[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609006":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":58,"collaborators":61,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":10,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":10,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Hangzhou Normal University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Disorders of consciousness",null,"Patients assessed as Minimally Conscious State plus\u002Fminus (MCS+\u002F-) and Unresponsive Wakefulness Syndrome (UWS) using the Coma Recovery Scale-Revised (CRS-R).",[13],"Device: Rectal Stimulation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Rectal Stimulation","The stimulation balloon was lubricated with paraffin oil and inserted until the distal end of the balloon was 10 cm from the anal verge, so as to eliminate the influence of different stimulation sites on the subjects.\n\nAt the start of stimulation, the dilatable balloon was rapidly inflated to 60\u002F80 mL, with a stimulation duration of 150 milliseconds. Concurrently with stimulation, the onset time of stimulation was marked on the electroencephalogram (EEG), and the time window for cortical potentials evoked by rapid rectal balloon distension stimulation was recorded. During the experiment, 35 stimulations were administered to the subjects; however, the first and last stimulations were excluded due to setup issues with the precision inflation-deflation control device for the intestinal balloon. Each stimulation was delivered as a 150-millisecond inflation pulse, providing 35 identical rectal stimulations. The inter-stimulus interval was randomly set to 12 ± 4 seconds, and EEG signals were",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"YiLin Zhao","CONTACT","18850147114","2567158152@qq.com",[27,48],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"The Second People's Hospital of Hefei","RECRUITING","Hefei","Anhui","230000","China","CN",{"type":36,"coordinates":37},"Point",[38,39],117.28083,31.86389,{"lat":39,"lon":38},[42,45],{"name":43,"role":23,"phone":44,"phoneExt":10,"email":25},"Yinliang QI","131099359067",{"name":46,"role":23,"phone":47,"phoneExt":10,"email":25},"Haibo Di","13588859929",{"facility":5,"status":49,"city":50,"state":51,"zip":52,"country":33,"countryCode":34,"cosmosGeoPoint":53,"geoPoint":57,"contacts":10},"ENROLLING_BY_INVITATION","Hangzhou","Zhejiang","310000",{"type":36,"coordinates":54},[55,56],120.16142,30.29365,{"lat":56,"lon":55},{"type":59,"investigatorFullName":22,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","PhD",[62],{"name":28,"class":63},"UNKNOWN","100609006","diagnosis-value-of-interoceptive-eeg-indicators-by-rectal-stimulation-in-doc-100609006",false,"NCT07208942","Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC","Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in Patients With Disorders of Consciousness","Inclusion Criteria:\n\n* Patients with non-acute Disorders of Consciousness (DoC) (disease course ≥ 28 days).\n* Aged 18 years or older.\n* No symptoms of fever, infection, or other similar conditions within 15 days.\n* No use of sedatives within 15 days.\n* No use of any drugs that may alter gastrointestinal motility within 7 days prior to testing.\n* Family members of participating patients have provided consent and signed the informed consent form.\n\nExclusion Criteria:\n\n* Patients with functional impairments caused by developmental psychiatric disorders or neurological diseases.\n* Patients with untreated epilepsy.\n* Untreated cerebral edema.\n* Patients with unstable vital signs.\n* A history of intestinal diseases.\n* A history of abdominal surgery other than simple appendectomy or simple cholecystectomy.\n* Organic diseases such as spinal cord injury, traumatic brain injury, and thyroid dysfunction.",true,"ALL","18 Years",{"count":75,"type":76},45,"ESTIMATED","OBSERVATIONAL","Study on the Significance and Value of Interoception-Related Indicators in the Classification of Patients with Disorders of Consciousness (DoC) via Rectal Stimulation",[80],"Disorders of Consciousness",[82,83,17,84],"Interoceptive","EEG","Diagnosis","2025-09-29",{"date":87,"type":88},"2025-10-06","ACTUAL",{"date":90,"type":88},"2024-12-01",{"date":92,"type":76},"2025-12",{"name":22,"class":6},2]