[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595519":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":10,"maxAge":10,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Mansoura University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"BI-RADS 4 breast lesions",null,"evaluate the reliability of ADC and micro calcifications (when present) in combination with the Kaiser score in improving the accuracy of the evaluation of BI- RADS 4 lesions and helping avoidance of unnecessary biopsies.",[13],"Diagnostic Test: MRI diffusion coefficient and micro-calcifications to Kaiser Score in evaluation of BI-RADS 4 breast lesions",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","MRI diffusion coefficient and micro-calcifications to Kaiser Score in evaluation of BI-RADS 4 breast lesions","Compare MRI diffusion coefficient and micro-calcifications to Kaiser Score in evaluation of BI-RADS 4 breast lesions",[9],[21],{"name":22,"affiliation":23,"role":24},"Mohamed AbdElmoniem","Lecturer of faculty of medicine Mansoura university","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","01014008473","dr.m1993@mans.edu.eg",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Maryam Hamdy foaud","01016881450","Maryamhamdy@mans.edu.eg",[35],{"facility":22,"status":36,"city":37,"state":10,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Al Mansurah","35516","Egypt","EG",{"type":42,"coordinates":43},"Point",[44,45],31.38069,31.03637,{"lat":45,"lon":44},[48,49],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":50,"role":51,"phone":10,"phoneExt":10,"email":10},"Maryam Hamdy foaud, lecturer","SUB_INVESTIGATOR",{"type":24,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mohamed Abd Elmoniem Mohamed","Lecturer faculty of medicine","100595519","diffusion-coefficient-and-micro-calcifications-to-kaiser-score-in-evaluation-of-bi-rads-4-breast-lesions-100595519",false,"NCT07033507","Diffusion Coefficient and Micro-calcifications to Kaiser Score in Evaluation of BI-RADS 4 Breast Lesions","Diagnostic Performance of Combining Apparent Diffusion Coefficient and Micro-calcifications to Kaiser Score in Evaluation of BI-RADS 4 Breast Lesions","Inclusion Criteria:\n\n* Patients with BI-RADS 4 lesion.\n\nExclusion Criteria:\n\n* Patients on chemotherapy or related treatment.\n* Patients who have contraindications to do MRI as patients with cardiac pace maker, patients with cochlear implant and ocular foreign body, claustrophobia.","FEMALE",{"count":64,"type":65},80,"ESTIMATED","OBSERVATIONAL","Breast cancer is the most commonly diagnosed cancer worldwide and is the leading cause of cancer-related deaths in women. Mammography, breast ultrasonography (US), and breast magnetic resonance imaging (MRI) are essential for the diagnosis and follow-up of breast cancer. The American College of Radiology Breast Imaging- Reporting and Data System (ACR BI-RADS), which is used worldwide, provides the standard terminology for breast imaging (Jajodia et al., 2021). The ACR BI- RADS lexicon categorizes breast imaging findings into seven BIRADS categories of 0, 1, 2, 3, 4(4a, 4b, 4c), 5, and 6 according to the probability of malignancy. Breast imaging findings assigned as BI-RADS 4 require tissue sampling and histopathological examination. However, the likelihood of malignancy of lesions classified as BI-RADS 4 ranges widely, from 3% to 94%. Categorization of lesions according to BI-RADS is related to the experience of the radiologist, with experienced radiologists performing better than inexperienced radiologists",[69],"Breast Neoplasms",[9,71,72,73],"diffusion coefficient","micro-calcifications","Kaiser Score","2025-06-14",{"date":76,"type":77},"2025-06-24","ACTUAL",{"date":79,"type":77},"2024-06-01",{"date":81,"type":65},"2026-01-01",{"name":5,"class":6},1]