[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585010":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":40,"responsibleParty":61,"collaborators":64,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":23,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":43,"whyStopped":23,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Queen's University, Belfast","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Visit 1: Protein\u002Ffat then carbohydrate. Visit 2: Carbohydrate then protein\u002Ffat.","EXPERIMENTAL","Participants who are randomised to eat the protein\u002Ffat-based component (scrambled egg) of the meal before the carbohydrate-based component (wholemeal toast) on their first study visit and on their second study visit they will be asked to eat the meal in the reverse order. The order in which this occurs will be randomised and each participant will act as their own control.",[13],"Other: Visit 1: Protein\u002Ffat then carbohydrate. Visit 2: Carbohydrate then protein\u002Ffat.",{"label":15,"type":10,"description":16,"interventionNames":17},"Visit 1: Carbohydrate then protein\u002Ffat. Visit 2: Protein\u002Ffat then carbohydrate.\"","Participants who are randomised to eat the carbohydrate-based component (wholemeal toast) of the meal before the protein\u002Ffat-based component (scrambled egg) on their first study visit and on their second study visit they will be asked to eat the meal in the reverse order. The order in which this occurs will be randomised and each participant will act as their own control.",[18],"Other: Visit 1: Carbohydrate then protein\u002Ffat. Visit 2: Protein\u002Ffat then carbohydrate.",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"Participants who are randomised to eat the protein\u002Ffat-based component (scrambled egg) of the meal before the carbohydrate-based component (wholemeal toast) on their first study visit, will be asked to eat the meal in the reverse order at their second study visit. Meals will be prepared by members of the research team who have completed Food Safety training. Participants will be asked to consume a 440kcal breakfast meal within 10 minutes, approximately 1.5 hours after arrival at their first study visit and approximately 30 minutes after arrival at their second study visit.",[9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Visit 1: Carbohydrate then protein\u002Ffat. Visit 2: Protein\u002Ffat then carbohydrate.","Participants who are randomised to eat the carbohydrate-based component (wholemeal toast) of the meal before the protein\u002Ffat-based component (scrambled egg) on their first study visit, will be asked to eat the meal in the reverse order at their second study visit. Meals will be prepared by members of the research team who have completed Food Safety training. Participants will be asked to consume a 440kcal breakfast meal within 10 minutes, approximately 1.5 hours after arrival at their first study visit and approximately 30 minutes after arrival at their second study visit.",[15],[29],{"name":30,"affiliation":5,"role":31},"Hannah O'Hara, MBBS BSc PhD DFSRH MRCGP","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":23,"email":36},"CONTACT","+44 (0) 28 9097 6350","h.ohara@qub.ac.uk",{"name":38,"role":34,"phone":35,"phoneExt":23,"email":39},"Danielle Logan, PhD","d.logan@qub.ac.uk",[41],{"facility":42,"status":43,"city":44,"state":23,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Centre for Public Health, Institute of Clinical Sciences A","RECRUITING","Belfast","BT12 6BA","United Kingdom","UK",{"type":49,"coordinates":50},"Point",[51,52],-5.92541,54.59682,{"lat":52,"lon":51},[55,56,57,58],{"name":30,"role":34,"phone":35,"phoneExt":23,"email":36},{"name":38,"role":34,"phone":35,"phoneExt":23,"email":39},{"name":30,"role":31,"phone":23,"phoneExt":23,"email":23},{"name":59,"role":60,"phone":23,"phoneExt":23,"email":23},"Jayne Woodside, PhD","SUB_INVESTIGATOR",{"type":31,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Hannah O'Hara","Dr",[65],{"name":66,"class":6},"Imperial College London","100585010","determining-the-effect-of-food-ordering-on-blood-glucose-in-gestational-diabetes-mellitus-defi-gdm-100585010",false,"NCT06896799","Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM)","Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM) - a Randomised Crossover Study","DEFI-GDM","Inclusion Criteria:\n\n* Pregnant women with gestational diabetes mellitus\n* Aged 18-50 years old\n\nExclusion Criteria:\n\n* History of type 1 or type 2 diabetes mellitus\n* Dietary restrictions or clinically confirmed food allergies that may affect study requirements\n* Pharmacologically managed GDM at the point of study entry\n* Hyperemesis gravidarum at the point of study entry (i.e. prolonged\u002Fsevere nausea and vomiting)\n* Using antiemetic medication (e.g. dimenhydrinate, prochlorperazine, promethazine)\n* Any other problems or medical conditions that would substantially limit their ability to complete the study requirements\n\nParticipants can be recruited onto the study if they have previously had GDM in another pregnancy. Participants can also be recruited if they are involved in other research studies, but this will depend on the study type and the decision will be made by the Chief\u002FPrincipal Investigator.","FEMALE","18 Years","50 Years",{"count":79,"type":80},35,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this clinical trial is to determine whether the sequence of macronutrient consumption affects post-prandial glycaemia in women with gestational diabetes mellitus.\n\nThe main questions it aims to answer are:\n\n* The difference in the magnitude of postprandial rise in blood glucose between the two test meals.\n* The difference in the magnitude of postprandial change in serum levels of gut hormones between the two test meals.\n* The difference in mean change in pre-post ingestion satiety scores between the two test meals.\n* The difference in 24 hour energy and macronutrient intake following the two test meals.\n\nParticipants will attend two study visits at the Centre for Public Health, with an interval of at least two days between the visits and complete the following, anthropometric measurements, demographic and appetite questionnaires, glucose measurements, two food diaries and fasting blood samples and the consumption of the study breakfast. Participants will be asked to eat either the protein\u002Ffat-based component of the meal (scrambled egg) before or after the carbohydrate-based component (wholemeal toast) on their first visit and on the other visit they will be asked to eat the meal in the reverse order. The order in which this occurs will be randomised and each participant will act as their own control. Researchers will compare the results from participants between the two test meals to see if the order of macronutrient consumption has any effect on post-prandial glycaemia, gut hormones, satiety scores and energy and macronutrient intake.",[86],"Gestational Diabetes Mellitus (GDM)",[88,89,90],"Gestational Diabetes Mellitus","Post-prandial glycaemia","Food Ordering","2026-04-14",{"date":93,"type":94},"2026-04-17","ACTUAL",{"date":96,"type":94},"2025-12-11",{"date":98,"type":80},"2027-02-01",{"name":5,"class":6},1]