[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316365":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":22,"locations":27,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":10,"maxAge":54,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Guangzhou Women and Children's Medical Center","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"IUGR group",null,"Estimated fetal weight below10th percentile for gestational age associated with Abnormal Doppler flow in the umbilical cord (umbilical artery pulsatility index (PI)\\>95th percentile).",{"label":13,"type":10,"description":14,"interventionNames":10},"Structural anomaly group","Fetus\u002Fneonates\u002Finfants who are diagnosed as congenital malformations, deformations, disruptions, dysplasias by ultrasound.",{"label":16,"type":10,"description":17,"interventionNames":10},"Chromosomal anomaly group","Fetus\u002Fneonates\u002Finfants diagnosed by genetic amniocentesis or chorionic villus sampling for increased risk for fetal aneuploidy or fluorescence in situ hybridization.",[19],{"name":20,"affiliation":5,"role":21},"Wei Zhong, Master","PRINCIPAL_INVESTIGATOR",[23],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},"CONTACT","020-38076288","zhongwei@gwcmc.org",[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Guangzhou","Guangdong","510623","China","CN",{"type":36,"coordinates":37},"Point",[38,39],113.25,23.11667,{"lat":39,"lon":38},[42],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},{"type":21,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Wei Zhong","Director","100316365","diagnosis-and-management-of-intrauterine-growth-restriction-and-congenital-anomalies-100316365",false,"NCT03398629","Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies","Diagnosis and Management of Intrauterine Growth Restriction, Structural Anomalies and Chromosomal Anomalies: A Prospective Cohort Study","Inclusion Criteria:\n\nAll pregnant women who present to Guangzhou Women and Children's Medical Center meeting one of the following prenatal diagnoses and neonates\u002Finfants who are diagnosed as one of the following anomalies will be invited to participate:\n\n1. Intrauterine growth restriction (IUGR)\n2. Structural anomaly\n3. Chromosomal anomaly\n\nExclusion Criteria:\n\n1. Pregnant women who don't agree to participate;\n2. Pregnant women delivering babies at other hospitals.\n3. Prenatally suspected anomalies that are not confirmed by postnatal diagnosis.","ALL","18 Years",{"count":56,"type":57},10000,"ESTIMATED","20 Years","OBSERVATIONAL","The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses\u002Finfants with IUGR or congenital anomalies, which provide vital support and research foundation for accurate diagnosis, precision treatment and meticulous management.",[62,63,64,65],"Intrauterine Growth Restriction","Fetal Anomaly","Chromosomal Anomalies","Pregnancy","2019-06-03",{"date":68,"type":69},"2019-06-04","ACTUAL",{"date":71,"type":69},"2019-05-01",{"date":73,"type":57},"2038-03-01",{"name":5,"class":6},1]