[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581626":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Fu Jen Catholic University Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Reproductive Period",null,"Women aged 20-40 years with regular menstrual cycles, representing the reproductive stage.",[13],"Other: Blood Sample Collection",{"label":15,"type":10,"description":16,"interventionNames":17},"Perimenopausal Transition Period","Women aged 40-55 years have menstrual cycle within one year but experiencing menstrual irregularities, representing the transition into menopause.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Postmenopausal Period","Women aged 50 years and older who have not had a menstrual period for at least one year, representing the postmenopausal stage.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Blood Sample Collection","Collection of peripheral blood samples for mitochondrial analysis, including the extraction of mononuclear cells and plasma for further assessment of mitochondrial quality and quantity.",[15,19,9],[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Shu-Yu Liu","CONTACT","+886910893512","syliu0123@outlook.com",[34],{"facility":35,"status":36,"city":37,"state":10,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Fu Jen Catholic University Hospital, Fu Jen Catholic University","RECRUITING","New Taipei City","24352","Taiwan","TW",{"type":42,"coordinates":43},"Point",[44,45],121.45703,25.06199,{"lat":45,"lon":44},[48],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100581626","development-of-biomarkers-for-monitoring-menopause-in-women-100581626",false,"NCT06852755","Development of Biomarkers for Monitoring Menopause in Women","Inclusion Criteria:\n\n* Biological female, age order than 20 years old.\n\nExclusion Criteria:\n\n* Person with cancer.\n* Person with any known acute or chronic infection.\n* Person with known chronic illness under follow up or treatment.\n* Pregnancy, one year withing delivery, under breast feeding, or three months within breast feeding.\n* Under any female horemone therapy.",true,"FEMALE","20 Years",{"count":61,"type":62},100,"ESTIMATED","OBSERVATIONAL","This cross-sectional study aims to develop and validate mitochondrial biomarkers for monitoring menopause in women. The study will involve 100 participants divided into three groups: reproductive period, perimenopausal transition period, and postmenopausal period. Peripheral blood samples will be collected, and mitochondrial quality and quantity will be assessed using both qualitative and quantitative analyses. The study will identify potential biomarkers through metabolomics and validate them for monitoring the perimenopausal transition, providing a novel approach for women's health management during menopause.",[66,67],"Perimenopausal Biomarkers","Mitochondrial Biomarkers",[69,70,71,72],"Perimenopausal Transition","Mitochondria","Biomarker","Women's Health","2025-05-20",{"date":75,"type":76},"2025-05-25","ACTUAL",{"date":78,"type":76},"2024-07-30",{"date":80,"type":62},"2026-08",{"name":5,"class":6},1]