[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604990":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":52,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":19,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":19,"overallStatus":28,"whyStopped":19,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Tanta University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Deep Marginal Elevation (DME)","EXPERIMENTAL","Participants with Class II dental caries will receive Deep Marginal Elevation (DME) using resin-modified glass ionomer cement (RMGIC) followed by adhesive and nano filled composite restoration.",[13],"Procedure: Deep Marginal Elevation (DME)",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Deep Marginal Elevation (DME) is performed by elevating the deep margin of Class II cavities using resin-modified glass ionomer cement (RMGIC), followed by adhesive bonding and placement of a nanofilled composite resin restoration. This procedure improves accessibility of the restorative margin, enhances marginal sealing, and facilitates plaque control.",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Mohamed O Elboraey, MD","CONTACT","00201062250015","mohamedomarelboraey@gmail.com",[27],{"facility":5,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Tanta","El-Gharbia","31527","Egypt","EG",{"type":35,"coordinates":36},"Point",[37,38],31.00192,30.78847,{"lat":38,"lon":37},[41,43,46,48,50],{"name":22,"role":23,"phone":42,"phoneExt":19,"email":25},"0021062250015",{"name":44,"role":45,"phone":19,"phoneExt":19,"email":19},"Laila T Kashkosh, MD","PRINCIPAL_INVESTIGATOR",{"name":47,"role":45,"phone":19,"phoneExt":19,"email":19},"Mostafa I Fayad, MD",{"name":49,"role":45,"phone":19,"phoneExt":19,"email":19},"Sherouk M Gamal, MD",{"name":51,"role":45,"phone":19,"phoneExt":19,"email":19},"Mohammed A Abd El Ghany, MD",{"type":45,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Mohamed Omar Elboraey Elbal","Assistant Professor of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology Department, Faculty of Dentistry, Tanta, University, Tanta, Egypt.","100604990","deep-marginal-elevation-and-the-periodontal-microenvironment--dme-pm--100604990",false,"NCT07156695","Deep Marginal Elevation and the Periodontal Microenvironment ( DME-PM )","Deep Marginal Elevation and Its Impact on Periodontal Microenvironment: Microbiological, Clinical, and Radiographic Study","Inclusion Criteria:\n\n* Patients aged 18-60 years.\n* Diagnosed with Class II dental caries requiring restoration.\n* Presence of a healthy contralateral tooth (control side).\n* Willingness to participate and comply with follow-up visits.\n\nExclusion Criteria:\n\n* Systemic diseases (e.g., diabetes, autoimmune disorders).\n* Periodontal disease or active infection.\n* Use of anti-inflammatory medications within the last month.\n* Pregnancy or lactation.","ALL","18 Years","60 Years",{"count":66,"type":67},36,"ESTIMATED","INTERVENTIONAL",[70],"NA","This study aims to evaluate the impact of the dental restorative procedure known as Deep Marginal Elevation (DME) on periodontal health, including gingival and bone status, in patients with deep dental caries. Gingival fluid samples will be collected, and radiographic assessments will be performed to monitor changes in inflammation and bone levels. The findings are expected to provide insights into how DME influences gingival and bone health.",[73,74,75,76,77],"Deep Marginal Elevation","Periodontal Microenvironment","Microbiological Study","Clinical Study","Radiographic Study","2025-09-03",{"date":80,"type":81},"2025-09-05","ACTUAL",{"date":83,"type":81},"2025-08-01",{"date":85,"type":67},"2026-01-01",{"name":5,"class":6},1]