[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595165":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":41,"centralContacts":52,"locations":57,"responsibleParty":63,"collaborators":57,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":57,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":57,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":57,"overallStatus":86,"whyStopped":57,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":57},{"fullName":5,"class":6},"Minia University","OTHER",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Total caries removal in primary caries","ACTIVE_COMPARATOR","Total caries removal Removal of all caries and application of bioactive material",[13],"Procedure: Total caries removal",{"label":15,"type":10,"description":16,"interventionNames":17},"Total caries removal of secondary caries","Total caries removal of caries of recurrent caries",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Partial caries removal of primary caries","Partial caries removal and application of bioactive material",[22],"Procedure: Partial caries removal",{"label":24,"type":10,"description":25,"interventionNames":26},"Partial caries removal of secondary caries","Partical caries removal of recurrent caries",[22],[28,35],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"PROCEDURE","Total caries removal","Total caries removal and application of bioactive material",[9,15],[34],"Biodentin application",{"type":29,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Partial caries removal","Partial caries removal then application of biodentin",[19,24],[40],"Biodentin",[42,45,48,50],{"name":43,"affiliation":5,"role":44},"Abeer Mohmaed Shehata, Master","PRINCIPAL_INVESTIGATOR",{"name":46,"affiliation":5,"role":47},"Rasha Saad, lecturer","STUDY_DIRECTOR",{"name":49,"affiliation":5,"role":47},"Mohammed Torky, Associate professor",{"name":51,"affiliation":5,"role":47},"Nermin Mahmoud, Associate professor",[53,59],{"name":54,"role":55,"phone":56,"phoneExt":57,"email":58},"Abeer M. Shehata, MASTER","CONTACT","00201094238606",null,"abeer.shehata@mu.edu.eg",{"name":60,"role":55,"phone":61,"phoneExt":57,"email":62},"Abeer M. Shehata, master","00201094830487","abeermasr@hotmail.com",{"type":44,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":57,"oldOrganization":57},"Abeer mohamed shehata","Abeer Mohamed Shehata","100595165","deep-caries-in-mature-teeth-with-reversible-pulpitis-100595165",false,"NCT07028905","Deep Caries in Mature Teeth With Reversible Pulpitis","Clinical, Radiographical, and Histological Evaluation of Treatment Outcomes Following Different Caries Removal Strategies in Mature Permanent Teeth With Reversible Pulpitis (A Randomized Clinical Trial and Ex-vivo Study)","Inclusion Criteria:\n\n1. The patient's age from 18 years to 40 years old\n2. Non -contributory medical history (ASA1)\n3. Mature permanent posterior teeth with primary or secondary deep caries extending ≥ 2\u002F3 of dentin\n4. The tooth should give a positive response to cold testing\n5. Clinical diagnosis of reversible pulpitis\n6. The tooth is restorable via direct restoration, probing pocket depth and mobility are within normal limits\n7. No signs of pulpal necrosis including sinus tract or swelling\n8. No radiographic evidence of periapical changes indicative of apical periodontitis\n\nExclusion Criteria:\n\n* Systemic medical conditions, pregnancy, alcoholic and smoker patients. 2- Teeth with spontaneous pain or percussion sensitivity in periodontal lesions, external or internal root resorption, sinus opening, mobility, or abscessed tooth. 3- Radiographic evidence of widened periodontal space, broken or interrupted lamina dura, and periapical radiolucency. 4- Intensified erosion damage or periodontitis. Patient reported clenching or bruxism, hopeless or non-restorable teeth. Immature teeth. 5- Patients with physical disabilities preventing tooth brushing. Patient had removable partial denture abutments, dental abscesses, pulp lesions, atypical facial pain, or pulpitis. 6- Patients had non-carious lesions like abrasion, erosion, attrition, or abfraction.\n\n  7- Patients with history of antibiotic or analgesics intake within few days of operative intervention. 8- Patients with previously root canal-treated teeth. 9- Periodontally compromised teeth. 10-Teeth that will be extracted for periodontal or orthodontic reasons as it will conduct for histological evaluation",true,"ALL","18 Years","40 Years",{"count":78,"type":79},144,"ESTIMATED","INTERVENTIONAL",[82],"NA","This clinical trial will be conducted to clinical, radiographical and histological evaluation of pulp condition with reversible pulpities after total and selective removal of primary and secondary caries (randomized clinical trial and exo-vivo study)",[85],"Deep Caries","NOT_YET_RECRUITING","2025-09-22",{"date":89,"type":90},"2025-09-26","ACTUAL",{"date":92,"type":79},"2025-10-20",{"date":94,"type":79},"2026-12-01",{"name":5,"class":6}]