[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559364":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":32,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CXR receipients",null,"Patients who will receive CXR after lung biopsy",[13],"Diagnostic Test: CXR",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","CXR","CXRs will be performed at 3 different time points - (i) within 1 hour after TTLB, (ii) at 4 hours (± 1 hour) after TTLB and (iii) at 18 hours (± 2 hours) after TTLB.",[9],[21],{"name":22,"affiliation":5,"role":23},"David SC Hui, MD","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Ka Pang Chan, MBChB","CONTACT","+852 3505 2211","chankapang@cuhk.edu.hk",{"name":26,"role":27,"phone":31,"phoneExt":10,"email":29},"+852 3505 3396",[33],{"facility":5,"status":34,"city":35,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Hong Kong","HK",{"type":38,"coordinates":39},"Point",[40,41],114.17469,22.27832,{"lat":41,"lon":40},[44,45],{"name":26,"role":27,"phone":31,"phoneExt":10,"email":29},{"name":22,"role":27,"phone":46,"phoneExt":10,"email":47},"+852 2632 3128","dschui@cuhk.edu.hk",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ka Pang Chan","Assistant Professor","100559364","detection-and-prediction-of-clinically-significant-pneumothorax-after-image-guided-transthoracic-lung-biopsy-100559364",false,"NCT06563167","Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy","Prospective Study on Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy","Inclusion Criteria:\n\n* Patients whose image-guided TTLB, including ultrasound or CT-guided, is arranged for diagnostic purposes\n* Patients who are able to sign written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients with resolution of lung lesion prior to the scheduled image-guided TTLB\n* Patients have active exacerbation of underlying diseases causing unstable respiratory conditions (e.g. exacerbation of COPD, pneumonia) which would lower the threshold for invasive interventions for iatrogenic pneumothorax\n* Patients with psychiatric disease or cognitive impairment that may limit their ability to understand or give consent to the study\n* Patients who decline to join the study","ALL","18 Years",{"count":62,"type":63},330,"ESTIMATED","1 Month","OBSERVATIONAL","Objective: The goal of this study is to evaluate the sensitivity and specificity of the presence of pneumothorax on a 4-hour CXR after image-guided transthoracic lung biopsy (TTLB) for diagnosing subsequent clinically significant pneumothorax.\n\nHypothesis to be tested: The investigators hypothesize that an absence of pneumothorax on CXR at 4 hours can accurately predict an absence of clinically significant pneumothorax at 16 to 20 hours.\n\nDesign and subjects: This is a prospective, single-centre, diagnostic accuracy study conducted at a tertiary referral centre in Hong Kong. Patients will be recruited if an image-guided TTLB is arranged.\n\nStudy instruments: CXRs will be performed for patients at different time points. The presence and size of pneumothorax (if any) will be recorded.\n\nOutcome: The diagnostic capacity of a 4-hour CXR after image-guided TTLB will be provide evidence regarding the safety and patient selection for same-day discharge.",[68],"Lung Biopsy","2025-03-08",{"date":71,"type":72},"2025-03-11","ACTUAL",{"date":74,"type":72},"2024-09-01",{"date":76,"type":63},"2026-12-31",{"name":5,"class":6},1]