[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582745":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":41,"locations":50,"responsibleParty":69,"collaborators":71,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":71,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":71,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":52,"whyStopped":71,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Fayoum University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Bolus group","EXPERIMENTAL","single dose 0.5 µg\u002Fkg in 15 ml saline over 10 min , started 15 minutes before end of surgery",[13],"Drug: Dexmedetomidine in 0.9 % NaCl 1,000 Mcg\u002F250 mL (4 Mcg\u002FmL) INTRAVEN INFUSION BOTTLE (ML)",{"label":15,"type":10,"description":16,"interventionNames":17},"Infusion group","Infusion of dexmedetomidine at a dose of 0.5 µg\u002Fkg\u002Fh without loading dose all through intraoperative time",[18],"Drug: Dexmedetomidine Injection [Precedex]",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Dexmedetomidine in 0.9 % NaCl 1,000 Mcg\u002F250 mL (4 Mcg\u002FmL) INTRAVEN INFUSION BOTTLE (ML)","An infusion given all through intraoperative time",[9],[26],"Dexmedetomidine infusion",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Dexmedetomidine Injection [Precedex]","Single dose given 15 minutes before end of surgery",[15],[32],"Dexmedetomidine bolus",[34,38],{"name":35,"affiliation":36,"role":37},"Yasser S Mostafa, MD","Fayoum University","PRINCIPAL_INVESTIGATOR",{"name":39,"affiliation":36,"role":40},"Mohamed A Shawky, MD","STUDY_CHAIR",[42,47],{"name":35,"role":43,"phone":44,"phoneExt":45,"email":46},"CONTACT","01010509735","+2","ysm03@fayoum.edu.eg",{"name":39,"role":43,"phone":48,"phoneExt":45,"email":49},"0 109 525 4547","mas14@fayoum.edu.eg",[51],{"facility":5,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Al Fayyum","Faiyum Governorate","63514","Egypt","EG",{"type":59,"coordinates":60},"Point",[61,62],30.8418,29.30995,{"lat":62,"lon":61},[65,67],{"name":66,"role":43,"phone":44,"phoneExt":45,"email":46},"Yasser S Mostafa, MD.",{"name":39,"role":43,"phone":68,"phoneExt":45,"email":49},"01095254547",{"type":37,"investigatorFullName":35,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":71,"oldOrganization":71},"Lecturer of Anesthesiology",null,"100582745","dexmedetomidine-and-agitation-after-nasal-surgery-100582745",false,"NCT06867302","Dexmedetomidine and Agitation After Nasal Surgery","Effectiveness of Single Bolus Versus Continuous Infusion of Dexmedetomidine in Mitigating Agitation in Adults Undergoing Nasal Surgery: a Prospective Randomized Trial","Inclusion Criteria:\n\n* American Society of Anesthesiologist (ASA) Ⅰ or II\n* Adults with body mass index (BMI) \\\u003C 30 Kg\u002Fm\n* Underwent elective nasal surgery.\n\nExclusion Criteria:\n\n* Significant comorbidity like hepatic, renal, or cardiac disease\n* Auditory impairment\n* Cognitive dysfunction\n* Substance abuse\n* Allergy to the studied medicines\n* Planned intensive care admission after the surgery.",true,"ALL","18 Years","50 Years",{"count":84,"type":85},50,"ESTIMATED","INTERVENTIONAL",[88],"NA","The main objective of study is to compare dexmedetomidine single bolus dose before extubation with continuous infusion as regards their efficacy in mitigating the incidence of emergence agitation in obese adults undergoing nasal surgery.",[91,92],"Nasal Disease","Agitation, Emergence",[94,95,96],"Dexmedetomidine","Emergence agitation","Nasal surgery","2025-03-05",{"date":99,"type":100},"2025-03-10","ACTUAL",{"date":102,"type":100},"2025-03-01",{"date":104,"type":85},"2025-10-01",{"name":5,"class":6},1]