[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611353":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":56,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Tam Anh Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Arm 1 - Dexmedetomidine + Desflurane (Intervention Group):\n\nDexmedetomidine bolus 1 µg\u002Fkg IV over 15 minutes before induction, followed by continuous infusion 0.5 µg\u002Fkg\u002Fh during surgery.\n\nDesflurane administered at 1 MAC with EtControl mode.",[13],"Drug: Dexmedetomidine + Desflurane",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","PLACEBO_COMPARATOR","Arm 2 - Desflurane + Normal Saline (Control Group):\n\nNormal saline infusion with identical timing and volume as the intervention group.\n\nDesflurane administered at 1 MAC with EtControl mode",[19],"Drug: Desflurane + Normal Saline",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Dexmedetomidine + Desflurane","Dexmedetomidine bolus 1 µg\u002Fkg IV over 15 minutes before induction, followed by continuous infusion 0.5 µg\u002Fkg\u002Fh during surgery.\n\nDesflurane administered at 1 MAC with EtControl mode.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Desflurane + Normal Saline","Normal saline infusion with identical timing and volume as the intervention group.\n\nDesflurane administered at 1 MAC with EtControl mode.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Phan Quoc Thai, MD","CONTACT","+84 964 152 360","thaipq@tahospital.vn",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Tam Anh TP. Ho Chi Minh General Hospital","RECRUITING","Ho Chi Minh City","Ho Chi Minh","700000","Vietnam","VN",{"type":47,"coordinates":48},"Point",[49,50],106.62965,10.82302,{"lat":50,"lon":49},[53],{"name":33,"role":34,"phone":26,"phoneExt":26,"email":36},{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[57],{"name":39,"class":6},"100611353","dexdes-trial-dexmedetomidine-desflurane-combination-in-laparoscopic-colectomy-100611353",false,"NCT07239479","DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy","Efficacy and Safety of Dexmedetomidine Combined With Desflurane in Laparoscopic Colectomy: A Randomized Double-Blind Controlled Clinical Trial (DEXDES Trial)","Inclusion Criteria:\n\n* Age 18-65 years\n* ASA Physical Status I-II\n* Elective laparoscopic colectomy\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Severe cardiac, hepatic, or renal disease\n* COPD or bronchial asthma\n* Chronic opioid or psychotropic medication use\n* Atrioventricular block (grade II-III), sick sinus syndrome\n* Significant intraoperative bleeding or hemodynamic instability","ALL","18 Years","65 Years",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.",[76],"Colorectal Neoplasms",[78,79,80,81,82,83],"Dexmedetomidine","Desflurane","General anesthesia","Colorectal surgery","ERAS","Hemodynamic stability","2025-12-28",{"date":86,"type":87},"2025-12-30","ACTUAL",{"date":89,"type":87},"2025-12-01",{"date":91,"type":70},"2027-01-30",{"name":5,"class":6},1]