[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100446240":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":41,"responsibleParty":73,"collaborators":76,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":24,"enrollmentInfo":89,"targetDuration":24,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":44,"whyStopped":24,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of Manitoba","OTHER",[8,14],{"label":9,"type":6,"description":10,"interventionNames":11},"Liberalized dietary potassium and then restricted potassium via fruit and vegetables","Participants will receive weekly supplementation of higher potassium fruit and vegetables via grocery home delivery during the liberalized dietary potassium 2-week run-in and liberalized potassium treatment period, then cross-over to the restricted potassium treatment period following a 2-week washout period. Participants will receive a 30-60 minute dietary counseling session in the first week of each treatment period from a registered dietitian (RD), either in person or via videoconference, depending on regional Coronavirus disease (COVID)-19 restrictions and participant preference, which will outline the concepts of the dietary intervention. The RD will also recommend the best ways to prepare and include the fruit and vegetables into the participant's current diet.",[12,13],"Dietary Supplement: Liberalized dietary potassium via fruits and vegetables","Dietary Supplement: Standard dietary potassium restriction",{"label":15,"type":6,"description":16,"interventionNames":17},"Restricted dietary potassium and then liberalized potassium via fruit and vegetables","Participants will receive weekly supplementation of higher potassium fruit and vegetables via grocery home delivery during the liberalized dietary potassium 2 week run-in and then start receiving a restricted potassium treatment period, then cross-over to the liberalized potassium treatment period following a 2-week washout period. Participants will receive a 30-60 minute dietary counseling session in the first week of each treatment period from a registered dietitian (RD), either in person or via videoconference, depending on regional COVID-19 restrictions and participant preference, which will outline the concepts of the dietary intervention. The RD will also recommend the best ways to prepare and include the fruit and vegetables into the participant's current diet",[12,13],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DIETARY_SUPPLEMENT","Liberalized dietary potassium via fruits and vegetables","On the liberalized dietary potassium intervention, participants will receive groceries delivered to their houses that contain potassium rich fruit and vegetables, that contain more than 250 mg of potassium per typical serving. Participants will be instructed to incorporate the fruit and vegetables into their diet targeting a daily intake of 2000 mg of potassium a day from delivered fruit and vegetables, and a daily dietary potassium intake of 3500 mg.",[9,15],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Standard dietary potassium restriction","Participants will receive weekly supplementation of lower potassium fruit and vegetables, that deliver less than 200 mg of potassium per typical serving. Participants will be instructed to incorporate the fruit and vegetables into their diet targeting a daily intake of 500 mg of K a day from the box, and a daily dietary K intake \\\u003C 2000 mg. Participants will receive counselling from a registered dietician (RD) to reinforce the potassium restriction.",[9,15],[30],{"name":31,"affiliation":5,"role":32},"Dylan Mackay, PhD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","2042723119","dylan.mackay@umanitoba.ca",{"name":39,"role":35,"phone":24,"phoneExt":24,"email":40},"Rebecca Mollard, PhD","rmollard@sogh.mb.ca",[42,62],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Seven Oaks General Hospital Chronic Disease Innovation Centre","RECRUITING","Winnipeg","Manitoba","R2V 3M3","Canada","CA",{"type":51,"coordinates":52},"Point",[53,54],-97.14704,49.8844,{"lat":54,"lon":53},[57,58,59],{"name":39,"role":35,"phone":24,"phoneExt":24,"email":40},{"name":31,"role":32,"phone":24,"phoneExt":24,"email":24},{"name":60,"role":61,"phone":24,"phoneExt":24,"email":24},"Navdeep Tangri, MD, PhD","SUB_INVESTIGATOR",{"facility":63,"status":44,"city":45,"state":46,"zip":64,"country":48,"countryCode":49,"cosmosGeoPoint":65,"geoPoint":67,"contacts":68},"Health Sciences Centre","R3A 1R9",{"type":51,"coordinates":66},[53,54],{"lat":54,"lon":53},[69],{"name":70,"role":35,"phone":71,"phoneExt":24,"email":72},"Jay Hingwala, MD","204-787-3863","jhingwala@hsc.mb.ca",{"type":32,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Dylan MacKay","Assistant Professor",[77],{"name":78,"class":6},"Dalhousie University","100446240","dietary-potassium-liberalization-in-pre-dialysis-patients-100446240",false,"NCT05090865","Dietary Potassium Liberalization in Pre-Dialysis Patients","Dietary Potassium Liberalization With Fruit and Vegetables Versus Potassium Restriction in People With Chronic Kidney Disease (DK-Lib CKD) Trial","DK-LIB","Inclusion Criteria:\n\n* Male or female, aged 18 years or above\n* Participants who have an estimated glomerular filtration rate between 15 and 45 ml\u002Fmin\u002F1.73m2\n* Serum potassium concentration between 4.5 and 5.5 milliequivalent (mEq)\u002FL\n* Hemoglobin A1c ≤ 11%\n* Systolic and diastolic blood pressure \\<160\u002F100 mmHg\n* Are registered in the multidisciplinary nephrology clinic in Winnipeg\n* Able to communicate in English and provide written informed consent\n\nExclusion Criteria:\n\n* Serum potassium concentration \\> 5.6 mEq\u002FL, anuria, dialysis, or acute kidney injury failure in the 6 months prior to screening\n* Chronic obstructive pulmonary disease that requires the participant to be on oxygen\n* New York Heart Association Class 3-4 Heart symptoms or heart, liver or renal transplant\n* A myocardial infarction or stroke within the last 6 months\n* Unable to consume study treatments or control, such as swallowing or gastro-intestinal issues\n* Currently on potassium binding therapy\n* In the opinion of the investigator any medical condition, uncontrolled systemic disease or concurrent illness that would decrease the study compliance or jeopardize the safety of the participant\n* Female participant who is pregnant or lactating","ALL","18 Years",{"count":90,"type":91},30,"ESTIMATED","INTERVENTIONAL",[94],"NA","The study will look at the impact of the potassium content in fruits and vegetables, on serum potassium concentrations in people with Chronic Kidney Disease (CKD) using a randomized crossover design. Participants will receive home delivery of fruit and vegetables with either higher or lower potassium content in a random order. Clinical chemistry markers from blood and urine samples, blood pressure, physical functioning and health related quality of life will be assessed throughout the duration of the trial. This study will also measure their physical functioning, using a chair stand test. The results of this study could change the dietary recommendations for people with CKD related to potassium.",[97,98],"Chronic Kidney Disease","Hyperkalemia",[100,101],"Potassium","Nutrition","2026-01-14",{"date":104,"type":105},"2026-01-16","ACTUAL",{"date":107,"type":105},"2024-01-15",{"date":109,"type":91},"2026-05-31",{"name":5,"class":6},2]