[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589152":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":21,"locations":27,"responsibleParty":88,"collaborators":90,"id":98,"slug":99,"hasResults":100,"nctId":101,"briefTitle":102,"officialTitle":102,"acronym":10,"eligibilityCriteria":103,"healthyVolunteers":100,"sex":104,"minAge":105,"maxAge":10,"enrollmentInfo":106,"targetDuration":109,"studyType":110,"phases":10,"briefSummary":111,"conditions":112,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},{"fullName":5,"class":6},"Beijing Chao Yang Hospital","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"With immune checkpoint inhibitor-associated venous thromboembolism",null,"Patients with immune checkpoint inhibitor-associated venous thromboembolism would be included in this group",{"label":13,"type":10,"description":14,"interventionNames":10},"Without immune checkpoint inhibitor-associated venous thromboembolism","Patients without immune checkpoint inhibitor-associated venous thromboembolism would be included in this group",{"label":16,"type":10,"description":17,"interventionNames":10},"With immune checkpoint inhibitor-associated arterial thromboembolism","Patients with immune checkpoint inhibitor-associated arterial thromboembolism would be included in this group",{"label":19,"type":10,"description":20,"interventionNames":10},"Without immune checkpoint inhibitor-associated arterial thromboembolism","Patients without immune checkpoint inhibitor-associated arterial thromboembolism would be included in this group",[22],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Yuhui Zhang","CONTACT","86+13520108369","zhangyhcy@163.com",[28,46,60,68,78],{"facility":29,"status":30,"city":31,"state":32,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"The First Affiliated Hospital of Zhengzhou University","RECRUITING","Zhengzhou","Henan","China","CN",{"type":36,"coordinates":37},"Point",[38,39],113.64861,34.75778,{"lat":39,"lon":38},[42],{"name":43,"role":24,"phone":44,"phoneExt":10,"email":45},"Yanping Su","86+13938270842","suyanping2011@163.com",{"facility":47,"status":30,"city":48,"state":49,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"The Fourth Hospital of Inner Mongolia Autonomous Region","Hohhot","Inner Mongolia",{"type":36,"coordinates":51},[52,53],111.65222,40.81056,{"lat":53,"lon":52},[56],{"name":57,"role":24,"phone":58,"phoneExt":10,"email":59},"Jing Zhao","86+15540718272","171489419@qq.com",{"facility":61,"status":30,"city":62,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":63,"geoPoint":67,"contacts":10},"Beijing Chaoyang Hospital, Capital Medical University","Beijing",{"type":36,"coordinates":64},[65,66],116.39723,39.9075,{"lat":66,"lon":65},{"facility":69,"status":30,"city":62,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":70,"geoPoint":72,"contacts":73},"Beijing Luhe Hospital, Capital Medical University",{"type":36,"coordinates":71},[65,66],{"lat":66,"lon":65},[74],{"name":75,"role":24,"phone":76,"phoneExt":10,"email":77},"Yuan Yuan","86+18801266701","yuanyuaninternist@163.com",{"facility":79,"status":30,"city":62,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":80,"geoPoint":82,"contacts":83},"China-japan Friendship Hospital",{"type":36,"coordinates":81},[65,66],{"lat":66,"lon":65},[84],{"name":85,"role":24,"phone":86,"phoneExt":10,"email":87},"Meng Yang","86+18618307980","yangm_zoe@163.com",{"type":89,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[91,93,95,96],{"name":92,"class":6},"Capital Medical University",{"name":94,"class":6},"China-Japan Friendship Hospital",{"name":29,"class":6},{"name":47,"class":97},"UNKNOWN","100589152","development-and-application-of-a-thrombosis-risk-prediction-model-in-lung-cancer-patients-treated-with-immune-checkpoint-inhibitors-100589152",false,"NCT06950697","Development and Application of a Thrombosis Risk Prediction Model in Lung Cancer Patients Treated With Immune Checkpoint Inhibitors","Inclusion Criteria:\n\n* Age ≥18 years\n* Histopathologically confirmed lung cancer diagnosis at enrollment\n* Received at least one dose of a China-approved lung cancer immune checkpoint inhibitor\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Presence of two or more primary cancers\n* Missing data for key variables\n* Inability to comply with follow-up requirements\n* Presence of VTE\u002FATE at the time of ICI initiation","ALL","18 Years",{"count":107,"type":108},2400,"ESTIMATED","30 Months","OBSERVATIONAL","The purpose of this observational study is to explore the incidence, risk factors, and relationship with therapeutic outcomes of VTE (venous thromboembolism) and ATE (arterial thromboembolism) associated with immune checkpoint inhibitors (ICIs) therapy. The primary questions it aims to address are:\n\n1. What is the real-world incidence of VTE\u002FATE in lung cancer patients receiving immune checkpoint inhibitors?\n2. What are the risk factors and biomarkers for VTE\u002FATE in lung cancer patients receiving immune checkpoint inhibitors?\n3. What is the impact of VTE\u002FATE on the prognosis of lung cancer patients receiving immune checkpoint inhibitors?\n\nResearchers will compare the characteristics and biomarkers of patients with and without ICI-associated VTE\u002FATE to identify novel specific biomarkers for thrombotic events. Furthermore, they will construct a risk assessment model for thrombotic events to provide guidance for precision prevention and treatment in clinical practice.",[113,114,115,116],"Lung Cancer","Venous Thromboembolism","Arterial Thromboembolism","Immune Checkpoint Inhibitors (ICIs)","2026-04-26",{"date":119,"type":120},"2026-04-30","ACTUAL",{"date":122,"type":120},"2019-01-01",{"date":124,"type":108},"2027-12-01",{"name":5,"class":6},5]