[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637757":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":25,"responsibleParty":40,"collaborators":44,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":25,"enrollmentInfo":58,"targetDuration":25,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":25,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":25},{"fullName":5,"class":6},"UConn Health","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active filtration","EXPERIMENTAL","Air purifiers with HEPA filters",[13],"Other: Portable air purifiers with HEPA filtration",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham filtration","SHAM_COMPARATOR","Air purifiers lacking HEPA filters",[19],"Other: Portable air purifiers without filtration (sham)",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Portable air purifiers with HEPA filtration","Portable air purifiers filter air and reduce exposure to air pollutants, in this case, airborne particulate matter",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Portable air purifiers without filtration (sham)","Air purifiers with filters removed (sham)",[15],[31],{"name":32,"affiliation":5,"role":33},"Doug M Brugge","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Doug Brugge, PhD","CONTACT","18606748814","brugge@uchc.edu",{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Douglas Brugge","Professor and Chair",[45],{"name":46,"class":47},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100637757","democratizing-access-to-cleaner-residential-air-100637757",false,"NCT07629518","Democratizing Access to Cleaner Residential Air","DACRA","Inclusion Criteria:\n\nAge 40 years or older Speaks English, Vietnamese, and\u002For Chinese Cognitive capacity to respond to questionnaires Lives fulltime at the current address, adjacent (\\\u003C 200 meters) to roadways with large traffic volumes Must have one or more risk factors (hypertension or elevated blood pressure, pre-diabetes or diabetes or elevated blood sugar levels, elevated cholesterol levels, body mass index 25 or greater)\n\nExclusion Criteria:\n\nPregnant Works between the hours of 10 PM and 6 AM Sources of smoke in the living space (such as candles, incense, marijuana, wood stove, fireplace) almost every day\u002Fevery day.\n\nEvery day exposure to motor vehicle exhaust (from cars, trucks, buses, trains), including heavy street or highway traffic.\n\nCurrently smoking or vaping Others smoking or vaping indoors, in the living space. Within the past 5 years, a diagnosis of heart attack, heart disease, stroke, blood clots or pulmonary embolism, cancer requiring surgery and\u002For chemo\u002Fradiation therapy",true,"ALL","40 Years",{"count":59,"type":60},66,"ESTIMATED","INTERVENTIONAL",[63],"NA","The purpose of this research study is to determine whether the use of in-home air filtration to reduce exposure to air pollution benefits health.",[66],"Cardiovascular (CV) Risk",[68,69,70,71,72],"air pollution","air purifiers","HEPA filtration","cardiovascular risk","biomarkers","NOT_YET_RECRUITING","2026-06-01",{"date":76,"type":77},"2026-06-05","ACTUAL",{"date":79,"type":60},"2026-09",{"date":81,"type":60},"2029-05",{"name":42,"class":6}]