[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504386":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":47,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":52,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute Respiratory Distress Syndrome",null,"Adults admitted to ICU with ARDS confirmed according to Berlin Definition",[13],"Device: Masimo O3 NIRS cerebral oximetry and SedLine processed EEG",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Masimo O3 NIRS cerebral oximetry and SedLine processed EEG","Non-invasive neuromonitoring device for observational study",[9],[21],{"name":22,"affiliation":5,"role":23},"Asher Mendelson, MD PhD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","204-787-8059","asher.mendelson@umanitoba.ca",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Health Sciences Centre Winnipeg","RECRUITING","Winnipeg","Manitoba","R3T2N2","Canada","CA",{"type":39,"coordinates":40},"Point",[41,42],-97.14704,49.8844,{"lat":42,"lon":41},[45],{"name":22,"role":26,"phone":46,"phoneExt":10,"email":28},"2047878059",{"type":23,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Asher Mendelson","Assistant Professor","100504386","depth-of-sedation-and-its-impact-on-cerebrovascular-reactivity-in-acute-respiratory-distress-syndrome-a-pilot-analysis-100504386",false,"NCT05847634","Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis","Inclusion Criteria:\n\n* Adult patient admitted to the ICU\n* ARDS confirmed according to the Berlin Definition\n* Invasive mechanical ventilation\n* Deep sedation and\u002For neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team\n* Application of monitoring devices feasible\n\nExclusion Criteria:\n\n* More than 24 hours elapsed since ICU admission\n* Death is deemed imminent and inevitable during the next 24 hours\n* Known allergy to a textile component of the device\n* Consent declined from patient or authorized third party\n* The treating clinician believes that participation in the study would not be in the best interest of the patient","ALL","18 Years",{"count":59,"type":60},40,"ESTIMATED","OBSERVATIONAL","Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue oxygenation (StO2) in the brain, for patients with acute respiratory distress syndrome (ARDS) in the ICU.",[64],"ARDS, Human",[66,67,68,69,9],"Near-Infrared Spectroscopy","Depth of Sedation","Intensive Care Unit","Electroencephalography","2024-12-03",{"date":72,"type":73},"2024-12-06","ACTUAL",{"date":75,"type":73},"2024-11-25",{"date":77,"type":60},"2026-01",{"name":5,"class":6},1]