[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601301":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":41,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"The General Authority for Teaching Hospitals and Institutes","NETWORK",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group",null,"Patients diagnosed with suspected early-stage white matter disease (e.g., multiple sclerosis, small vessel disease, Alzheimer's disease, frontotemporal dementia, leukoaraiosis) will be enrolled.",[13],"Other: Magnetic Resonance Imaging (MRI)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"OTHER","Magnetic Resonance Imaging (MRI)","Magnetic Resonance Imaging (MRI) Scanner: All imaging will be performed using a 1.5 tesla MRI scanner to ensure high resolution and signal-to-noise ratio.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Hekmat S Baumey, MD","CONTACT","00201555433546","hekmattsamir@gmail.com",[27],{"facility":28,"status":29,"city":30,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"General Authority for Teaching Hospitals and Institutes","RECRUITING","Cairo","Egypt","EG",{"type":34,"coordinates":35},"Point",[36,37],31.24967,30.06263,{"lat":37,"lon":36},[40],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hekmat Samir Baumey","Lecturer of Diagnostic Radiology, Damnhour National Medical Institute","100601301","diffusion-magnetic-resonance-imaging-dmri-in-the-early-evaluation-of-brain-white-matter-diseases-100601301",false,"NCT07108712","Diffusion Magnetic Resonance Imaging (dMRI) in the Early Evaluation of Brain White Matter Diseases","The Role of Diffusion Magnetic Resonance Imaging (dMRI) in the Early Evaluation of Brain White Matter Diseases","Inclusion Criteria:\n\n* Adults aged 18-80 years.\n* Clinical suspicion of early-stage white matter disease.\n* No prior diagnosis of significant neurological disorders (e.g., stroke, brain tumors).\n* Ability to provide informed consent.\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding.\n* Contraindications for magnetic resonance imaging (MRI) (e.g., metal implants, pacemakers).\n* Severe psychiatric or cognitive impairment that prevents participation.\n* Control Group: Healthy individuals without any clinical history of neurological diseases, matched by age and sex to the patient cohort.","ALL","18 Years","80 Years",{"count":56,"type":57},150,"ESTIMATED","OBSERVATIONAL","To assess the sensitivity and accuracy of diffusion magnetic resonance imaging (MRI), including diffusion-weighted imaging (DWI) metrics, in identifying early-stage changes in brain white matter related to various white matter diseases.",[61,62],"Diffusion Magnetic Resonance Imaging","Brain White Matter Diseases","2025-07-31",{"date":65,"type":66},"2025-08-07","ACTUAL",{"date":68,"type":66},"2025-05-01",{"date":70,"type":57},"2025-12-01",{"name":5,"class":6},1]