[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555491":3},{"organization":4,"armGroups":7,"interventions":35,"overallOfficials":52,"centralContacts":57,"locations":67,"responsibleParty":85,"collaborators":39,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":39,"eligibilityCriteria":92,"healthyVolunteers":89,"sex":93,"minAge":94,"maxAge":39,"enrollmentInfo":95,"targetDuration":39,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":70,"whyStopped":39,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"National Cheng-Kung University Hospital","OTHER",[8,14,20,25,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","SHAM_COMPARATOR","Participants who are unwilling to undergo surgery, use a mandibular advancement device, utilize continuous positive airway pressure (CPAP) devices, or undergo oropharyngeal training. They will receive sleep hygiene education.",[13],"Other: Control Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Surgical Intervention","EXPERIMENTAL","Remove excessive soft tissue from the base of the tongue, soft palate, and\u002For tonsil.",[19],"Procedure: Surgical Intervention",{"label":21,"type":16,"description":22,"interventionNames":23},"Oropharyngeal Training (face-to-face)","Participants will attend face-to-face oropharyngeal training sessions with a therapist in the lab, each lasting 45-60 minutes, 1-2 times per week, over a 12-week intervention period.",[24],"Other: Oropharyngeal Training (face-to-face)",{"label":26,"type":16,"description":27,"interventionNames":28},"Oropharyngeal Training (telerehabilitation )","Participants will attend online oropharyngeal training (telerehabilitation) sessions with a therapist, each lasting 45-60 minutes, 1-2 times per week, over a 12-week intervention period.",[29],"Other: Oropharyngeal Training (telerehabilitation)",{"label":31,"type":16,"description":32,"interventionNames":33},"Continuous Positive Airway Pressure","Participants will use Continuous Positive Airway Pressure (CPAP) throughout the intervention period.",[34],"Device: Continuous Positive Airway Pressure",[36,40,44,46,49],{"type":6,"name":9,"description":37,"armGroupLabels":38,"otherNames":39},"sleep hygiene education",[9],null,{"type":41,"name":15,"description":42,"armGroupLabels":43,"otherNames":39},"PROCEDURE","Surgical Intervention includes uvulopalatopharyngoplasty (UPPP) and transoral robotic surgery (TORS). UPPP involves the removal of the uvula and tonsils, while TORS consists of the removal of the uvula, tonsils, and adipose tissue at the base of the tongue.",[15],{"type":6,"name":21,"description":22,"armGroupLabels":45,"otherNames":39},[21],{"type":6,"name":47,"description":27,"armGroupLabels":48,"otherNames":39},"Oropharyngeal Training (telerehabilitation)",[26],{"type":50,"name":31,"description":32,"armGroupLabels":51,"otherNames":39},"DEVICE",[31],[53],{"name":54,"affiliation":55,"role":56},"Ching-Hsia Hung, PhD","National Cheng Kung University","PRINCIPAL_INVESTIGATOR",[58,63],{"name":59,"role":60,"phone":61,"phoneExt":39,"email":62},"Jun-Hui Ong, MS","CONTACT","+886-9-37839992","junhui.ong611@gmail.com",{"name":54,"role":60,"phone":64,"phoneExt":65,"email":66},"+886-6-2353535","5939","chhung@mail.ncku.edu.tw",[68],{"facility":69,"status":70,"city":71,"state":39,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"National Cheng Kung University Hospital","RECRUITING","Tainan","701","Taiwan","TW",{"type":76,"coordinates":77},"Point",[78,79],120.21333,22.99083,{"lat":79,"lon":78},[82],{"name":83,"role":60,"phone":84,"phoneExt":65,"email":66},"Ching-Hsia Hung, Ph.D","06-2353535",{"type":86,"investigatorFullName":39,"investigatorTitle":39,"investigatorAffiliation":39,"oldNameTitle":39,"oldOrganization":39},"SPONSOR","100555491","developing-a-treatment-clustering-system-for-obstructive-sleep-apnea-using-polysomnographic-physiological-signals-100555491",false,"NCT06512779","Developing a Treatment Clustering System for Obstructive Sleep Apnea Using Polysomnographic Physiological Signals","Inclusion Criteria:\n\n* OSA patients\n* Aged over 20 years\n\nExclusion Criteria:\n\n* BMI≧ 32\n* Central or mixed types of sleep apnea\n* A history of malignancy or infection of the head and neck region and laryngeal trauma\n* Craniofacial malformation\n* Stroke\n* Neuromuscular disease\n* Severe cardiovascular disease\n* Active psychiatric disease\n* Structural abnormalities over the upper respiratory airway\n* Performed any operation or treatment over the neck before\n* Pregnancy","ALL","20 Years",{"count":96,"type":97},150,"ESTIMATED","INTERVENTIONAL",[100],"NA","Obstructive sleep apnea syndrome (OSA) is marked by repeated upper airway obstructions during sleep, affecting approximately 14% of men and 5% of women aged 30-70 years.\n\nHowever, precise clinical prediction tools for selecting optimal treatment strategies are lacking. This study aims to develop an automated treatment clustering system using artificial intelligence to classify patients based on etiology into (i) anatomical factors, (ii) reduced muscle responsiveness, and (iii) other non-anatomical factors. This system will analyze physiological sleep assessments, such as electromyography (EMG) and pneumotachographs, from a retrospective polysomnography (PSG) database. Cross-validation will be conducted on new OSA patients undergoing various management strategies, including surgical intervention, CPAP therapy, and oropharyngeal training (delivered face-to-face or via telerehabilitation). This system aims to enhance clinicians' ability to predict treatment success rates and improve patient outcomes.",[103],"Obstructive Sleep Apnea of Adult",[105,106],"Obstructive Sleep Apnea","Treatment Clustering System","2024-08-04",{"date":109,"type":110},"2024-08-06","ACTUAL",{"date":112,"type":110},"2024-07-30",{"date":114,"type":97},"2026-05-01",{"name":5,"class":6},1]