[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630502":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":12,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":12,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":12,"enrollmentInfo":61,"targetDuration":12,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":12,"overallStatus":33,"whyStopped":12,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Third Military Medical University","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"EBUS-TBNA","NO_INTERVENTION","Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) will be performed",null,{"label":14,"type":15,"description":16,"interventionNames":17},"EBUS-TBNA plus EBUS-TBMCB","EXPERIMENTAL","Following the completion of EBUS-TBNA, EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMCB) will be performed.",[18],"Procedure: EBUS-TBMCB",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","EBUS-TBMCB","Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy will be performed in experimental arm following EBUS-TBNA",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Hanbing Wang","CONTACT","+86 18885230175","18885230175@163.com",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Chongqing","Chongqing Municipality","400038","China","CN",{"type":40,"coordinates":41},"Point",[42,43],106.55771,29.56026,{"lat":43,"lon":42},[46],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":47},"18885230175@qq.com",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Ye Fan","Principal investigator","100630502","diagnostic-value-and-safety-of-combined-biopsy-for-mediastinal-metastasis-of-lung-cancer-100630502",false,"NCT07488507","Diagnostic Value and Safety of Combined Biopsy for Mediastinal Metastasis of Lung Cancer","Diagnostic Value and Safety of EBUS-TBNA Combined With Medaistinal Cryobiopsy for Mediastinal Metastasis of Lung Cancer","Inclusion Criteria:\n\n1. Aged ≥18 years;\n2. Presence of at least one mediastinal lesion (short-axis diameter ≥10 mm) confirmed by thin-slice chest CT;\n3. Patients who have not undergone prior mediastinal biopsy and require further mediastinal biopsy to confirm etiology or pathological subtype, meeting at least one of the following criterias:\n\n(1) suspected lung cancer diagnosed by two senior physicians; (2) confirmed lung cancer (requiring mediastinal staging); (3) recurrent lung cancer; 4.Patients must have completed all required preoperative laboratory tests and necessary examinations (e.g., cardiac ultrasound, CTA) to rule out contraindications; 5. Patients are informed and capable of providing written informed consent.\n\nExclusion Criteria:\n\n1. Presence of severe cardiopulmonary disease, coagulation disorders, massive hemoptysis, poor tolerance to anesthesia, or other contraindications related to bronchoscopy;\n2. Intraoperative endobronchial ultrasound exploration of the lesion failed to detect the target lesion despite \\> 20 minutes of attempts;\n3. Lesions identified as abscesses or cysts;\n4. Presence of mental illness, severe neurosis, or other conditions that preclude the provision of informed consent;\n5. Patients who have participated in other clinical trials within 3 months;\n6. Any other conditions considered to be inappropriate to be involved in this trial.","ALL","18 Years",{"count":62,"type":63},240,"ESTIMATED","INTERVENTIONAL",[66],"NA","The study is aimed o evaluate the diagnostic performance and treatment guidance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with transbronchial mediastinal cryobiopsy (EBUS-TBMCB) in patients with mediastinal metastases of lung cancer.",[69],"Mediastinal Metastases of Lung Cancer","2026-03-18",{"date":72,"type":73},"2026-03-23","ACTUAL",{"date":75,"type":63},"2026-03-20",{"date":77,"type":63},"2030-03-01",{"name":5,"class":6},1]