[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100527002":3},{"organization":4,"armGroups":7,"interventions":48,"overallOfficials":54,"centralContacts":71,"locations":81,"responsibleParty":97,"collaborators":54,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":101,"sex":107,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":54,"studyType":113,"phases":114,"briefSummary":116,"conditions":117,"keywords":119,"overallStatus":84,"whyStopped":54,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":132},{"fullName":5,"class":6},"Örebro University, Sweden","OTHER",[8,18,21,24,27,30,33,36,39,42,45],{"label":9,"type":10,"description":11,"interventionNames":12},"Dietary Intervention Sequence 1 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))","EXPERIMENTAL","The participant will consume the below mentioned meals in a random order on five different study days (one on each visit):\n\n* Protein meal: pea protein, low bioavailability\n* Protein meal: pea protein, high bioavailability\n* Protein meal: oat protein, low bioavailability\n* Protein meal: oat protein, high bioavailability\n* Protein-free meal",[13,14,15,16,17],"Dietary Supplement: Oat Protein, low bioavailability","Dietary Supplement: Oat Protein, high bioavailability","Dietary Supplement: Pea Protein, low bioavailability","Dietary Supplement: Pea Protein, high bioavailability","Dietary Supplement: Protein-free meal",{"label":19,"type":10,"description":11,"interventionNames":20},"Dietary Intervention Sequence 2 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":22,"type":10,"description":11,"interventionNames":23},"Dietary Intervention Sequence 3 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":25,"type":10,"description":11,"interventionNames":26},"Dietary Intervention Sequence 4 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":28,"type":10,"description":11,"interventionNames":29},"Dietary Intervention Sequence 5 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":31,"type":10,"description":11,"interventionNames":32},"Dietary Intervention Sequence 6 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":34,"type":10,"description":11,"interventionNames":35},"Dietary Intervention Sequence 7 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":37,"type":10,"description":11,"interventionNames":38},"Dietary Intervention Sequence 8 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":40,"type":10,"description":11,"interventionNames":41},"Dietary Intervention Sequence 9 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":43,"type":10,"description":11,"interventionNames":44},"Dietary Intervention Sequence 10 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],{"label":46,"type":10,"description":11,"interventionNames":47},"Dietary Intervention Sequence 11 (Meals: Pea protein (2x), Oat protein (2x), Protein-free (1x))",[13,14,15,16,17],[49,55,59,63,67],{"type":50,"name":51,"description":52,"armGroupLabels":53,"otherNames":54},"DIETARY_SUPPLEMENT","Oat Protein, low bioavailability","Participants will consume a protein meal consisting of cooked whole oat kernels (amount based on body weight, 0.3g of protein\u002Fkg bodyweight).",[9,43,46,19,22,25,28,31,34,37,40],null,{"type":50,"name":56,"description":57,"armGroupLabels":58,"otherNames":54},"Oat Protein, high bioavailability","Participants will consume a protein meal consisting of heated oat protein concentrate (amount based on body weight, 0.3g of protein\u002Fkg bodyweight).",[9,43,46,19,22,25,28,31,34,37,40],{"type":50,"name":60,"description":61,"armGroupLabels":62,"otherNames":54},"Pea Protein, low bioavailability","Participants will consume a protein meal consisting of cooked whole yellow peas (amount based on body weight, 0.3g of protein\u002Fkg bodyweight).",[9,43,46,19,22,25,28,31,34,37,40],{"type":50,"name":64,"description":65,"armGroupLabels":66,"otherNames":54},"Pea Protein, high bioavailability","Participants will consume a protein meal consisting of heated pea protein isolate (amount based on body weight, 0.3g of protein\u002Fkg bodyweight).",[9,43,46,19,22,25,28,31,34,37,40],{"type":50,"name":68,"description":69,"armGroupLabels":70,"otherNames":54},"Protein-free meal","Participants will consume a protein-free meal to correct analyses for endogenous protein losses.",[9,43,46,19,22,25,28,31,34,37,40],[72,77],{"name":73,"role":74,"phone":75,"phoneExt":54,"email":76},"Robert Brummer, PhD","CONTACT","004619303731","robert.brummer@oru.se",{"name":78,"role":74,"phone":79,"phoneExt":54,"email":80},"Annalena Kamm, MSc","0046790676822","annalena.kamm@oru.se",[82],{"facility":83,"status":84,"city":85,"state":54,"zip":86,"country":87,"countryCode":88,"cosmosGeoPoint":89,"geoPoint":94,"contacts":95},"Örebro University","RECRUITING","Örebro","70182","Sweden","SE",{"type":90,"coordinates":91},"Point",[92,93],15.2066,59.27412,{"lat":93,"lon":92},[96],{"name":73,"role":74,"phone":75,"phoneExt":54,"email":76},{"type":98,"investigatorFullName":54,"investigatorTitle":54,"investigatorAffiliation":54,"oldNameTitle":54,"oldOrganization":54},"SPONSOR","100527002","digestibility-of-different-plant-based-proteins-in-humans-with-ileostomy-100527002",false,"NCT06142084","Digestibility of Different Plant-based Proteins in Humans With Ileostomy","True Ileal Digestibility of Different Plant-based Proteins in a Human Ileostomy Model","PAN-Prodig","Inclusion Criteria:\n\n* Age: 18 - 75 years\n* Body mass index: 18.5 - 30 kg\u002Fm2\n* (double-loop) Ileostomy with an intact small bowel\n* Signed informed consent\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Ileostomy \\\u003C 3 months before the study\n* Any clinically significant present or past disease\u002Fcondition other than colon cancer which in the investigator's opinion could interfere with the results of the trial\n* Any clinically significant present or past medication which in the investigator's opinion could interfere with the results of the trial","ALL","18 Years","75 Years",{"count":111,"type":112},11,"ESTIMATED","INTERVENTIONAL",[115],"NA","The goal of this interventional study is to learn about the digestibility of different plant-based proteins in adults (age 18-75) with an ileostomy.\n\nThe main questions the study aims to answer are:\n\n1. How does the digestibility of proteins in the small intestine differ between different plant-based proteins?\n2. Which proteins and amino acids are not digested or absorbed in the small intestine and are available for further metabolic processes in the large intestine?\n3. How do metabolites in the collected content of the ileostomy bag differ after consuming different plant-based proteins?\n4. Can the in vivo results be compared to results from existing in vitro models?\n\nParticipants will consume five different protein meals (oat protein - high bioavailable, oat protein - low bioavailable, pea protein - high bioavailable, pea protein low bioavailable, protein-free meal) on five different study days in a random order. Five hours after consuming the test meals ileostomy bags will be collected and the content will be analysed to answer the above mentioned research questions.",[118],"Ileostomy - Stoma",[120,121,122],"Protein","Plant-based","Digestibility","2026-06-22",{"date":125,"type":126},"2026-06-23","ACTUAL",{"date":128,"type":112},"2026-09",{"date":130,"type":112},"2028-12",{"name":5,"class":6},1]