[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528988":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":22,"responsibleParty":41,"collaborators":43,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":7,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":7,"maxAge":7,"enrollmentInfo":72,"targetDuration":7,"studyType":75,"phases":7,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Keele University","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Karina T Wright, PhD","ISTM, Keele University","PRINCIPAL_INVESTIGATOR",[14,18],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","+441691404022","karina.wright1@nhs.net",{"name":19,"role":15,"phone":20,"phoneExt":7,"email":21},"Sharon J Owen, PhD","+441691404295","sharon.owen12@nhs.net",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust","RECRUITING","Oswestry","Shropshrie","SY10 7AG","United Kingdom","UK",{"type":32,"coordinates":33},"Point",[34,35],-3.05497,52.86195,{"lat":35,"lon":34},[38,39],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},{"name":40,"role":12,"phone":7,"phoneExt":7,"email":7},"Karina T Wright",{"type":42,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[44,46,48,50,52,55,58,60,61],{"name":45,"class":6},"Alder Hey Children's NHS Foundation Trust",{"name":47,"class":6},"Birmingham Women's and Children's NHS Foundation Trust",{"name":49,"class":6},"Norfolk and Norwich University Hospitals NHS Foundation Trust",{"name":51,"class":6},"Royal National Orthopaedic Hospital NHS Trust",{"name":53,"class":54},"Scottish National Blood Transfusion Service","UNKNOWN",{"name":56,"class":57},"NHS Blood and Transplant","OTHER_GOV",{"name":59,"class":6},"University of Birmingham",{"name":24,"class":57},{"name":62,"class":6},"The Royal Orthopaedic Hospital NHS Trust","100528988","developing-allogeneic-musculoskeletal-therapies-100528988",false,"NCT06167928","Developing Allogeneic Musculoskeletal Therapies","Investigating the Potential for Musculoskeletal Tissues and Cells Isolated From Juvenile Patients in the Development of Novel Therapies for Cartilage and Bone Injury and Osteoarthritis","Inclusion Criteria:\n\nFor juvenile\u002Finfant donors:\n\n* Parents\u002Fguardians being able to provide signed and dated informed consent form.\n* Scheduled for one of the following surgical treatments:\n\nDigit amputations due to polydactyly. Surgery to treat dislocated hips.\n\nFor biobank\u002FNHSBT donors\n\n* Informed consent via consenting institution.\n\nExclusion Criteria:\n\n* Parents\u002Fguardians not understanding the Patient Information Sheet",true,"ALL",{"count":73,"type":74},325,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other bio-banked cartilage tissues. The main question it aims to answer is:\n\nWhich of the following tissues from polydactyly digit, iliac apophysis or other bio-banked cartilage produce better cartilage in vitro and in vivo? Participants receiving digit amputation surgery for treatment of polydactyly will be asked to donate the associated waste tissue whilst participants receiving surgery to treat a dislocated hip will be asked to donate an extra small piece of cartilage tissue (approximately 1 gram) from the iliac apophysis. Other tissues for the study will be obtained from those donated to biobanks.",[78],"Osteoarthritis",[80,81,82],"Cell therapy","Musculoskeletal","Allogeneic","2026-06-09",{"date":85,"type":86},"2026-06-11","ACTUAL",{"date":88,"type":86},"2018-10-08",{"date":90,"type":74},"2037-09-01",{"name":5,"class":6},1]