[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100450335":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":25,"locations":34,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"History of colorectal adenomas group",null,"Subjects with known colorectal adenomas at the index colonoscopy",[13,14],"Diagnostic Test: M3","Diagnostic Test: FIT",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","M3","A panel of four bacterial gene markers (Fn, m3, Ch and Bc)",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"FIT","faecal immunochemical test",[9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Min Dai","CONTACT","+85260490760","mindai@link.cuhk.edu.hk",{"name":32,"role":28,"phone":29,"phoneExt":10,"email":33},"Connie Seto","waiyiseto@cuhk.edu.hk",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":10,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":10},"Prince of Wales Hospital","RECRUITING","Shatin","New Territories","Hong Kong","HK",{"type":43,"coordinates":44},"Point",[45,46],114.18333,22.38333,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Louis Ho Shing Lau","Resident Specialist","100450335","diagnostic-accuracy-of-m3-in-predicting-colorectal-advanced-adenoma-recurrence-m3-aa-100450335",false,"NCT05144152","Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)","A Prospective Study to Assess the Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) in Predicting Colorectal Advanced Adenoma Recurrence","M3-AA","Inclusion Criteria:\n\n1. Known colorectal adenomas during index colonoscopy;\n2. Available baseline M3 and FIT results before index colonoscopy;\n3. Aged ≥18 years old;\n4. Written informed consent obtained.\n\nExclusion Criteria:\n\n1. Refusal or unfit to undergo surveillance colonoscopy;\n2. Incomplete colonoscopy, incomplete removal of colorectal adenomas, or inadequate bowel preparation (defined as Boston Bowel Preparation Scale score 0 or 1 in any colonic segment) at index colonoscopy;\n3. Previous colonic resection;\n4. Personal history of colorectal cancer;\n5. Personal history of polyposis syndrome;\n6. Personal history of inflammatory bowel disease;\n7. Known pregnancy or lactation;\n8. Advanced comorbid conditions (defined as American Society of Anesthesiologists grade 4 or above);","ALL","18 Years",{"count":63,"type":64},600,"ESTIMATED","OBSERVATIONAL","The investigators aim to evaluate the diagnostic accuracy of FIT and the novel panel of four bacterial gene markers collectively named as M3, to detect recurrent advanced adenomas in patients with history of colonic adenomas.",[68,69,70],"Colorectal Adenoma","Advanced Adenoma","Colorectal Polyp",[22,72,73],"Bacterial marker","Colonoscopy","2024-08-26",{"date":76,"type":77},"2024-08-27","ACTUAL",{"date":79,"type":77},"2021-12-13",{"date":81,"type":64},"2025-06-15",{"name":5,"class":6},1]