[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635703":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":39,"centralContacts":44,"locations":50,"responsibleParty":65,"collaborators":30,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":30,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":30,"enrollmentInfo":78,"targetDuration":30,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":96,"overallStatus":53,"whyStopped":30,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Saint-Joseph University","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Dexmedetomidine-fentanyl DEX-FEN","ACTIVE_COMPARATOR","DEX-FEN group: received dexmedetomidine (loading dose 0.5 µg\u002Fkg over 10 minutes, followed by maintenance at 0.25µg\u002Fkg\u002Fh) and a single fentanyl bolus (1 µg\u002Fkg).",[13,14],"Drug: Dexmedetomidine (DEX)","Drug: Fentanyl (FEN)",{"label":16,"type":10,"description":17,"interventionNames":18},"Propofol-Fentanyl PRO-FEN","PRO-FEN group: received propofol (target-controlled infusion to achieve a Ramsay Sedation Score of 2-3 as much as possible) and a single fentanyl bolus (1 µg\u002Fkg).",[19,14],"Drug: Propofol (PRO)",{"label":21,"type":10,"description":22,"interventionNames":23},"DEX-PRO-FEN","DEX-PRO-FEN : received dexmedetomidine (loading dose 0.5 µg\u002Fkg over 10 minutes, followed by maintenance at 0.25µg\u002Fkg\u002Fh), propofol (target-controlled infusion to achieve a Ramsay Sedation Score of 2-3 as much as possible), with a single fentanyl bolus (1 µg\u002Fkg).",[13,19,14],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DRUG","Dexmedetomidine (DEX)","Dexmedetomidine (loading dose 0.5 µg\u002Fkg over 10 minutes, followed by maintenance at 0.25µg\u002Fkg\u002Fh).",[21,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Propofol (PRO)","Propofol (target-controlled infusion to achieve a Ramsay Sedation Score of 2-3 as much as possible).",[21,16],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Fentanyl (FEN)","Single fentanyl bolus (1 µg\u002Fkg).",[21,9,16],[40],{"name":41,"affiliation":42,"role":43},"Naji Abou Jalad, MD","Hotel Dieu de France Hospital, Beirut, Lebanon","STUDY_DIRECTOR",[45],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},"Rhea Nacouzi, MD","CONTACT","+961 3359528","rhea.nacouzi@net.usj.edu.lb",[51],{"facility":52,"status":53,"city":54,"state":30,"zip":30,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Hotel-Dieu de France","RECRUITING","Beirut","Lebanon","LB",{"type":58,"coordinates":59},"Point",[60,61],35.50157,33.89332,{"lat":61,"lon":60},[64],{"name":46,"role":47,"phone":48,"phoneExt":30,"email":49},{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Hicham Abou Zeid","Head of Anesthesiology and Critical Care","100635703","dexmedetomidine-and-propofol-for-sedation-in-cataract-surgery-100635703",false,"NCT07556133","Dexmedetomidine and Propofol for Sedation in Cataract Surgery.","Dexmedetomidine vs Propofol for Sedation in Cataract Surgery : a Prospective Randomized Controlled Trial.","Inclusion Criteria:\n\n* Adults undergoing cataract surgery\n\nExclusion Criteria:\n\n* Severe hepatic insufficiency\n* Third degree AV block\n* Patient refusal","ALL","18 Years",{"count":79,"type":80},1000,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this prospective, randomized, single-blinded is to learn if there is an ideal sedation protocol in cataract surgery in adults.\n\nThe main questions it aims to answer are:\n\n* Does the combination of Dexmedetomidine and Propofol affect significantly Ramsay sedation scale, compared to Dexmedetomidine and compared to Propofol?\n* How does each sedation protocol affect hemodynamics? (Heart rate and blood pressure)\n* Are respiratory events more common in a certain group?\n* Is the surgeon's satisfaction similar among groups?\n* Are adverse effects (bradycardia, hypotension, nausea) more common in a certain group?\n\nResearchers will compare 3 sedation protocols : Dexmedetomidine versus Propofol versus the combination of these 2 drugs and to see if one protocol is overall superior to the others. Fentanyl will also be used in all 3 sedation protocols.\n\nParticipants will :\n\n* Receive one of these three protocols\n* Be operated for one or both eyes\n* Monitored during the whole surgery and in the recovery room\n* Be evaluated by the Ramsay sedation scale by a trained Anesthesiologist or CRNA during surgery and in the recovery room Surgeons will be asked about how much they were satisfied.",[86,87,88,89,90,91,92,93,94,95],"Sedation","Cataract","Hemodynamic","Hemodynamic Changes","Dexmedetomidine","Propofol Dosage","Fentanyl","Bradycardia","Tachycardia","Nausea and Vomiting",[97,87,98,99,100],"Dexmedetomidine and propofol in cataract surgery","sedation","Dexmedetomidine in cataract surgery","Sedation for cataract surgery","2026-04-21",{"date":103,"type":104},"2026-04-29","ACTUAL",{"date":106,"type":104},"2025-11-09",{"date":108,"type":80},"2026-12-09",{"name":5,"class":6},1]