[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627709":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":65,"centralContacts":70,"locations":10,"responsibleParty":79,"collaborators":81,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":99,"sex":100,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":10,"studyType":106,"phases":10,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":115,"whyStopped":10,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":10},{"fullName":5,"class":6},"Singapore General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Singaporeans of Asian ethnicity under 40 years",null,"Not previously known to have diabetes",[13,14,15,16,17,18,19,20,21,22],"Diagnostic Test: Oral glucose tolerance test and HbA1c","Other: Anthropometric measurements","Diagnostic Test: Body impedance Analysis","Diagnostic Test: Handgrip measurement","Diagnostic Test: Continuous glucose monitoring","Other: Food diary recording over days 2 and 3 of continuous glucose monitoring","Other: Survey","Other: Skin reaction information","Other: Download of social media data","Diagnostic Test: Whole genome sequencing",[24,29,33,37,41,45,49,53,57,61],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"DIAGNOSTIC_TEST","Oral glucose tolerance test and HbA1c","Following overnight fasting for 8 hours",[9],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"Anthropometric measurements","Body Mass Index, Waist-Hip ratio, Blood pressure",[9],{"type":25,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Body impedance Analysis","Body composition analysis",[9],{"type":25,"name":38,"description":39,"armGroupLabels":40,"otherNames":10},"Handgrip measurement","Handgrip strength measured using Jamar Dynanometer",[9],{"type":25,"name":42,"description":43,"armGroupLabels":44,"otherNames":10},"Continuous glucose monitoring","Use of Retrospective continuous glucose monitoring sensor (Freestyle Libre Pro IQ)",[9],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":10},"Food diary recording over days 2 and 3 of continuous glucose monitoring","Including written food records and photographs for all food and drink intake",[9],{"type":6,"name":50,"description":51,"armGroupLabels":52,"otherNames":10},"Survey","Retrieval of sociodemographic details, family history of diabetes and comorbid conditions, information on dietary intake, physical activity levels, and health seeking behaviour. This includes average daily step count for 7\u002F30 days.",[9],{"type":6,"name":54,"description":55,"armGroupLabels":56,"otherNames":10},"Skin reaction information","Form to feedback on any sensor skin reactions",[9],{"type":6,"name":58,"description":59,"armGroupLabels":60,"otherNames":10},"Download of social media data","This will involve a highly curated list of information to be retrieved from Facebook, Instagram and TikTok to enable AI-led sociobehavioural profiling. This will not retrieve any information on posts, photos, likes, comments, reactions or any item that will express intent.",[9],{"type":25,"name":62,"description":63,"armGroupLabels":64,"otherNames":10},"Whole genome sequencing","Whole blood sample will be retrieved and stored before being sent for whole genome sequencing at a later stage.",[9],[66],{"name":67,"affiliation":68,"role":69},"Daphne SL Gardner, BA, BMBCh(Oxon), MRCP (UK)","Singapore Health","PRINCIPAL_INVESTIGATOR",[71,76],{"name":72,"role":73,"phone":74,"phoneExt":10,"email":75},"Daphne SL Gardner, BA, BMBCh (Oxon), MRCP (UK)","CONTACT","+6563214654","daphne.gardner@singhealth.com.sg",{"name":77,"role":73,"phone":10,"phoneExt":10,"email":78},"Navreen Kaur","navreen.k.g.singh@singhealth.com.sg",{"type":80,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[82,85,87,89],{"name":83,"class":84},"SingHealth Duke-NUS Academic Medical Centre","UNKNOWN",{"name":86,"class":84},"Duke-NUS Centre of Quantitative Medicine",{"name":88,"class":84},"Data Science and Artificial intelligence Laboratory, SGH",{"name":90,"class":84},"Translational Research and Innovation Lab, SingHealth","100627709","diabetes-in-asians-at-risk-in-youth-100627709",false,"NCT07452159","Diabetes In Asians at Risk in Youth","Diabetes in Asians at Risk in Youth","DIARY","Inclusion Criteria:\n\n* Asian\u002FPart Asian ethnicity living in Singapore, not known to have diabetes\n\nExclusion Criteria:\n\n* Pregnancy women\n* Non-Asian ethnicity\n* On active cancer\u002Fsteroid therapy\n* Haemoglobinopathies or haemolytic anaemia\n* Previous bariatric surgery\n* Previous partial\u002Ftotal pancreatectomy",true,"ALL","21 Years","39 Years",{"count":104,"type":105},3000,"ESTIMATED","OBSERVATIONAL","This observational study aims to develop novel contemporary risk factor tools for detecting young onset diabetes (under 40y) in young Asians in Singapore. The investigators aim to recruit 3000 people not currently known to have diabetes, selected across age and Body Mass Index categories, and perform formal diagnostic tests for diabetes (oral glucose tolerance test and HbA1c). The participants will also undergo continuous glucose monitoring sensor, keep a food diary, and undergo body composition analysis using bioimpedance analysis, handgrip measurements for muscle strength, and sociobehavioural profiling through download of a curated list of social media interactions. The participants will also have a blood sample retrieved and stored for subsequent comparison between people with normal glucose versus abnormal glucose levels. The whole group will also have another blood sample stored for whole gene analysis.",[109],"Young Onset Asian Diabetes (Under 40 Years)",[111,112,113,114],"Young onset diabetes","Asian","Risk factors","contemporary","NOT_YET_RECRUITING","2026-03-01",{"date":118,"type":119},"2026-03-05","ACTUAL",{"date":121,"type":105},"2026-03-18",{"date":123,"type":105},"2029-01-02",{"name":5,"class":6}]