[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571643":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":14,"collaborators":7,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":7,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":7,"enrollmentInfo":25,"targetDuration":7,"studyType":28,"phases":7,"briefSummary":29,"conditions":30,"keywords":35,"overallStatus":37,"whyStopped":7,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":7},{"fullName":5,"class":6},"Uppsala University","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Mikael Eriksson, MD, PhD","CONTACT","+46186110000","mikael.e.eriksson@uu.se",{"type":15,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100571643","definition-of-acute-kidney-injury-by-urine-output-in-critically-ill-patients-100571643",false,"NCT06722924","Definition of Acute Kidney Injury by Urine Output in Critically Ill Patients","Definition of Acute Kidney Injury Based on Urine Output","Inclusion Criteria:\n\n* Admittance to intensive care units at Uppsala University Hospital between 2016-2024\n\nExclusion Criteria:\n\n* Minimum age 18 years","ALL","18 Years",{"count":26,"type":27},15000,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to explore the association between urine output and acute kidney injury in severely ill patients admitted to intensive care units. The main research questions are:\n\nWhat is the optimal threshold for defining reduced urine output in critically ill patients in intensive care? Is this threshold the same for different outcomes such as acute kidney injury, chronic kidney dysfunction, or mortality? Does this threshold change with treatment involving diuretics or dialysis? Does the patient's fluid balance or the amount of administered fluid affect the association between reduced urine output and the outcomes mentioned above? Is the optimal threshold for defining reduced urine output different for various patient categories and diagnoses, such as sepsis, burn injuries, or ARDS? Are there differences between surgical and non-surgical patients regarding the optimal threshold for defining reduced urine output in intensive care? Does the patient's comorbidity influence the level of reduced urine output that should be considered pathological?",[31,32,33,34],"Acute Kidney Injury","Critical Illness","Critical Care, Intensive Care","Critical Care, Fluid Resuscitation",[36],"observational study","NOT_YET_RECRUITING","2024-12-03",{"date":40,"type":41},"2024-12-09","ACTUAL",{"date":43,"type":27},"2024-12",{"date":45,"type":27},"2025-03",{"name":5,"class":6}]