[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640470":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":35,"centralContacts":40,"locations":47,"responsibleParty":63,"collaborators":45,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":45,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":92,"whyStopped":45,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Universidad Pontificia de Salamanca","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Diaphragmatic Breathing Exercises Plus KOTS Currents","EXPERIMENTAL","Participants assigned to this arm will perform diaphragmatic breathing exercises combined with diaphragmatic electrostimulation using KOTS currents. The intervention will be delivered twice per week for three weeks. KOTS currents will be applied as medium-frequency alternating current stimulation, with stimulation intensity adjusted according to participant tolerance.",[13,14],"Device: Diaphragmatic Electrostimulation Using KOTS Currents","Behavioral: Diaphragmatic Breathing Exercises",{"label":16,"type":17,"description":18,"interventionNames":19},"Diaphragmatic Breathing Exercises","ACTIVE_COMPARATOR","Participants assigned to this arm will perform diaphragmatic breathing exercises twice per week for three weeks. Exercises will be performed in a supine position, with slow nasal inspiration and abdominal expansion followed by slow exhalation through pursed lips.",[14],[21,29],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Diaphragmatic Electrostimulation Using KOTS Currents","Diaphragmatic electrostimulation will be applied using KOTS currents, a medium-frequency alternating current stimulation. Electrodes will be placed over the seventh and eighth rib region along the mammillary line. Stimulation will be delivered in trains of 4 seconds of stimulation followed by 8 seconds of rest, with a carrier frequency of 2,500 Hz. The standard treatment duration will be 15 minutes: 10 minutes at 30 Hz followed by 5 minutes at 70 Hz. Stimulation intensity will be adjusted according to participant tolerance. The intervention will be delivered twice per week for three weeks, together with diaphragmatic breathing exercises.",[9],[27,28],"KOTS Currents","Russian Currents",{"type":30,"name":16,"description":31,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL","Participants will perform diaphragmatic breathing exercises in a supine position with the knees flexed. One hand will be placed on the chest and the other hand below the sternum. Participants will be instructed to inhale through the nose while expanding the abdomen with minimal thoracic movement, and to exhale slowly through pursed lips. The breathing pattern will include a 4-second inspiration and a 6-second expiration. Exercises will be performed twice per week for three weeks.",[16,9],[34],"Diaphragmatic Breathing",[36],{"name":37,"affiliation":38,"role":39},"Sara Perpiña-Martínez","Pontifical University of Salamanca","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"Sara Perpiña-Martinez","CONTACT","(+34) 910053661",null,"sperpinama@upsa.es",[48],{"facility":49,"status":45,"city":50,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Clínica Universitaria Salus Infirmorum, Universidad Pontificia de Salamanca","Madrid","28015","Spain","ES",{"type":55,"coordinates":56},"Point",[57,58],-3.70256,40.4165,{"lat":58,"lon":57},[61],{"name":62,"role":43,"phone":44,"phoneExt":45,"email":46},"Sara Perpiña Martínez",{"type":39,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":45,"oldOrganization":45},"Sara Perpiñá","Principal investigator and Professor of Physiotherapy","100640470","diaphragmatic-breathing-exercises-with-kots-currents-in-patients-with-long-covid-100640470",false,"NCT07621588","Diaphragmatic Breathing Exercises With KOTS Currents in Patients With Long COVID","Effects of Diaphragmatic Breathing Exercises Combined With Diaphragmatic Electrostimulation Using KOTS Currents in Patients With Long COVID: A Pilot Randomized Controlled Trial","KOTS-LC","Inclusion Criteria:\n\n* Men and women aged 18 to 65 years.\n* Medical diagnosis of Long COVID.\n* At least 2 months since SARS-CoV-2 infection.\n* Ability and willingness to provide informed consent.\n* Ability to participate in the assigned intervention and assessment procedures.\n\nExclusion Criteria:\n\n* Presence of a pacemaker.\n* History of epilepsy.\n* Pregnancy.\n* History of acute cardiac arrest.\n* Severe respiratory distress.\n* Use of a wheelchair.\n* Blurred vision.\n* Cyanosis.\n* Refusal to perform part or all of the treatment.\n* Incomplete or incorrectly completed questionnaires.","ALL","18 Years","65 Years",{"count":78,"type":79},10,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study will evaluate the effects of diaphragmatic breathing exercises combined with diaphragmatic electrostimulation using KOTS currents in patients with Long COVID. Participants will be randomly assigned to one of two groups. The control group will perform diaphragmatic breathing exercises, while the intervention group will perform diaphragmatic breathing exercises combined with diaphragmatic electrostimulation using KOTS currents. The intervention will last three weeks, with two sessions per week. The study will assess respiratory function, quality of life, physical function, dyspnea, fatigue, and basal oxygen saturation.",[85,86],"Long COVID Syndrome","Post-Acute COVID-19 Syndrome",[34,27,28,88,89,90,91],"Diaphragmatic Electrostimulation","Quality of Life","Respiratory Rehabilitation","Spirometry","NOT_YET_RECRUITING","2026-06-02",{"date":95,"type":96},"2026-06-04","ACTUAL",{"date":98,"type":79},"2026-06",{"date":100,"type":79},"2026-07",{"name":5,"class":6},1]