[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624225":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":11,"locations":17,"responsibleParty":67,"collaborators":71,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":10,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":10,"enrollmentInfo":90,"targetDuration":93,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":10},"All Participants",null,[12],{"name":13,"role":14,"phone":15,"phoneExt":10,"email":16},"Maurizio S. Tonetti","CONTACT","15000102368","tonetti@hku.hk",[18,37,53],{"facility":19,"status":20,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine","RECRUITING","Shanghai","Shanghai Municipality","200000","China","CN",{"type":27,"coordinates":28},"Point",[29,30],121.45806,31.22222,{"lat":30,"lon":29},[33],{"name":34,"role":14,"phone":35,"phoneExt":10,"email":36},"Yaun Li, PhD","8615000102368","ly9919@hotmail.com",{"facility":38,"status":39,"city":40,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":48,"contacts":49},"Department of Oral and Maxillofacial Sciences, Policlinico Umberto I, affiliated to Sapienza University","NOT_YET_RECRUITING","Roma","06100","Italy","IT",{"type":27,"coordinates":45},[46,47],11.10642,44.99364,{"lat":47,"lon":46},[50],{"name":51,"role":14,"phone":10,"phoneExt":10,"email":52},"Lorenzo Marini, DMD PhD","lorenzo.marini@uniroma1.it",{"facility":54,"status":39,"city":55,"state":10,"zip":10,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Department of Periodontology, Guy's Hospital affiliated to King's College London","London","United Kingdom","UK",{"type":27,"coordinates":59},[60,61],-0.12574,51.50853,{"lat":61,"lon":60},[64],{"name":65,"role":14,"phone":10,"phoneExt":10,"email":66},"Luigi, Nibali","luigi.nibali@kcl.ac.uk",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Maurizio Tonetti","Professor",[72,74,76,78],{"name":73,"class":6},"University of Chieti",{"name":75,"class":6},"King's College London",{"name":77,"class":6},"University of Roma La Sapienza",{"name":79,"class":6},"University of Turin, Italy","100624225","diagnostic-accuracy-of-oral-images-opgs-biomarkers-and-questionnaires-vs-clinical-assessment-for-periodontal-disease-postnct07164573-100624225",false,"NCT07406867","Diagnostic Accuracy of Oral Images, OPGs, Biomarkers and Questionnaires vs. Clinical Assessment for Periodontal Disease (PostNCT07164573)","Diagnostic Accuracy of Oral Images, Orthopantomographs (OPGs), Biomarkers and Self-Reported Questionnaires vs. Clinical Assessment for Detecting Periodontal Health and Disease: a Multi-center Diagnostic Study","Inclusion Criteria:\n\n* Adult patients aged 18 years or older.\n* Seeking dental care at one of the participating study centers.\n* Ability to understand and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Edentulous patients (complete tooth loss).\n* Pregnancy or lactation.\n* History of periodontal therapy (other than supragingival prophylaxis\u002Fcleaning) within the past 12 months.\n* Use of antibiotic medication within the 3 months prior to enrollment.",true,"ALL","18 Years",{"count":91,"type":92},2000,"ESTIMATED","1 Day","OBSERVATIONAL","This multi-center, cross-sectional diagnostic trial evaluates the accuracy of multiple non-invasive screening tools-including self-reported questionnaires, intra-oral photographs, orthopantomographs (OPGs), intraoral scans (IOS), and salivary\u002Fmicrobial biomarkers-for detecting periodontal health and diseases (gingivitis and periodontitis Stages I-IV), using full-mouth clinical periodontal examination as the reference standard. A total of 2,000 participants will be recruited across five international centers. Diagnostic performance (sensitivity, specificity, AUROC) of individual and combined methods will be assessed using logistic regression and machine learning algorithms to establish an optimized multi-modal screening algorithm.",[97,98,99],"Periodontal Disease","Gingivitis","Periodontitis",[101,102,103,104,105,106],"Diagnosis","ArtiLcial Intelligence","Periodontal Diseases","Radiography","Machine Learning","Photography","2026-04-24",{"date":109,"type":110},"2026-04-30","ACTUAL",{"date":112,"type":110},"2026-03-01",{"date":114,"type":92},"2029-03-01",{"name":5,"class":6},3]