[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611331":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":25,"locations":40,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":89,"whyStopped":25,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Demineralized Dentin Matrix (DDM) + Platelet-Rich Fibrin (PRF)","EXPERIMENTAL","Participants in this group will receive socket grafting using Demineralized Dentin Matrix (DDM) prepared from their own extracted tooth. The dentin is cleaned, ground into particles, demineralized using 0.6 N hydrochloric acid, rinsed with saline, and mixed with autologous Platelet-Rich Fibrin (PRF) before being placed into the extraction socket. The socket is then closed with resorbable sutures for healing.",[13],"Biological: Demineralized Dentin Matrix (DDM) + Platelet-Rich Fibrin (PRF)",{"label":15,"type":16,"description":17,"interventionNames":18},"Mineralized Plasmatic Matrix (MPM)","ACTIVE_COMPARATOR","Participants in this group will receive socket grafting using a Mineralized Plasmatic Matrix (MPM) composed of a commercially available xenograft mixed with Platelet-Rich Plasma (PRP). The mixture forms a cohesive mineralized matrix that is placed into the extraction socket and stabilized with sutures.",[19],"Biological: Mineralized Plasmatic Matrix (MPM)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BIOLOGICAL","Autogenous dentin-derived grafting material is used as a bone substitute for alveolar ridge preservation following molar extraction. PRF, obtained from the patient's centrifuged blood, is mixed with DDM to enhance graft stability and promote healing.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"A xenogenic bone substitute is mixed with autologous platelet-rich plasma to form a mineralized plasmatic matrix, which serves as a control graft for ridge preservation after molar extraction.",[15],[30,34,37],{"name":31,"affiliation":32,"role":33},"Tarek Ibrahim ElGhareeb, Phd","Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University","STUDY_CHAIR",{"name":35,"affiliation":32,"role":36},"Salah Eldin ElAbbasy, Phd","STUDY_DIRECTOR",{"name":38,"affiliation":32,"role":39},"Ahmed Suliman Ahmed, Bds","PRINCIPAL_INVESTIGATOR",[41],{"facility":42,"status":25,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Faculty of Dentistry, Cairo University - Department of Oral and Maxillofacial Surgery","Cairo","12613","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.24967,30.06263,{"lat":51,"lon":50},[54],{"name":55,"role":56,"phone":57,"phoneExt":25,"email":58},"Faculty of Dentistry, Cairo University.","CONTACT","23634965","dentmail@dentistry.cu.edu.eg",{"type":39,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ahmed Suliman Ahmed Badr","Dr","100611331","demineralized-dentin-matrix-versus-mineralized-plasmatic-matrix-on-alveolar-ridge-preservation-in-molar-extraction-sites-100611331",false,"NCT07239193","Demineralized Dentin Matrix Versus Mineralized Plasmatic Matrix on Alveolar Ridge Preservation in Molar Extraction Sites","Effect of Demineralized Dentin Matrix Versus Mineralized Plasmatic Matrix on Alveolar Ridge Preservation in Molar Extraction Sites; A Randomized Clinical Trial.","Inclusion Criteria:\n\n\\- Non-restorable tooth indicated for extraction Multi-rooted teeth Age group of 18 to 55 years Patients free from any systemic disease that may affect bone healing.\n\nExclusion Criteria:\n\n\\- Pregnant females Active infection at extraction site Smokers Systemic conditions affecting healing (e.g. diabetes, medications as bisphosphonates...) Poor oral hygiene. Patient with systemic disease that may affect bone healing. o Uncooperative patient.","ALL","18 Years","55 Years",{"count":73,"type":74},24,"ESTIMATED","INTERVENTIONAL",[77],"NA","When a tooth is removed, the bone around it (called the alveolar ridge) naturally shrinks. This study compares two bone grafting materials to find out which one better preserves bone after molar extraction:\n\nDemineralized Dentin Matrix (DDM): A material made from the patient's own extracted tooth, treated to remove minerals while keeping bone-forming proteins.\n\nMineralized Plasmatic Matrix (MPM): A mixture of a standard bone substitute and platelet-rich plasma from the patient's blood.",[80,81],"Socket Preservation","Alveolar Ridge Preservation",[83,84,85,86,87,88],"socket preservation","alveolar ridge preservation","DDM","demineralized dentin matrix","MPM","mineralized plasmatic matrix","NOT_YET_RECRUITING","2025-11-16",{"date":92,"type":93},"2025-11-20","ACTUAL",{"date":95,"type":74},"2025-12-01",{"date":97,"type":74},"2026-11-01",{"name":5,"class":6},1]