[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623664":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":10,"centralContacts":32,"locations":38,"responsibleParty":55,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":10,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":10,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Diquat Poisoning Group (Low Concentration)",null,"Participants presenting to the emergency department with clinically diagnosed acute diquat poisoning whose diquat concentration is classified into the low concentration stratum.",[13],"Device: Portable Mass Spectrometry Analysis System for Quantitative Diquat Detection (with Diquat Quantitative Detection Kit; In-Situ\u002FAmbient Ionization Mass Spectrometry Method)",{"label":15,"type":10,"description":16,"interventionNames":17},"Diquat Poisoning Group (Medium Concentration)","Participants presenting to the emergency department with clinically diagnosed acute diquat poisoning whose diquat concentration is classified into the medium concentration stratum.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Diquat Poisoning Group (High Concentration)","Participants presenting to the emergency department with clinically diagnosed acute diquat poisoning whose diquat concentration is classified into the high concentration stratum.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Non-Diquat Poisoning Group (Negative Control)","Participants presenting to the emergency department who are not diagnosed with acute diquat poisoning will be enrolled as negative controls. Their blood samples will be tested in parallel to support evaluation of method performance and to confirm negative results in non-diquat cases.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"DEVICE","Portable Mass Spectrometry Analysis System for Quantitative Diquat Detection (with Diquat Quantitative Detection Kit; In-Situ\u002FAmbient Ionization Mass Spectrometry Method)","The portable mass spectrometry analysis system is an in vitro diagnostic device used with a diquat quantitative detection kit based on an in-situ\u002Fambient ionization mass spectrometry method to quantify diquat concentrations in human blood samples. Whole blood specimens collected in routine clinical care will be analyzed using this device, and the quantitative results will be compared against those obtained using the reference standard method, liquid chromatography-tandem mass spectrometry (LC-MS\u002FMS), to evaluate analytical accuracy and agreement. Each specimen will be tested repeatedly (three measurements per sample), and the mean value will be used for statistical analysis. The study is observational and non-interventional, and test results generated by the portable mass spectrometry system are used for research evaluation purposes and do not alter routine clinical diagnosis or treatment decisions",[19,9,15,23],[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Hap Sun, MD, PhD","CONTACT","8613584017821","haosun_6@163.com",[39],{"facility":40,"status":10,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Nanjing Drum Tower Hospital","Nanjing","Jiangsu","210008","China","CN",{"type":47,"coordinates":48},"Point",[49,50],118.77778,32.06167,{"lat":50,"lon":49},[53],{"name":54,"role":35,"phone":36,"phoneExt":10,"email":37},"Hao Sun, MD, PhD",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hao Sun","Principal Investigator, Clinical Associate Professor","100623664","diagnostic-accuracy-of-a-diquat-quantitative-detection-kit-and-a-portable-mass-spectrometry-system-for-quantifying-diquat-concentrations-in-human-blood-samples-100623664",false,"NCT07399574","Diagnostic Accuracy of A Diquat Quantitative Detection Kit and A Portable Mass Spectrometry System for Quantifying Diquat Concentrations in Human Blood Samples","Accuracy, Safety, and Clinical Performance of a Diquat Quantitative Detection Kit (In-Situ Ionization Mass Spectrometry) and a Portable Mass Spectrometry System for Quantifying Diquat Concentrations in Human Blood Samples (Whole Blood\u002FPlasma)","Inclusion Criteria:\n\n1. Patients with suspected or clinically diagnosed acute diquat poisoning, providing whole blood and\u002For plasma samples, including qualified residual specimens retained after prior clinical testing when available.\n2. The participant or their legally authorized representative can fully understand the study purpose and procedures, voluntarily agrees to participate, and is willing and able to comply with the study requirements.\n3. Sample collection is performed according to routine clinical standards, with no apparent ethical concerns related to sample acquisition.\n\nExclusion Criteria:\n\n1. Abnormal sample appearance, such as visible flocculent material or other gross abnormalities.\n2. The participant is unable to provide a specimen, or the specimen does not meet testing requirements.\n3. Any participant considered inappropriate for inclusion by the investigator.","ALL",{"count":68,"type":69},60,"ESTIMATED","OBSERVATIONAL","This is an observational, non-interventional diagnostic accuracy study designed to evaluate a diquat quantitative detection kit (ambient ionization mass spectrometry method) and a portable mass spectrometry analysis system for measuring diquat concentrations in human blood samples (whole blood\u002Fplasma), using LC-MS\u002FMS as the clinical gold standard for comparison.",[73],"Diquat Poisoning","NOT_YET_RECRUITING","2026-05-24",{"date":77,"type":78},"2026-05-27","ACTUAL",{"date":80,"type":69},"2026-09-01",{"date":82,"type":69},"2028-12-31",{"name":5,"class":6},1]