[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606100":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":47,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Harran University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"individuals with odontogenic cysts",null,"The cyst fluid obtained during the puncture will be collected in a tube and centrifuged. The clear liquid remaining on top will be transferred to an Eppendorf tube and stored at -80 degrees. After all samples are collected, they will be analyzed using the ELISA method.",[13],"Other: cyst fluid examination",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"cyst fluid examination","Participants will not undergo any procedures outside of the routine for the study. The cyst fluid obtained during the puncture will be collected in a tube and centrifuged at 3000 rpm for 20 minutes at 4 degrees Celsius. The Eppendorf tubes will be stored at -80 °C until the clear liquid remaining above is taken and examined, without removing the particles that have settled at the bottom of the tube. The biochemical parameters of the cyst fluid obtained from the study participants will be analyzed using the ELISA method. MMP-8, MMP-9, RANKL, and MIP1alpha will be analyzed using commercially available ELISA kits, following the manufacturer's instructions.",[9],[20],{"name":21,"affiliation":5,"role":22},"hande has elci","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"mine alkaya karagoz","CONTACT","905365417606","minekaragoz@harran.edu.tr",{"name":21,"role":26,"phone":30,"phoneExt":10,"email":31},"905076577647","handehaselci@harran.edu.tr",[33],{"facility":34,"status":35,"city":36,"state":10,"zip":10,"country":37,"countryCode":10,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Harran University, Faculty of Dentistry","RECRUITING","Sanliurfa","Turkey (Türkiye)",{"type":39,"coordinates":40},"Point",[41,42],38.79392,37.16708,{"lat":42,"lon":41},[45,46],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":21,"role":26,"phone":30,"phoneExt":10,"email":31},{"type":22,"investigatorFullName":25,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Assistant Professor","100606100","detection-of-disease-marker-factors-in-cyst-fluid-100606100",false,"NCT07171151","Detection of Disease Marker Factors in Cyst Fluid","Measurement of MMP-8, MMP-9, RANKL, MIP-1alpha in Biopsy Samples From Odontogenic Cyst Patients","Inclusion Criteria:\n\n1. Individuals diagnosed with cysts\n2. Individuals who are not pregnant or breastfeeding\n3. Individuals who agree to sign the informed consent form\n\nExclusion Criteria:\n\n1. Systemically ill individuals who are contraindicated for surgery.\n2. Individuals who do not wish to sign the informed consent form.\n3. Individuals who are pregnant, breastfeeding, or using oral contraceptives will be excluded.","ALL","12 Years","80 Years",{"count":60,"type":61},25,"ESTIMATED","2 Weeks","OBSERVATIONAL","The purpose of this observational study is to examine the cyst fluid obtained after a puncture procedure performed for cyst diagnosis in participants with cystic lesions on clinical and radiological examination.The main question it aims to answer is:\n\n\\- What is the exact mechanism of formation of odontogenic cysts?\n\nBiomarkers in the cyst fluid obtained after a puncture procedure performed as part of the diagnosis and treatment process of odontogenic cysts will be examined. The aim of this study is to gain insight into cyst pathology by examining the levels of biomarkers in odontogenic cyst fluid.",[66],"Biomarkers",[68,69,70,71],"odontogenic cysts","biomarkers","MMP-8","MIP-1alfa","2025-09-09",{"date":74,"type":75},"2025-09-12","ACTUAL",{"date":77,"type":75},"2025-08-25",{"date":79,"type":61},"2026-05",{"name":5,"class":6},1]