[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053679":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":62,"collaborators":24,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":24,"enrollmentInfo":75,"targetDuration":24,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":91,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Faculty of Medicine of Tunis","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Delayed Umbilical Cord Clamping","EXPERIMENTAL","Delayed umbilical cord clamping is performed in preterm infants according to the study protocol. The umbilical cord is clamped after a predefined delay following birth (at least 30 seconds), allowing continued placental transfusion to the neonate before cord clamping. The intervention is applied immediately after delivery while ensuring neonatal stabilization according to standard clinical practice.",[13],"Procedure: Delayed Umbilical Cord Clamping",{"label":15,"type":10,"description":16,"interventionNames":17},"Immediate Umbilical Cord Clamping","Immediate umbilical cord clamping is performed in preterm infants according to standard practice. The umbilical cord is clamped shortly after birth without intentional delay, typically within seconds of delivery, before significant placental transfusion occurs. Neonatal care is provided immediately after clamping according to routine clinical protocols.",[18],"Procedure: Immediate Umbilical Cord Clamping",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Delayed umbilical cord clamping is performed in preterm infants by delaying umbilical cord clamping for a predefined duration after birth (at least 30 seconds), allowing continued placental transfusion prior to neonatal separation from the placenta. The procedure is applied immediately after delivery, with neonatal stabilization provided according to standard clinical practice.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Immediate umbilical cord clamping is performed in preterm infants by clamping the umbilical cord shortly after birth without intentional delay, typically within seconds following delivery, before significant placental transfusion occurs. Neonatal care is initiated immediately after clamping according to standard practice.",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Mohammed Amine MA Hannachi, Assistant professor","CONTACT","+21699696332","mohammedamine.hannachi@fmt.utm.tn",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Khaled Neji, Professor","+21651352742","DRKHALEDNEJI21@GMAIL.COM",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Maternity and neonatology center of Tunis","RECRUITING","Tunis","Tunis Governorate","1007","Tunisia","TN",{"type":48,"coordinates":49},"Point",[50,51],10.16579,36.81897,{"lat":51,"lon":50},[54,58,59],{"name":55,"role":31,"phone":56,"phoneExt":24,"email":57},"Mohammed Amine Hannachi","99696332","medaminehannachi3@gmail.com",{"name":24,"role":31,"phone":24,"phoneExt":24,"email":57},{"name":60,"role":61,"phone":24,"phoneExt":24,"email":24},"Mohammed Amine MA Hannachi, Assistant Professor","PRINCIPAL_INVESTIGATOR",{"type":61,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Mohammed Amine HANNACHI","Assistant Professor in Gynecology and Obstetrics","100053679","delayed-versus-immediate-cord-clamping-in-preterm-birth-100053679",false,"NCT07699666","Delayed Versus Immediate Cord Clamping in Preterm Birth","Early Neonatal Outcomes After Delayed Versus Immediate Cord Clamping in Preterm Birth: A Comparative Study From A Tunisian Tertiary Maternity Center","PREM-CORD","Inclusion Criteria:\n\n* Preterm neonates born at gestational age between 32 and 37 weeks\n* Live-born infants delivered in the study center\n* Singleton pregnancies\n* Parental consent obtained when applicable according to institutional ethical requirements\n\nExclusion Criteria:\n\n* Major congenital malformations or chromosomal abnormalities\n* Need for immediate advanced resuscitation at birth\n* Severe fetal distress requiring emergency obstetric intervention incompatible with protocol allocation\n* Placental conditions contraindicating delayed cord clamping (e.g., placental abruption with maternal instability, placenta previa bleeding, Placenta accreta spectrum)\n* Intra Uterin Growth Restriction with abnormal umbilical artery Doppler velocimetry","ALL","0 Days",{"count":76,"type":77},200,"ESTIMATED","INTERVENTIONAL",[80],"NA","The goal of this study is to evaluate whether delayed cord clamping improves early neonatal outcomes compared with immediate clamping in preterm birth.\n\nPreterm infants are at higher risk of neonatal complications, and the timing of cord clamping may influence placental transfusion and neonatal adaptation after birth. Delayed cord clamping may increase blood volume, improve iron stores, and reduce some neonatal morbidities, while immediate cord clamping is still commonly practiced in many settings.\n\nIn this study, preterm newborns are assigned to either delayed or immediate cord clamping according to a predefined protocol. Early neonatal outcomes, including respiratory status, need for resuscitation, hemoglobin levels, and early morbidity and mortality, will be assessed.\n\nThe study is conducted in a tertiary maternity center in Tunisia.",[83,84,85,86,87,88,89,90],"Preterm Birth Complication","Neonatal Morbidity and Mortality","Cord Clamping","Delayed Cord Clamping","Anemia","NEC - Necrotizing Enterocolitis","Intraventricular Hemorrhage Neonatal","Respiratory Distress Neonatal",[92,93,94,95,96,97,98,99,100,45],"Delayed cord clamping","Immediate cord clamping","Preterm infants","Preterm birth","Umbilical cord clamping","Neonatal outcomes","Placental transfusion","Neonatal morbidity","Neonatal mortality","2026-07-08",{"date":103,"type":104},"2026-07-13","ACTUAL",{"date":106,"type":104},"2025-10-02",{"date":108,"type":77},"2026-12-31",{"name":5,"class":6},1]