[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100340714":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":30,"locations":36,"responsibleParty":51,"collaborators":55,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":10,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Herlev Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Low turnover bone disease",null,"PTH\\\u003C150 pg\u002Fml",[13],"Diagnostic Test: 18F-PET",{"label":15,"type":10,"description":16,"interventionNames":17},"High turnover bone disease","PTH\\>300 pg\u002Fml",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Normal renal function","Patients under examination for prostate cancer",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DIAGNOSTIC_TEST","18F-PET","Bone biopsy and 18F-PET",[15,9,19],[29],"Bone biopsy",[31],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Ditte Hansen, PhD","CONTACT","+4538683868","ditte.hansen.04@regionh.dk",[37],{"facility":5,"status":38,"city":39,"state":10,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Herlev","2730","Denmark","DK",{"type":44,"coordinates":45},"Point",[46,47],12.43998,55.72366,{"lat":47,"lon":46},[50],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Ditte Hansen","Associate professor",[56,58],{"name":57,"class":6},"University of Copenhagen",{"name":59,"class":6},"Universiteit Antwerpen","100340714","diagnosis-of-renal-osteodystrophy-in-patients-with-reduced-renal-function-100340714",false,"NCT03716128","Diagnosis of Renal Osteodystrophy in Patients With Reduced Renal Function","Diagnosis of Renal Osteodystrophy in Patients With Reduced Renal Function Can 18F-PET Replace Bone Histomorphometry","Patients with reduced renal function:\n\nInclusion Criteria:\n\n-≥ 18 years\n\n* estimated Glomerular Filtration Rate (eGFR) ≤ 20 ml\u002Fmin\u002F1,73m2\n* PTH \\\u003C 150 pg\u002Fml or PTH \\> 300 pg\u002Fml\n\nExclusion Criteria:\n\n* ongoing malignancy\n* Allergy towards tetracyclin\n* Pregnancy\n\nControl Group:\n\nInclusion Criteria:\n\n-≥ 18 years\n\n* eGFR \\>= 60 ml\u002Fmin\n* under examination for c prostata\n* Prostatic Specific Antigen (PSA) total \\\u003C40 µg\u002Fl\n\nExclusion:\n\n* Former kidney disease\n* ionized calcium or PTH outside normal range\n* Known metabolic bone disease\n* treatment with anticoagulants\n* Disturbed thrombosis and hemostasis","ALL","18 Years",{"count":70,"type":71},40,"ESTIMATED","OBSERVATIONAL","The aim of the study is to\n\n1. To describe the bone morphology in patients with reduced renal function and high or low parathyroid hormone (PTH) respectively.\n2. To investigate if the non-invasive method 18-Fluoride Positron Emission Tomography (18F-PET) can describe the bone turnover and reflect the bone histomorphologic changes\n3. To investigate if non-oxidized PTH reflects bone turnover",[75],"Renal Osteodystrophy","2025-03-14",{"date":78,"type":79},"2025-03-18","ACTUAL",{"date":81,"type":79},"2018-09-26",{"date":83,"type":71},"2027-10",{"name":53,"class":6},1]