[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100371855":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":20,"locations":30,"responsibleParty":50,"collaborators":52,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":19,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":19,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":19,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Mount Sinai Hospital, Canada","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ulcerative colitis patients with mild to moderate activity","EXPERIMENTAL","Participants will be followed for 14 days on their traditional diet followed by an 8 week intervention with the specially designed and provided treatment diet.",[13],"Other: UC intervention diet",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"UC intervention diet","The treatment diet has been designed based on the literature with the goal of influencing the biodiversity and density of the microbiome. All food through the duration of the 8 week dietary intervention period of the study will be provided to the treatment arm study participants.",[9],null,[21,27],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},"Jenny Lee","CONTACT","4165864800","2318","jenny.lee@sinaihealth.ca",{"name":28,"role":23,"phone":19,"phoneExt":19,"email":29},"Joanne Stempak","joanne.stempak@sinaihealth.ca",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Mount Sinai Hospital","RECRUITING","Toronto","Ontario","M5G 1X5","Canada","CA",{"type":40,"coordinates":41},"Point",[42,43],-79.39864,43.70643,{"lat":43,"lon":42},[46,47],{"name":22,"role":23,"phone":24,"phoneExt":25,"email":26},{"name":48,"role":49,"phone":19,"phoneExt":19,"email":19},"Mark S Silverberg, MD","PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[53],{"name":54,"class":55},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100371855","diet-intervention-treatment-for-active-ulcerative-colitis-100371855",false,"NCT04121806","Diet Intervention Treatment for Active Ulcerative Colitis","Diet Intervention as a Prebiotic Treatment for Active Ulcerative Colitis","Inclusion Criteria:\n\n* • Females and Males between the ages of 18 - 75 years of age at the time of enrolment\n\n  * Must have established diagnosis of UC by standard endoscopic, radiographic, or histological criteria\n  * Must have active UC defined by having a Mayo score equal to or greater than 2 within two months prior to enrollment\n  * Must have had \\> 10cm involvement at some point in their disease history\n  * FCP\\>250 or active endo within 6 months\n  * If a smoker, must not change smoking habits (frequency) during the course of the study\n  * If receiving medical therapy, no baseline therapy change within 4 weeks of study initiation and no change during the course of the study\n\nExclusion Criteria:\n\n* • Uncontrolled inflammation which will likely require surgery or escalation of therapy within 4 weeks of enrollment\n\n  * Pregnant or lactating females\n  * Allergy or intolerance to key or a great number food components of the study diet\n  * Current NSAID use\n  * Diagnosed with PSC\n  * Using topical therapies or suppositories\n  * Antibiotic use within 4 weeks of the study enrollment or during the study\n  * Confirmed C. difficile infection within 3 months of recruitment;\n  * Diagnosis of primary PSC;\n  * Currently using topical therapies or suppositories\n  * History of dysplasia or colorectal neoplasia.","ALL","18 Years","75 Years",{"count":67,"type":68},20,"ESTIMATED","INTERVENTIONAL",[71],"NA","The purpose of this study is to determine if a sustainable non-elemental diet can be used as a probiotic tool to alter the dysbiotic microbiome found in individuals with ulcerative colitis and thereby decrease disease activity.",[74],"Colitis, Ulcerative","2025-09-23",{"date":77,"type":78},"2025-09-29","ACTUAL",{"date":80,"type":78},"2021-03-01",{"date":82,"type":68},"2026-09-30",{"name":5,"class":6},1]