[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633738":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":73,"collaborators":75,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":93,"sex":99,"minAge":100,"maxAge":18,"enrollmentInfo":101,"targetDuration":18,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":45,"whyStopped":18,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"University Hospital of North Norway","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","Participants are patients presenting with acute stroke symptoms in rural districts in Norway. A cockpit solution by Syngo Virtual Cockpit® software for remote control of the stationary CT machine at the DMCs from the nearest stroke center is implemented. The EMC center routes the ambulance to DMC Midt-Troms when it is the nearest. A nurse at DMC and the ambulance personnel performs the clinical examination and positions the patient in the CT machine. Through AVC the examination is overseen by the stroke physician, images are interpreted by a radiologist at UNN, and the decision regarding acute treatment is made by the stroke physician at UNN, Tromsø. If indicated, IVT and blood pressure lowering medication is administered by the nurse at the DMC. Patients resenting with acute stroke symptoms in the catchment area of DMC Midt-Troms (Sørreisa and Senja municipalities) and DMC Sør-Helgeland (Brønnøy and Sømna municipalities) comprise the intervention group.",[13],"Other: Decentralized diagnostics and treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","1\\) Patients presenting with acute stroke symptoms residing in municipalities in Nord-Troms (Nordreisa, Kåfjord, Skjervøy and Kvænangen) and Nordland (Saltdal, Hamarøy, Steigen and Sørfold) from the time of DMC model implementation until end of study. These patients are from areas that are geographically similar to Midt-Troms and Sør-Helgeland with regards to distance to the nearest hospital, but without access to prehospital CT diagnostics and acute stroke treatment.",null,{"label":20,"type":16,"description":21,"interventionNames":18},"Historical control","This control group consists of acute stroke patients from the same municipalities (both intervention and control group) presenting with stroke symptoms within a 5 year period prior to the implementation of prehospital diagnostics and treatment at the DMC.",[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Decentralized diagnostics and treatment","The intervention includes admittance to the DMC for initial diagnostic work up and acute treatment (if indicated). Paramedics examine the patient and assess stroke severity by NIHSS and G-FAST scoring overseen by a stroke physician at the local hospital through real time video conference. A remote controlled CT scan of the head is conducted, and the stroke team at the local hospital evaluates results and makes a treatment decision in real-time AVC. If treatment is indicated, this is administered by local personnel at the DMC before initiating transport to the local hospital or the comprehensive stroke center in case of LVO. Patients who are unable to reach the DMC prior to estimated admission time at their local hospital, will be treated at their local hospital as per standard pathway.",[9],[28],"Prehospital diagnostics and treatment",[30],{"name":31,"affiliation":5,"role":32},"Tor Ingebrigtsen, MD, PhD","STUDY_DIRECTOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":18,"email":38},"Agnethe Eltoft, MD, PhD","CONTACT","+4797193417","agnethe.eltoft@unn.no",{"name":40,"role":36,"phone":18,"phoneExt":18,"email":41},"Eivor Logstein, MD","Eivor.Logstein@Helgelandssykehuset.no",[43,60],{"facility":44,"status":45,"city":46,"state":18,"zip":18,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Helgelandssykehuset Health Trust","RECRUITING","Sandnessjøen","Norway","NO",{"type":50,"coordinates":51},"Point",[52,53],12.63158,66.02166,{"lat":53,"lon":52},[56,57],{"name":40,"role":36,"phone":18,"phoneExt":18,"email":41},{"name":58,"role":36,"phone":18,"phoneExt":18,"email":59},"Jon Våbenø, PhD","Jon.Vabeno@Helgelandssykehuset.no",{"facility":61,"status":45,"city":62,"state":18,"zip":18,"country":47,"countryCode":48,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"University Hospital of North Norway Health Trust","Tromsø",{"type":50,"coordinates":64},[65,66],18.95508,69.6489,{"lat":66,"lon":65},[69,71],{"name":70,"role":36,"phone":18,"phoneExt":18,"email":38},"Agnethe Eltoft, MR, PhD",{"name":31,"role":36,"phone":18,"phoneExt":18,"email":72},"Tor.Ingebrigtsen@unn.no",{"type":74,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[76,79,81,83,85,87,89],{"name":77,"class":78},"Helgelandssykehuset Hospital Trust","UNKNOWN",{"name":80,"class":78},"Nordlandssykehuset Hospital Trust",{"name":82,"class":78},"Finnmarkssykehuset HF",{"name":84,"class":6},"UiT The Arctic University of Norway",{"name":86,"class":78},"Innlandet Central Hospital HF, Lillehammer",{"name":88,"class":6},"Oslo University Hospital",{"name":90,"class":78},"Ringerike hospital HF, Hønefoss Norway","100633738","decentralized-imaging-by-remote-computer-tomography-for-cerebral-infarct-thrombolysis-100633738",false,"NCT07530588","Decentralized Imaging by REmote Computer Tomography for Cerebral Infarct Thrombolysis","Remote Controlled CT Scanning for Decentralized Diagnostics and Treatment Versus Standard Care in Acute Stroke","DIRECT-CT","Inclusion Criteria:\n\n\\- Patients in the catchments areas of the intervention and control group presenting with a clinical suspected diagnosis of stroke within symptom onset within the last 24 hours\n\nExclusion Criteria:\n\n\\- Patients presenting with a clinical suspected diagnosis of stroke more than 24 hours after symptom onset","ALL","18 Years",{"count":102,"type":103},52,"ESTIMATED","INTERVENTIONAL",[106],"NA","The DIRECT-CT trial is designed to test the hypothesis that remote controlled CT scanning combined with real time audio-and video conference (AVC) guided assessment from an experienced hospital stroke team (tele-stroke) at decentralized medical centers (DMC) reduces time to intravenous thrombolytic treatment compared to the standard pathway.",[109],"Stroke",[109,111,28,112,113,114],"Rural","Remote controlled computer tomography","Intravenous thrombolysis","District medical center","2026-04-10",{"date":117,"type":118},"2026-04-15","ACTUAL",{"date":120,"type":118},"2025-07-17",{"date":122,"type":103},"2028-12-31",{"name":5,"class":6},2]