[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642184":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":26,"responsibleParty":46,"collaborators":7,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":7,"enrollmentInfo":59,"targetDuration":7,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"The Cleveland Clinic","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"BEHAVIORAL","Limiting Ultraprocessed Food (UPF) in Diet","Participants in this study will be advised on ways to limit UPF in their diet for a period of 28 days. There is no specific diet to follow. Instead, researchers will ask participants to track what they eat in a mobile app (Cronometer) with the aim of reducing UPF consumption.",[14],{"name":15,"affiliation":5,"role":16},"W. H. Wilson Tang, MD","PRINCIPAL_INVESTIGATOR",[18,23],{"name":19,"role":20,"phone":21,"phoneExt":7,"email":22},"Valesha Province, MS","CONTACT","216-636-6153","provinv@ccf.org",{"name":24,"role":20,"phone":21,"phoneExt":7,"email":25},"Jennifer Wilcox","kirsopj@ccf.org",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Cleveland Clinic Main Campus","RECRUITING","Cleveland","Ohio","44195","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-81.69541,41.4995,{"lat":39,"lon":38},[42,43,45],{"name":19,"role":20,"phone":21,"phoneExt":7,"email":22},{"name":44,"role":20,"phone":21,"phoneExt":7,"email":25},"Jeniffer Wilcox",{"name":15,"role":16,"phone":7,"phoneExt":7,"email":7},{"type":16,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Wilson Tang","Staff, Section of Heart Failure and Cardiac Transplantation Medicine & Staff, Cleveland Clinic Research","100642184","dietary-tracking-in-heart-failure-100642184",false,"NCT07649148","Dietary Tracking in Heart Failure","Dietary Optimization Through Tracking and Integrated Evaluation","DOTTIE","Inclusion Criteria:\n\n* Adults (≥18 years) with NYHA Class II-III HF\n* Able to use Cronometer to track dietary intake and able to prepare food at home independently (able to modify dietary intake)\n\nExclusion Criteria:\n\n* History of heart transplant or LVAD implant\n* Unable or unwilling to follow dietary coaching for UPF reduction\n* eGFR \\\u003C30 ml\u002Fkg\u002F1.73m2","ALL","18 Years",{"count":60,"type":61},60,"ESTIMATED","OBSERVATIONAL","Emerging evidence links ultra processed foods (UPFs) to adverse cardiovascular outcomes. UPFs are often high in sodium, unhealthy fats and added sugars, while being low in essential nutrients and fiber. UPFs contribute to systemic inflammation, fluid retention, and metabolic dysfunction-key drivers of HF and kidney disease progression. Traditional dietary counseling often lacks specificity around food processing levels. Furthermore, the majority of nutrition studies relied on extensive self-reported dietary recall food frequency questionnaires (FFQ) that are subjective, often labor intensive, and difficult to implement practically in the clinical setting. As such, researchers have developed metabolite scores from blood and urine samples to help quantify UPF consumption, which has the promise to better guide dietary counseling and track process. Therefore, the aim of this study is to evaluate the feasibility and physiological impact of a structured UPF-reduction dietary intervention in patients with HF, leveraging both digital dietary tools (Cronometer) and biomarker assessments.",[65,66,67],"Heart Failure","NYHA Class II Heart Failure","NYHA Class III Heart Failure",[69,70,65,71,72],"Diet Tracking","Diet","Cronometer","Ultra Processed Food","2026-06-15",{"date":75,"type":76},"2026-06-17","ACTUAL",{"date":78,"type":61},"2026-06",{"date":80,"type":61},"2040-06",{"name":5,"class":6},1]