[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100434493":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":28,"responsibleParty":52,"collaborators":55,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":10,"maxAge":10,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":97,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Blunt trauma patients undergoing abdominopelvic computed tomographic imaging",null,"The study will be observational and not alter the care or management of blunt injury victims. Medical decisions will be made by treating physicians using current standards of care. Thus, to reduce the potential for bias, the study will seek to enroll all blunt injury victims who undergo A\u002FP imaging as part of their ED trauma evaluation. This may include children, the elderly, all races, both sexes, and any other demographic or social groups that may present among blunt injury patients. An individual will become eligible for the study when the treating physician determines that A\u002FP CT imaging is needed for their trauma evaluation. Inclusion or exclusion will not be based on age, gender, pregnancy or child-bearing potential, or racial\u002Fethnic origin.\n\nThere will be no exclusion criteria.",[13],"Other: There are no interventions associated with this study",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"There are no interventions associated with this study","This study is purely observational, there will be no interventions or changes in care related to patient inclusion in this study.",[9],[20],{"name":21,"affiliation":5,"role":22},"William R Mower, MD, PhD","STUDY_DIRECTOR",[24],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","(310) 794-0599","wmower@ucla.edu",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Ronald Reagan Hospital","RECRUITING","Los Angeles","California","90024","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-118.24368,34.05223,{"lat":41,"lon":40},[44,45,48,50],{"name":21,"role":25,"phone":10,"phoneExt":10,"email":27},{"name":46,"role":47,"phone":10,"phoneExt":10,"email":10},"Robert M Rodriguez, MD","PRINCIPAL_INVESTIGATOR",{"name":49,"role":47,"phone":10,"phoneExt":10,"email":10},"Ali S Raja, MD, MPH",{"name":51,"role":47,"phone":10,"phoneExt":10,"email":10},"Malkeet Gupta, MD",{"type":47,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"William Mower","Professor of Emergency Medicine, David Geffen School of Medicine at UCLA",[56,58,60,63,65,67],{"name":57,"class":6},"Brigham and Women's Hospital",{"name":59,"class":6},"University of California, San Francisco",{"name":61,"class":62},"Antelope Valley Hospital","UNKNOWN",{"name":64,"class":6},"Stanford University",{"name":66,"class":62},"UCSF - Fresno",{"name":68,"class":62},"UC Davis","100434493","developing-a-decision-instrument-to-guide-abdominal-pelvic-ct-imaging-of-blunt-trauma-patients-100434493",false,"NCT04937868","Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients","NEXUS AP CT","Inclusion Criteria:\n\nBlunt trauma patients who undergo abdominal-pelvic CT imaging during their initial trauma evaluation in the emergency department.\n\nExclusion Criteria:\n\nNone","ALL",{"count":78,"type":79},12000,"ESTIMATED","OBSERVATIONAL","Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of \"occult\" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the practice of obtaining computed tomography on virtually all patients with significant blunt trauma. This practice exposes large numbers patients to dangerous radiation at considerable expense, while detecting injuries in a small minority of cases.\n\nExisting data suggest that a limited number of criteria can reliably identify blunt injury victims who have \"no risk\" of abdominal or pelvic injuries, and hence no need for computed tomography (CT), without misidentifying any injured patient. It is estimated that nationwide implementation of such criteria could result in an annual reduction in radiographic charges of $75 million, and a significant decrease in radiation exposure and radiation induced malignancies.\n\nThis study seeks to determine whether \"low risk\" criteria can reliably identify patients who have sustained significant abdominal or pelvic injuries and safely decrease CT imaging of blunt trauma patients. This goal will be accomplished in the following manner:\n\nAll blunt trauma victims undergoing computed tomography of the abdomen\u002Fpelvis in the emergency department will undergo routine clinical evaluations prior to radiographic imaging. Based on these examinations, the presence or absence of specific clinical findings (i.e. abdominal\u002Fpelvic\u002Fflank pain, abdominal\u002Fpelvic\u002Fflank tenderness, bruising abrasions, distention, hip pain, hematuria, hypotension, tachycardia, low or falling hematocrit, intoxication, altered sensorium, distracting injury, positive FAST imaging, dangerous mechanism, abnormal x-ray imaging) will be recorded for each patient, as will the presence or absence of abdominal or pelvic injuries. The clinical findings will serve as potential imaging criteria. At the completion of the derivation portion of the study the criteria will be examined to find a subset that predicts injury with high sensitivity, while simultaneously excluding injury, and hence the need for imaging, in the remaining patients. These criteria will then be confirmed in a separate validation phase of the study.\n\nThe criteria will be considered to be reliable if the lower statistical confidence limit for the measured sensitivity exceeds 98.0%. Potential reductions in CT imaging will be estimated by determining the proportion of \"low-risk\" patients that do not have significant abdominal or pelvic injuries.",[83,84,85,86,87,88,89,90,91,92,93,94,95,96],"Abdominal Injury","Pelvic Fracture","Genital Hemorrhage","Lumbar Spine Injury","Hip Injuries","Liver Injury","Spleen Injury","Renal Injury","Diaphragm Injury","Aortic Rupture","Aortic Dissection","Bowel Disease","Vascular System Injuries","Sacral Fracture",[98,99,100,101,102,103,104,105,106],"Blunt trauma","Abdominal injury","Pelvic injury","Spine injury","Genital injury","Vascular injury","Hip injury","Computed tomography","Decision instrument","2026-01-09",{"date":109,"type":110},"2026-01-13","ACTUAL",{"date":112,"type":110},"2018-01-15",{"date":114,"type":79},"2027-06-15",{"name":5,"class":6},1]