[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558150":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":40,"responsibleParty":59,"collaborators":18,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":21,"officialTitle":21,"acronym":18,"eligibilityCriteria":66,"healthyVolunteers":64,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"National University of Singapore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","Throughout the 2-month intervention period, only participants in the intervention arm will be provided with bento-styled meals for lunch and dinner daily. The meals will encompass a variety of nutrient-rich ingredients, including whole grains, lean proteins, an array of fruits and vegetables, and healthy fats. The food will be prepared by a licensed food catering service.",[13],"Other: Dietary Intervention on Atopy",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","The control group will not receive the meals provided by our study nor will they receive any nutritional advice. Instead, they will continue following their usual dietary habits and patterns throughout the study period.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Dietary Intervention on Atopy","The primary aim of this dietary intervention study is to assess the effectiveness of a dietary pattern characterized by lower saturated fats, higher wholegrains, fruit, and vegetables in reducing the severity of AD in young Singapore adults, as measured by changes in Scoring Atopic Dermatitis (SCORAD) scores, over a 2-month intervention period.",[9],[25],{"name":26,"affiliation":27,"role":28},"Fook Tim CHEW, PhD","NUS Singapore","PRINCIPAL_INVESTIGATOR",[30,36],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Mei Hui Liu, PhD","CONTACT","65163523","(+65)","fstlmh@nus.edu.sg",{"name":37,"role":32,"phone":38,"phoneExt":34,"email":39},"Jun Jie Lim, PhD","65161685","limjj@nus.edu.sg",[41],{"facility":5,"status":42,"city":43,"state":43,"zip":44,"country":43,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Singapore","118177","SG",{"type":47,"coordinates":48},"Point",[49,50],103.85007,1.28967,{"lat":50,"lon":49},[53,55],{"name":37,"role":32,"phone":38,"phoneExt":54,"email":39},"+65",{"name":56,"role":32,"phone":57,"phoneExt":18,"email":58},"Nur Hafizah Binte Mohamed Yusri, MSc.","6594558400","hafizahy@nus.edu.sg",{"type":28,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"CHEW Fook Tim","Associate Professor","100558150","dietary-intervention-on-atopy-100558150",false,"NCT06547372","Inclusion Criteria:\n\n1. Presence of current, mild-to-moderate atopic dermatitis\u002Feczema at flexural areas\n2. 21 to 65 years of age (inclusive) at screening\n3. Must be English-literate and able to give informed consent in English\n4. Be residing in Singapore and will not be travelling outside of Singapore during the study period\n5. Reliable and willing to follow study procedures and be available for the duration of the study\n6. Non-smokers (tobacco and e-cigarette)\n7. Non-drinker (no regular or frequent consumption of alcohol)\n8. Overtly healthy with no pre-existing medical conditions (e.g., diabetes, hypertension, cancer, blood disorders, degenerative\u002Fliver\u002Fautoimmune\u002Fimmune\u002Frenal diseases, or psychiatric conditions)\n9. No food allergies to test foods\n10. No needle phobia\n11. Be willing to follow the instruction provided by the investigators on the use of any moisturiser, cosmetics, and\u002For topical cream on the skin throughout the entire duration of the study.\n\nExclusion Criteria:\n\n1. Concurrent participation in other research studies\n2. Pregnancy or lactating individuals\n3. Known or ongoing psychiatric disorders within 3 years\n4. Known severe nutritional deficiency\n5. Vegetarian\u002Fvegans (as meat will be included in the diet)\n6. Individuals who made a significant dietary change in the past 12 months\n7. Having a pre-existing dietary restriction that would interfere with the adherence to a whole diet meal\n8. Regular use of strong medication (western and\u002For traditional), therapies, and alternative medications\n9. Regular nutritional supplements in the past 12 months Regular consumption of oral contraceptive pills and\u002For steroid hormones\n10. Antibiotic use in the past 2 months\n11. Any long-term hospitalisation or surgery during the 6 months before enrolment in study\n12. Significant change in weight (+\u002F- 5.0%) during the past month\n13. History of bleeding diathesis or coagulopathy (or any bleeding disorders)\n14. Having donated blood of more than 500 mL within 4 weeks of study enrolment","ALL","21 Years","65 Years",{"count":71,"type":72},110,"ESTIMATED","INTERVENTIONAL",[75],"NA","Diet is a key determinant of overall health, with growing evidence associating dietary patterns with allergic diseases. Among these, atopic dermatitis (AD) is of particular interest as it often represents the earliest manifestation of the atopic triad. Investigating dietary interventions in AD therefore provides a relevant model to better understand how diet may influence the onset and progression of allergic disease more broadly.",[78,79,80,81],"Atopic Dermatitis","Atopic","Allergic Diseases","Allergic Rhinitis",[83,84,85,86,87,88,89,90,91,92,43,93],"Atopic dermatitis","My Healthy Eating Plate","eczema","healthy diet","diet","meals","foods","allergic","allergy","atopic","nutrients","2026-03-26",{"date":96,"type":97},"2026-04-01","ACTUAL",{"date":99,"type":97},"2024-05-10",{"date":101,"type":72},"2027-12-31",{"name":5,"class":6},1]