[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602829":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":56,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Arcadia University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active tDCS","ACTIVE_COMPARATOR","This group will receive 20 minutes of active anodal tDCS",[13],"Device: active transcranial direct current stimulation (tDCS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham tDCS","SHAM_COMPARATOR","This group will receive sham anodal tDCS. The tDCS unit will be active for the first 30 seconds and the last 30 seconds only.",[19],"Device: sham transcranial direct current stimulation (tDCS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","active transcranial direct current stimulation (tDCS)","20 minutes of anodal tDCS over the primary motor cortex contralateral to the participants surgical limb during a quadriceps torque matching task",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"sham transcranial direct current stimulation (tDCS)","Participants receive sham tDCS in which the device only delivers current during the first and last 30 seconds while participants perform a quadriceps torque matching task",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Ryan Zarzycki, PhD","CONTACT","215-572-2852","zarzyckir@arcadia.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Ryan Zarzycki","RECRUITING","Glenside","Pennsylvania","19038","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-75.15212,40.10233,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":55,"phoneExt":26,"email":36},"Ryan Zarzycki, PT, PhD","215-572-8527",{"type":57,"investigatorFullName":39,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Associate Professor",[60],{"name":61,"class":62},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100602829","determining-the-effects-of-non-invasive-brain-stimulation-to-improve-quadriceps-muscle-function-after-acl-reconstruction-100602829",false,"NCT07128602","Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction","Determining the Effects of Non-invasive Brain Stimulation to Improve Quadriceps Muscle Function After ACL Reconstruction.","Inclusion Criteria:\n\n\\- females 2-6 months after ACL reconstruction\n\nExclusion Criteria:\n\n* multiple ligament reconstruction\n* osteochondral procedures\n* any previous lower extremity surgery\n* previous ACL injury\n* Metal or implants in the head or neck\n* history of neurological disease\n* seizures\n* severe migraines\n* concussion within the last 6 months","FEMALE","18 Years","35 Years",{"count":74,"type":75},42,"ESTIMATED","INTERVENTIONAL",[78],"NA","After knee surgery for a torn ACL, many women struggle with weak thigh muscles for years, partly due to reduced brain signals to these muscles. Our research tests a new approach to improve recovery by using low-level brain stimulation to boost these signals. The investigators will study 42 women, aged 18-35, who had ACL surgery. They'll be split into two groups: one receiving real brain stimulation and another getting a placebo, both during thigh-strengthening exercises. Over six sessions, the investigators measure thigh muscle strength, speed, and steadiness, plus two brain signal measures, using special equipment. The investigators will also check if stronger brain signals lead to better muscle performance, especially in women. Our goal is to show that this new method strengthens thigh muscles better than standard rehab, helping women recover better after surgery. If successful, this could improve physical therapy for women recovering from ACL surgery, making daily activities and return to sport easier.",[81,82],"Anterior Cruciate Ligament Reconstruction Rehabilitation","Quadriceps Muscle Function",[84,85,86,87],"acl","acl reconstruction","corticospinal excitability","non-invasive brain stimulation","2026-05-05",{"date":90,"type":91},"2026-05-07","ACTUAL",{"date":93,"type":91},"2025-06-06",{"date":95,"type":75},"2028-03-01",{"name":5,"class":6},1]