[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618183":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":52,"collaborators":25,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":25,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":25,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":25,"overallStatus":74,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Rambam Health Care Campus","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Surveillance Group","ACTIVE_COMPARATOR","Participants undergo colonoscopy at 6, 18, and 48 months after piecemeal EMR.",[13],"Procedure: Colonoscopy after bowel cleansing",{"label":15,"type":16,"description":17,"interventionNames":18},"Relaxed Surveillance Group","EXPERIMENTAL","Participants undergo colonoscopy at 12 and 48 months after piecemeal EMR.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Colonoscopy after bowel cleansing","The procedure is performed by experienced endoscopists using high-definition white light and narrow-band imaging to carefully inspect the colon and assess the resection site. Biopsies are taken only if abnormal tissue or recurrence is suspected.",[15,9],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Klein","CONTACT","+972-4-7773625","am_klein@rmc.gov.il",[33],{"facility":34,"status":25,"city":35,"state":25,"zip":25,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Rambam Medical Center","Haifa","Israel","IL",{"type":39,"coordinates":40},"Point",[41,42],34.99928,32.81303,{"lat":42,"lon":41},[45,46,49],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},{"name":47,"role":48,"phone":25,"phoneExt":25,"email":25},"Klein, MD","PRINCIPAL_INVESTIGATOR",{"name":50,"role":51,"phone":25,"phoneExt":25,"email":25},"Falah, MD","SUB_INVESTIGATOR",{"type":48,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Amir Klein MD","Principal Investigator","100618183","delayed-surveillance-colonoscopy-following-piecemeal-emr-100618183",false,"NCT07328308","Delayed Surveillance Colonoscopy Following Piecemeal EMR","Delayed Surveillance Colonoscopy Following Piecemeal EMR - a Randomized Study","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Undergoing pEMR of LNPCPs\n* Able to provide informed consent and comply with follow-up requirements\n\nExclusion Criteria:\n\n* Patients with invasive cancer identified during the index procedure\n* en bloc resection\n* Patients unable to attend follow-up colonoscopies due to comorbid conditions\n* Patients who require additional surgery for polyp removal or other complications","ALL","18 Years",{"count":65,"type":66},760,"ESTIMATED","INTERVENTIONAL",[69],"NA","This multicenter, prospective, randomized non inferiority trial, conducted at four Israeli hospitals, will evaluate whether a relaxed surveillance strategy after piecemeal endoscopic mucosal resection (pEMR) of large non pedunculated colorectal polyps (LNPCPs, ≥20 mm) is as safe and effective as the current standard intensive surveillance. Approximately 760 adults undergoing complete pEMR with margin ablation will be randomized 1:1 into:\n\nStandard Surveillance: Colonoscopy at 6, 18, and 48 months\n\nRelaxed Surveillance: Colonoscopy at 12 and 48 months\n\nAll colonoscopies will be performed using high definition white light and narrow band imaging, with biopsies obtained only if recurrence is suspected. The investigators hypothesize that a relaxed surveillance strategy will be non inferior to the current standard intensive surveillance. If non inferiority is demonstrated, the study may support guideline changes toward reduced surveillance frequency after pEMR with margin ablation, potentially decreasing patient burden and healthcare costs.",[72,73],"Colon Cancer Prevention","Polyp Colorectal","NOT_YET_RECRUITING","2026-01-03",{"date":77,"type":78},"2026-01-09","ACTUAL",{"date":80,"type":66},"2026-01",{"date":82,"type":66},"2031-01",{"name":5,"class":6},1]