[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632389":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":11,"centralContacts":44,"locations":53,"responsibleParty":71,"collaborators":73,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":11,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":11,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":56,"whyStopped":11,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Centre Hospitalier Intercommunal Creteil","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"AABB (CF-CPAP; CF-CPAP;VF-CPAP;VF-CPAP)","EXPERIMENTAL",null,[13],"Device: CF-CPAP; CF-CPAP; VF-CPAP; VF-CPAP",{"label":15,"type":10,"description":11,"interventionNames":16},"BBAA (VF-CPAP; VF-CPAP;CF-CPAP;CF-CPAP)",[17],"Device: VF-CPAP; VF-CPAP; CF-CPAP; CF-CPAP",{"label":19,"type":10,"description":11,"interventionNames":20},"ABBA (CF-CPAP; VF-CPAP;VF-CPAP;CF-CPAP)",[21],"Device: CF-CPAP; VF-CPAP; VF-CPAP; CF-CPAP",{"label":23,"type":10,"description":11,"interventionNames":24},"BAAB (VF-CPAP; CF-CPAP;CF-CPAP;VF-CPAP)",[25],"Device: VF-CPAP; CF-CPAP; CF-CPAP; VF-CPAP",[27,32,36,40],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":11},"DEVICE","CF-CPAP; CF-CPAP; VF-CPAP; VF-CPAP","On day 1 : 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).\n\nOn day 2 : 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).",[9],{"type":28,"name":33,"description":34,"armGroupLabels":35,"otherNames":11},"VF-CPAP; VF-CPAP; CF-CPAP; CF-CPAP","On day 1 : 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).\n\nOn day 2 : 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).",[15],{"type":28,"name":37,"description":38,"armGroupLabels":39,"otherNames":11},"CF-CPAP; VF-CPAP; VF-CPAP; CF-CPAP","On day 1 : 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).\n\nOn day 2 : 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).",[19],{"type":28,"name":41,"description":42,"armGroupLabels":43,"otherNames":11},"VF-CPAP; CF-CPAP; CF-CPAP; VF-CPAP","On day 1 : 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).\n\nOn day 2 : 2 hours of Constant Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording) then 2 hours of Variable Flow CPAP (30 minutes wash out then 1 hour 30 minutes recording).",[23],[45,50],{"name":46,"role":47,"phone":48,"phoneExt":11,"email":49},"Xavier DURRMEYER, MD, PhD","CONTACT","0157023468","Durrmeyer.xavier@chicreteil.fr",{"name":51,"role":47,"phone":11,"phoneExt":11,"email":52},"Anatole DECAIX, MD","Anatole.decaix@chicreteil.fr",[54],{"facility":55,"status":56,"city":57,"state":11,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Centre Hospitalier Intercommunal de Créteil","RECRUITING","Créteil","94000","France","FR",{"type":62,"coordinates":63},"Point",[64,65],2.46569,48.79266,{"lat":65,"lon":64},[68,70],{"name":46,"role":47,"phone":48,"phoneExt":11,"email":69},"xavier.durrmeyer@chicreteil.fr",{"name":51,"role":47,"phone":11,"phoneExt":11,"email":52},{"type":72,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[74],{"name":75,"class":76},"Pr Xavier DURRMEYER","UNKNOWN","100632389","diaphragmatic-swing-according-to-cpap-flow-output-in-neonates-disconeo-100632389",false,"NCT07513051","DIaphragmatic Swing According to Cpap Flow Output in NEOnates (DISCONEO)","Diaphragmatic Activity During Constant or Variable Flow CPAP in Neonates: a Non-inferiority, Randomized, Alternating Treatments Trial","Above mentioned age limits (72 hours to 10 weeks) apply to postnatal age. Inclusion criteria apply to gestational age at birth and postmenstrual age (in weeks).\n\nInclusion Criteria:\n\n* Neonates born at ≤ 32 weeks GA (gestational age)\n* Hospitalized in our tertiary hospital NICU (Neonatal intensive care unit)\n* Receiving CPAP since \\> 24 hours at inclusion\n* Equipped with EAdi catheters.\n* Aged more than 72 hours\n* With parental consent\n* Affiliated to or benefiting from a social security system\n\nNon inclusion Criteria:\n\n* More than 1 episode of apnea \u002F hour and\u002For hypercapnic acidosis (defined as pH \\\u003C 7.20 and\u002For pCO2 \\> 65)\n* FiO2 \\> 60%\n* Neonatal ARDS (acute respiratory distress syndrome) according to the Montreux definition\n* Pneumothorax\u002F pneumomediastinum\n* Nasal lesions contraindicating nasal noninvasive ventilation\n* Major congenital malformation\u002FChromosomopathies\n* Congenital neuromuscular diseases\n* Hemodynamic instability","ALL","72 Hours","10 Weeks",{"count":88,"type":89},20,"ESTIMATED","INTERVENTIONAL",[92],"NA","The hypothesis behind the study is that the performance of constant flow CPAP (Continuous Positive Airway Pressure) devices (CF-CPAP) is not inferior to that of variable flow CPAP devices (VF-CPAP) in terms of respiratory efforts assessed by swing EAdi (Electrical activity of diaphragm) in a population of premature neonates born ≤ 32 weeks of gestational age.",[95],"Neonatal Respiratory Distress",[97,98,99,100,101,102],"Continuous Positive Airway Pressure (CPAP)","Variable flow Continuous Positive Airway Pressure (VF-CPAP)","Constant flow Continuous Positive Airway Pressure (CF-CPAP)","Respiratory Effort","Infant comfort","Diaphragmatic electrical activity (EADi)","2026-06-22",{"date":105,"type":106},"2026-06-23","ACTUAL",{"date":108,"type":106},"2026-06-10",{"date":110,"type":89},"2027-12-12",{"name":5,"class":6},1]