[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637416":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":11,"centralContacts":11,"locations":35,"responsibleParty":56,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":11,"eligibilityCriteria":65,"healthyVolunteers":62,"sex":66,"minAge":67,"maxAge":11,"enrollmentInfo":68,"targetDuration":11,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":11,"overallStatus":38,"whyStopped":11,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Medical University of Silesia","OTHER",[8,12,18,23],{"label":9,"type":10,"description":11,"interventionNames":11},"Standard medical care","NO_INTERVENTION",null,{"label":13,"type":14,"description":15,"interventionNames":16},"Resistance Exercise Training","EXPERIMENTAL","Elastic resistance bands and structured exercise education provided by a medical rehabilitation specialist.",[17],"Behavioral: Resistance Exercise",{"label":19,"type":14,"description":20,"interventionNames":21},"Dietary Intervention","Individualized 14-day meal plan based on the DASH diet with high-protein components.",[22],"Behavioral: Dietary Intervention",{"label":24,"type":14,"description":25,"interventionNames":26},"Combined Dietary and Exercise Intervention","Combination of dietary counseling and resistance exercise training as described above.",[17,22],[28,33],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"BEHAVIORAL","Resistance Exercise","The exercise intervention includes resistance training using elastic bands, with instruction and follow-up provided by a medical rehabilitation specialist.",[24,13],{"type":29,"name":19,"description":20,"armGroupLabels":34,"otherNames":11},[24,19],[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"2nd Department and Clinical Ward of Cardiology Specialist Hospital in Zabrze, Poland","RECRUITING","Zabrze","Silesian Voivodeship","41-800","Poland","PL",{"type":45,"coordinates":46},"Point",[47,48],18.78576,50.32492,{"lat":48,"lon":47},[51],{"name":52,"role":53,"phone":54,"phoneExt":11,"email":55},"Andrzej Tomasik PhD Andrzej Tomasik","CONTACT","+48 32 271 10 10","atomasik@sum.edu.pl",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Andrzej Tomasik MD PhD FESC","Associate Professor","100637416","dietary-intervention-and-physical-activity-in-patients-with-heart-failure-and-reduced-ejection-fraction-100637416",false,"NCT07595809","Dietary Intervention and Physical Activity in Patients With Heart Failure and Reduced Ejection Fraction","Inclusion Criteria:\n\nWritten informed consent obtained prior to participation Age \\>30 years Diagnosis of chronic heart failure, NYHA functional class I-III Left ventricular ejection fraction \\\u003C40%\n\nExclusion Criteria:\n\nNYHA functional class IV heart failure Potentially reversible cause of heart failure Estimated glomerular filtration rate \\\u003C30 mL\u002Fmin Severe anemia (hemoglobin \\\u003C9 g\u002FdL) Uncontrolled thyroid disease Severe hepatic dysfunction History of hyperkalemia or hyperkalemia at baseline Epilepsy Presence of joint endoprostheses Gastrointestinal disorders limiting adherence to the DASH diet Physical limitations precluding participation in structured exercis","ALL","30 Years",{"count":69,"type":70},100,"ESTIMATED","INTERVENTIONAL",[73],"NA","Heart failure with reduced ejection fraction (HFrEF) is frequently associated with abnormalities in body composition, including reduced skeletal muscle mass and sarcopenia, which are independent predictors of reduced exercise tolerance, impaired quality of life, and increased mortality. Despite advances in pharmacological therapy, evidence-based non-pharmacological strategies aimed at preventing muscle mass loss remain limited.\n\nThis randomized controlled trial aims to evaluate the effects of dietary intervention based on the DASH diet with high-protein elements, resistance exercise training, and their combination on skeletal muscle mass, functional capacity, echocardiographic parameters, biochemical markers, and quality of life in patients with HFrEF.",[76],"Heart Failure With Reduced Ejection Fraction","2026-05-13",{"date":79,"type":80},"2026-05-19","ACTUAL",{"date":82,"type":80},"2023-05-08",{"date":84,"type":70},"2027-04",{"name":5,"class":6},1]