[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100443065":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":42,"centralContacts":46,"locations":52,"responsibleParty":71,"collaborators":10,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":10,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":10,"enrollmentInfo":82,"targetDuration":10,"studyType":85,"phases":10,"briefSummary":86,"conditions":87,"keywords":10,"overallStatus":55,"whyStopped":10,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Observational (biospecimen collection, Pap smear)",null,"Patients undergo collection of blood samples for liquid biopsy during pre-treatment consultation before hysterectomy, after hysterectomy but before starting any chemotherapy, and at the end of last chemotherapy cycle. Patients also undergo collection of tissue samples during hysterectomy. Patients may also undergo Pap smears before and after hysterectomy.",[13,14,15],"Procedure: Biospecimen Collection","Procedure: Liquid Biopsy","Other: Pap Smear",[17,24,30],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"PROCEDURE","Biospecimen Collection","Undergo collection of blood and tissue samples",[9],[23],"Biological Sample Collection",{"type":18,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"Liquid Biopsy","Undergo liquid biopsy",[9],[29],"Plasma Biopsy",{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Pap Smear","Undergo Pap smear",[9],[35,36,37,38,39,40,41],"Cervical Smear Preparation","Cervical Smear Procedure","Pap Smear Procedure","Pap Test","Papanicolaou Smear Procedure","Papanicolaou Test","Vaginal Smears",[43],{"name":44,"affiliation":5,"role":45},"Pamela T Soliman","PRINCIPAL_INVESTIGATOR",[47],{"name":48,"role":49,"phone":50,"phoneExt":10,"email":51},"Pamela T Soliman, MD","CONTACT","713-745-2352","psoliman@mdanderson.org",[53],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"M D Anderson Cancer Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-95.36327,29.76328,{"lat":65,"lon":64},[68,70],{"name":69,"role":49,"phone":50,"phoneExt":10,"email":51},"Pamela T. Soliman",{"name":69,"role":45,"phone":10,"phoneExt":10,"email":10},{"type":72,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100443065","determine-the-utility-of-liquid-biopsies-and-tumor-molecular-profiling-in-predicting-recurrence-in-endometrial-cancers-100443065",false,"NCT05049538","Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers","A Pilot Investigation to Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancer","Inclusion Criteria:\n\n* Women age 18 years and older\n* Histologic diagnosis of endometrial cancer\n* Candidate for primary surgical treatment or has recently had prior primary surgery\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\nPatients who have received prior treatment including chemotherapy or radiation therapy for endometrial cancer. Prior hormonal therapy for the treatment of endometrial cancer is allowed. Patients with prior primary surgery will be allowed to enroll in this trial if the patient has not received any chemotherapy or radiation at the time of enrollment. Note: patients with a history of other cancers may be enrolled after discussion with the PI if it is determined that they are at low risk for recurrence or metastasis.","FEMALE","18 Years",{"count":83,"type":84},1000,"ESTIMATED","OBSERVATIONAL","This study is to find out how well liquid biopsies work as a non-invasive alternative to other methods of finding cancer cells (such as a tissue biopsy) in patients with endometrial cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help doctors learn how the cells in the blood may change during treatment for uterine cancer.",[88,89,90,91,92,93],"Endometrial Clear Cell Adenocarcinoma","Endometrial Dedifferentiated Carcinoma","Endometrial Mucinous Adenocarcinoma","Endometrial Serous Adenocarcinoma","Malignant Uterine Neoplasm","Uterine Corpus Carcinosarcoma","2026-04-30",{"date":96,"type":97},"2026-05-06","ACTUAL",{"date":99,"type":97},"2019-06-18",{"date":101,"type":84},"2028-06-30",{"name":5,"class":6},1]