[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554591":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":29,"locations":35,"responsibleParty":65,"collaborators":28,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":28,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":28,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":38,"whyStopped":28,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"National Cancer Institute, Egypt","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal saline","ACTIVE_COMPARATOR","receiving erector spinae block with 27ml bupivacaine 0.25% + 3 ml NS",[13],"Procedure: ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%",{"label":15,"type":10,"description":16,"interventionNames":17},"magnesium sulphate 10%","receiving erector spinae block with 27 ml bupivacaine 0.25% + 3 ml magnesium sulphate 10%",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"dexamethasone","receiving erector spinae block with 27 ml bupivacaine 0.25% + 8 mg dexamethasone (2 ml) + 1 ml NS.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%","ESP block will be performed U\u002FS at the level of T 10 paraspinal level. The ultrasound transducer should be placed in the midline of the back at the desired level. The probe should then slowly be moved laterally until the transverse process is visible. The transverse process requires differentiation from the rib at that level.\n\nErector spinae muscle should be identified superficial to the transverse process. The needle inserted superior to the ultrasound probe in the cephalad to caudal direction. Once the needle tip is below the erector spinae muscle.\n\nThis separation from the transverse process confirms the proper needlemposition.\n\nThe local anesthetic should then be injected in 5 ml increments. The block will be performed preoperatively.",[9,19,15],null,[30],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Ahmed M Soliman","CONTACT","01286979695","ams21787arif@hotmail.com",[36],{"facility":37,"status":38,"city":39,"state":28,"zip":28,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"National Cancer institute - Cairo University","RECRUITING","Cairo","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.24967,30.06263,{"lat":46,"lon":45},[49,53,56,59,61,63],{"name":50,"role":32,"phone":51,"phoneExt":28,"email":52},"attef","0225328286","irb@nci.cu.edu.eg",{"name":54,"role":55,"phone":28,"phoneExt":28,"email":28},"Ahmed M soliman, lecturer","PRINCIPAL_INVESTIGATOR",{"name":57,"role":58,"phone":28,"phoneExt":28,"email":28},"kamal H Youssef, Dr","SUB_INVESTIGATOR",{"name":60,"role":58,"phone":28,"phoneExt":28,"email":28},"Noha M Abdelmoneim, lecturer",{"name":62,"role":58,"phone":28,"phoneExt":28,"email":28},"essam Mahran, profess",{"name":64,"role":58,"phone":28,"phoneExt":28,"email":28},"gehan kam, profess",{"type":55,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"Ahmed Mohamed Soliman","lecturer of anesthesia","100554591","dexamethasone-versus-mg-added-to-bupivacaine-used-in-espb-for-perioperative-pain-control-in-patients-undergoing-unilateral-nephrectomy-100554591",false,"NCT06501079","Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy","The Efficacy of Dexamethasone Versus Magnesium Sulphate Added to Bupivacaine Used in Erector Spinae Plane Block for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy","Inclusion Criteria:\n\n* Adult (18 - 65)\n* Patients undergoing unilateral nephrectomy\n* ASA II \u002F III\n\nExclusion Criteria:\n\n* Patient refusal\n* Age less than 18 years\n* Allergy to any of the studied medications\n* Mid line incision\n* Bilateral nephrectomy\n* Distorted anatomy of the back (e.g. kyphoscoliosis)\n* Known neurologic disorders, psychiatric disorder or chronic pain\n* Local infection\n* Hemodynamic instability","ALL","18 Years","65 Years",{"count":79,"type":80},78,"ESTIMATED","INTERVENTIONAL",[83],"NA","Aim of the study:\n\nThe current study aims to compare the effect of adding dexamethasone versus magnesium sulfate to bupivacaine in ultrasound-guided erector spinae plane block on the severity of postoperative pain.\n\nPrimary Objectives:\n\n\\- To compare the effect of ESPB without additives to the effect of adding dexamethasone and to the impact of adding magnesium sulfate in the form of post-operative morphine consumption",[86],"Renal Neoplasm",[88,89,90,91,92,93,94],"Dexamethasone","Magnesium Sulphate","Bupivacaine","Erector Spinae Plane Block","perioperative","pain control","unilateral nephrectomy","2024-07-11",{"date":97,"type":98},"2024-07-15","ACTUAL",{"date":100,"type":98},"2024-05-01",{"date":102,"type":80},"2024-12-01",{"name":5,"class":6},1]