[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614993":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":37,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":10,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":10,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"First Hospital of China Medical University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cognitive impairment group",null,"The subjects diagnosed with AD-related cognitive impairment through early screening of cognitive disorders and examination of AD blood markers",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy population group","The subjects who were diagnosed as negative through early screening for cognitive impairment and examination of AD blood markers",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Huayan Liu, PhD.","CONTACT","+86 13609831417","liuhy@cmu1h.com",[22],{"facility":23,"status":10,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"The First Affiliated Hospital of China Medical University","Shenyang","Liaoning","110001","China","CN",{"type":30,"coordinates":31},"Point",[32,33],123.43278,41.79222,{"lat":33,"lon":32},[36],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Liu Huayan","Neurology department","100614993","digital-technology-combined-with-blood-marker-screening-and-diagnosis-for-community-populations-based-on-classification-theory-an-integrated-study-100614993",false,"NCT07286812","Digital Technology Combined With Blood Marker Screening and Diagnosis for Community Populations Based on Classification Theory: an Integrated Study","Inclusion Criteria:\n\n1. Adults aged 50 and above;\n2. Residents of this community for at least one year, with established medical records;\n3. Deny a history of cognitive impairment diseases (mild cognitive impairment, dementia, Alzheimer's, etc.) and the use of anti-dementia drugs (cholinesterase inhibitors or memantine, etc.);\n4. Agree to participate in the study;\n5. The individual and their relatives can communicate normally in Chinese.\n\nExclusion Criteria:\n\n1. Self-reported or confirmed through inquiry that there is a severe mental disorder, such as bipolar disorder or schizophrenia, etc.\n2. Suffering from a disease that makes it impossible to complete the cognitive assessment.",true,"ALL","50 Years",{"count":51,"type":52},1000,"ESTIMATED","OBSERVATIONAL","Our research hypothesis is as follows: A step - by - step screening strategy based on screening technologies can resolve the issue of insufficient efficiency in the traditional scale - based screening model. Meanwhile, performing pathological diagnoses on patients with suspected cognitive impairment identified through screening is conducive to the further implementation of etiology - based treatment and intervention, thus bringing benefits to patients at the earliest possible stage.\n\nBy exploring the characteristic changes in gait, facial expressions, and language of patients with suspected cognitive impairment and analyzing their diagnostic efficiency for cognitive impairment patients, new ideas can be provided for the early diagnosis of the disease.\n\nThrough longitudinal observation of the changes in disease - related information during the progression and transformation of the disease, a predictive model for the early diagnosis of cognitive impairment and the prediction of disease progression can be constructed.",[56],"Alzheimer Disease","NOT_YET_RECRUITING","2025-12-13",{"date":60,"type":61},"2025-12-16","ACTUAL",{"date":63,"type":52},"2025-12-25",{"date":65,"type":52},"2026-07-31",{"name":5,"class":6},1]