[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100327688":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":52,"collaborators":7,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":7,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":7,"studyType":67,"phases":7,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":39,"whyStopped":7,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Memorial Sloan Kettering Cancer Center","OTHER",null,[9,12,15,18,21],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V)","the WISC-V assessment produces a Full Scale IQ (FSIQ) used for primary power consideration in this study. The FSIQ is the most comprehensive global ability score on the WISC-V, and it has been conventionally reported and interpreted as an estimation of overall intellectual ability",{"type":6,"name":13,"description":14,"armGroupLabels":7,"otherNames":7},"California Verbal Learning Test, Children's Version","Used to assess verbal learning and memory in children and adolescents",{"type":6,"name":16,"description":17,"armGroupLabels":7,"otherNames":7},"Beery Developmental Test of Visual Motor Integration, 6th edition","Helps assess visual-motor skills in children and adults.",{"type":6,"name":19,"description":20,"armGroupLabels":7,"otherNames":7},"Grooved Pegboard Test","Measures dexterity",{"type":6,"name":22,"description":23,"armGroupLabels":7,"otherNames":7},"Behavior Assessment System for Children\u002FParent Report","The Behavior Assessment System for Children\u002FParent Report is a questionnaire that assesses the social-emotional and behavioral functioning (e.g., anxiety, depression, attention, hyperactivity, adaptability, leadership, social skills, etc.) in children between the ages of 2 and 22 years, and is available in English and Spanish.",[25],{"name":26,"affiliation":5,"role":27},"Vittoria Arslan Carlon, MD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":7,"email":32},"CONTACT","212-639-2680","arslancv@mskcc.org",{"name":34,"role":30,"phone":35,"phoneExt":7,"email":36},"David Abramson, MD","212-639-7232","abramsod@mskcc.org",[38],{"facility":5,"status":39,"city":40,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","New York","10065","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-74.00597,40.71427,{"lat":48,"lon":47},[51],{"name":26,"role":30,"phone":31,"phoneExt":7,"email":7},{"type":53,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100327688","determining-whether-multiple-anesthesia-exposures-affect-cognitive-function-for-retinoblastoma-patients-100327688",false,"NCT03546387","Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients","Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures","Inclusion Criteria:\n\n* Age ≥ 6 and \\\u003C 17 years old\n\nExclusion Criteria:\n\n* Diagnosis of any secondary disease associated with developmental delay\n* History of second cancer diagnosis\n* Legal Blindness\n* Past surgery of any type, with the exception of enucleation for retinoblastoma\n* Past exposure to anesthesia for surgical intervention\n* More than one anesthesia encounter for surgical intervention before diagnosis at MSK\n* Past External Beam Radiation for treatment of retinoblastoma\n* Past systemic chemotherapy\n* Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish","ALL","6 Years","17 Years",{"count":65,"type":66},75,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.",[70,71],"Pediatric Retinoblastoma","Retinoblastoma",[73,5],"18-126","2026-06-01",{"date":76,"type":77},"2026-06-03","ACTUAL",{"date":79,"type":77},"2018-05-07",{"date":81,"type":66},"2027-05-07",{"name":5,"class":6},1]