[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610829":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":42,"locations":51,"responsibleParty":72,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":10,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":10,"enrollmentInfo":90,"targetDuration":93,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":54,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"China Medical University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Health Promotion through Wearable and Mobile Technology",null,"Participants will join a community-based health program integrating wearables, mobile health platforms, and structured education to promote active lifestyles, enhance health literacy, and collect longitudinal data in older adults in rural Taiwan.\n\nParticipants will:\n\n1. Wear a research-grade wrist actigraphy device (GeneActiv) to record activity, sleep, and light exposure for ≥2 weeks.\n2. Use the iMED mobile app (NHRI, Taiwan) for feedback, health education, and medication tracking.\n3. For participants with limited mobility, use an under-mattress iCue sensor to monitor respiration and movement.\n4. Attend Aging Well Taiwan sessions based on the WHO ICOPE framework.\n5. Provide baseline and follow-up blood samples for dementia-related biomarkers (Tau, Aβ, NfL) and APOE genotyping.",[13,14,15,16,17],"Device: Geneactiv","Behavioral: iMED Mobile Health Platform","Device: iCue","Behavioral: Aging Well Taiwan","Biological: Blood Biomarker Sampling",[19,24,29,33,37],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DEVICE","Geneactiv","Participants will wear a research-grade actigraphy device (Geneactiv original, developed by Activinsights UK) on the non-dominant wrist for at least two consecutive weeks to continuously record physical activity, sleep-wake patterns, and light exposure. The visualised results will be presented to the participants to motivate their behavioural change.",[9],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"BEHAVIORAL","iMED Mobile Health Platform","Participants will use the \"iMED\" mobile application developed by the National Health Research Institutes in Taiwan (https:\u002F\u002Fwww.nhri.imed-health.com\u002F). The platform provides personalized health education, medication reminders, AI-driven feedback on wearable data, and links to Taiwan's National Health Insurance health records.",[9],{"type":20,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"iCue","A non-invasive smart mat (iCue) placed under the mattress continuously monitors respiration rate, movement, and sleep parameters in participants with limited mobility.",[9],{"type":25,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Aging Well Taiwan","Participants will attend a community-based educational course adapted from Singapore's \"Aging Well\" framework, covering physical activity, diet, cognitive health, and digital literacy. The program follows the WHO Integrated Care for Older People (ICOPE) model and supports active aging and social participation.",[9],{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":10},"BIOLOGICAL","Blood Biomarker Sampling","Participants will provide venous blood samples at baseline and follow-up visits for analysis of dementia-related biomarkers, including total Tau, phosphorylated Tau 181 (pT181), phosphorylated Tau 217 (pT217), amyloid beta 1-40 (Aβ40), amyloid beta 1-42 (Aβ42), and neurofilament light chain (NfL), as well as apolipoprotein E (APOE) genotyping.",[9],[43,48],{"name":44,"role":45,"phone":46,"phoneExt":10,"email":47},"Dr Ta-Wei Guu Consultant psychiatrist, MD, PhD","CONTACT","+886-57837901","066753@tool.caaumed.org.tw",{"name":49,"role":45,"phone":10,"phoneExt":10,"email":50},"Yueh-Heng Chiang, RN, MS.","isyuehheng@gmail.com",[52],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"China Medical University Beigang Hospital","RECRUITING","London","Alabama","WC1N 2AN","United Kingdom","UK",{"type":61,"coordinates":62},"Point",[63,64],-0.12574,51.50853,{"lat":64,"lon":63},[67,70],{"name":68,"role":45,"phone":46,"phoneExt":10,"email":69},"Ta-Wei Guu, MD, PhD","da20vid@gmail.com",{"name":71,"role":45,"phone":46,"phoneExt":10,"email":50},"Yueh-Heng Chiang, RN, MS",{"type":73,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ta-wei Guu","Consultant Psychiatrist",[77],{"name":78,"class":79},"Ministry of Health and Welfare, Taiwan","OTHER_GOV","100610829","digital-technology-for-active-and-healthy-ageing-in-taiwan-100610829",false,"NCT07232667","Digital Technology for Active and Healthy Ageing in Taiwan","Healthy Taiwan Cultivation Plan: Building an Active-ageing Lifestyle in Rural Taiwan Through Integrating Novel Healthcare Technology - From Mitigating Digital and Health Literacy Gap, Establishing a Mobile Interactive Pro-active-ageing Information Platform, to Exploring Multi-dimensional Digital Biomarkers of Ageing","Inclusion Criteria:\n\n1. Currently living or receiving care in a stable environment for at least four weeks prior to enrollment:\n\n   * For community-based participants: must have resided at the same address for ≥4 weeks.\n   * For day-care participants: must have attended activities at the same dementia or elderly day-care center for ≥4 weeks.\n2. Able and willing to participate in the study procedures.\n3. Informed consent must be obtained before participation.\n\n   * If the participant's cognitive function has declined to a level that prevents self-consent, written consent will be obtained from a legally authorized representative or primary caregiver.\n\nExclusion Criteria:\n\n1. Unstable physical or psychological condition that makes participation unsafe, as determined by a clinical investigator - e.g., acute delirium or current respiratory infection (including COVID-19).\n2. Any known allergy or skin sensitivity to the materials used in the Geneactiv actigraphy device or iCue sensor pad.\n3. Any other medical, neurological, or behavioral condition deemed unsuitable for participation by the study physician.",true,"ALL","60 Years",{"count":91,"type":92},140,"ESTIMATED","2 Weeks","OBSERVATIONAL","Taiwan is entering a super-aged society in 2025, with more than 20% of the population aged 65 years or older. This rapid demographic shift, combined with increasing rates of chronic diseases, frailty, and dementia, has created growing challenges for healthcare and caregiving systems. Yunlin County, particularly its coastal region, has been one of Taiwan's earliest super-aged areas, showing higher rates of diabetes (10.5%), hypertension (28%), hyperlipidemia (26%), dementia (8%), and depression (12%) compared with national averages. Lifestyle factors such as tobacco (30%), betel nut (8%), and alcohol (15%) use are also more prevalent among local residents.\n\nFrom 2022 to 2024, health screenings at CMU Beigang Hospital revealed a 36.1% abnormality rate among 12,222 visits, while another 5,965 assessments from the county's ICOPE program showed similarly high rates. Many older adults, particularly retired agricultural and fishing workers, experience sedentary lifestyles and polypharmacy-related risks, which worsen frailty, insomnia, depression, and cognitive decline. Low general and digital health literacy further limits their ability to adopt preventive behaviors, forming a vicious cycle between poor health and aging.\n\nTo address these challenges, the Ministry of Health and Welfare launched the \"Healthy Taiwan Cultivation Plan.\" In alignment with this initiative, this project-led by CMU Beigang Hospital in collaboration with the National Health Research Institutes-aims to develop a wearable- and mobile-based health promotion model for rural older adults. The study will integrate research-grade actigraphy (Geneactiv), a mobile health platform (\"iMED\"), and the in-bed sensor iCue to monitor behavior, promote active aging, and enhance health and digital literacy. Ultimately, this project seeks to establish Taiwan's first integrated digital aging database and identify digital biomarkers for predicting cognitive and functional decline in older adults.",[97,98],"Healthy Aging","Digital Health Literacy",[100,101,102,103,104,105,106],"Elderly people","Wearable technology","Digital health literacy","Healthy aging","Health literacy","Digital gap","Digital biomarkers","2026-05-15",{"date":109,"type":110},"2026-05-18","ACTUAL",{"date":112,"type":110},"2026-04-22",{"date":114,"type":92},"2029-12-31",{"name":5,"class":6},1]