine collected 24 hours after surgery to be analyzed for research",[74,75,76],"End Stage Chronic Renal Failure","Chronic Kidney Disease (Stages 4 and 5)","Kidney Transplantation Recipients",[78,79,80,81],"kidney transplant recipients","delayed graft function","ischemia reperfusion injury","10 Celsius kidney storage","2026-04-03",{"date":84,"type":85},"2026-04-06","ACTUAL",{"date":87,"type":85},"2024-11-18",{"date":89,"type":68},"2027-12",{"name":5,"class":6},1]