[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576512":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":28,"locations":38,"responsibleParty":54,"collaborators":18,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":78,"whyStopped":18,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Loma Linda University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Interventional Diet","EXPERIMENTAL","Subjects will follow a specified diet (low salt, limited caffeine, high potassium, low phosphate, and limited protein and carbohydrate intake along with adequate water intake) after 1 week of preconditioning for 12 months.",[13],"Other: Interventional Diet",{"label":15,"type":16,"description":17,"interventionNames":18},"Regular Diet","NO_INTERVENTION","Subjects will follow the diet they normally adhere to after 1 week of preconditioning.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":18},"Low salt, limited caffeine, high potassium, low phosphate, and limited protein and carbohydrate intake along with adequate water intake diet",[9],[24],{"name":25,"affiliation":26,"role":27},"Amir Abdipour, MD","Loma Linda University Health","PRINCIPAL_INVESTIGATOR",[29,35],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Niloufar Ebrahimi Ebrahimi, MD","CONTACT","909-558-4000","55885","Nebrahimi@llu.edu",{"name":36,"role":31,"phone":32,"phoneExt":18,"email":37},"Sayna Norouzi, MD","Snorouzi@llu.edu",[39],{"facility":26,"status":18,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Loma Linda","California","92354","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-117.26115,34.04835,{"lat":49,"lon":48},[52],{"name":25,"role":31,"phone":53,"phoneExt":18,"email":18},"909-202-0252",{"type":55,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100576512","di-pkd-a-pilot-trial-of-dietary-intervention-in-patients-with-autosomal-dominant-polycystic-kidney-disease-100576512",false,"NCT06786260","Di-PKD: A Pilot Trial of Dietary Intervention in Patients With Autosomal Dominant Polycystic Kidney Disease","Di-PKD: A Pilot Trial of a 12-Month Targeted Dietary Intervention on Cyst Progression in Patients With Autosomal Dominant Polycystic Kidney Disease","ADPKD","Inclusion Criteria:\n\n* Confirmed diagnosis of ADPKD\n* Genetic testing confirmation of PKD1 or PKD2\n* eGFR \\>30mL\u002F1.73m2\n* Willingness to adhere to a preconditioning diet for 1 week and ability to complete the study\n* Mayo Clinic Imaging Classification (MCIC): 1C, 1D, 1E\n\nExclusion Criteria:\n\n* History of dietary non-adherence\n* Subjects on Tolvaptan\n* Comorbidities that could interfere with participation (Diabetes, Heart Failure (EF\\\u003C30%) Advanced Chronic Kidney Disease (CKD) Stage 4 and higher)","ALL","18 Years","65 Years",{"count":68,"type":69},30,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this interventional study is to evaluate the impact of a specific diet (low salt, limited caffeine, high potassium, low phosphate, limited protein, limited carbohydrate intake, adequate water intake) on changes in serum and urinary biomarkers, total kidney volume (TKV), and cyst progression in subjects with autosomal dominant polycystic kidney disease (ADPKD).\n\nResearchers will compare the results of subjects in the study diet (interventional) arm to the results of subjects in the regular diet (control) arm.",[75],"Autosomal Dominant Polycystic Kidney Disease (ADPKD)",[62,77],"Diet","NOT_YET_RECRUITING","2026-01-28",{"date":81,"type":82},"2026-01-30","ACTUAL",{"date":84,"type":69},"2026-05",{"date":86,"type":69},"2027-04",{"name":5,"class":6},1]