[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499449":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":48,"responsibleParty":77,"collaborators":10,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":10,"enrollmentInfo":89,"targetDuration":10,"studyType":92,"phases":10,"briefSummary":93,"conditions":94,"keywords":97,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort A: palliative care center",null,"Patients from a palliative care center (Palliativzentrum Hildegard, Basel)",[13,14,15],"Other: Data acquisition: Speech acquisition","Diagnostic Test: Data acquisition: G8 Screening tool","Diagnostic Test: Data acquisition: Distress Thermometer",{"label":17,"type":10,"description":18,"interventionNames":19},"Cohort B: mid-size cancer center","Patients from a mid-size cancer center (Tumorzentrum Baselland)",[13,14,15],[21,25,30],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Data acquisition: Speech acquisition","Speech test with synchronized audio and video recording. The speaking exercises and the audio and video recording will be done using a tablet computer and an application developed in-house. Freely available images showing different scenes will be integrated and displayed on the tablet to be described by the patient. The goal is to have at least two and maximum four of them described with several sentences by each patient per session. Parameters will be extracted from the patient's audio data to estimate the changes in distress and frailty.",[9,17],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"DIAGNOSTIC_TEST","Data acquisition: G8 Screening tool","The G8 screening tool consists of seven items dealing with food intake, weight loss, mobility, neuropsychological problem, body mass index, prescription drug, and self-perception of health, from the Mini-Nutritional Assessment (MNA) questionnaire and was developed specifically for elderly cancer patients. The total G-8 score lies between 0 and 17. A higher score indicates a better health status.",[9,17],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Data acquisition: Distress Thermometer","The distress thermometer (DT) is a measure of psychological distress in cancer patients. The instrument is a self-reported tool using a 0-to-10 rating scale.",[9,17],[35],{"name":36,"affiliation":37,"role":38},"Marcus Vetter, PD Dr. med.","Kantonsspital Baselland, Klinik für Onkologie, Hämatologie und Immuntherapie","PRINCIPAL_INVESTIGATOR",[40,44],{"name":36,"role":41,"phone":42,"phoneExt":10,"email":43},"CONTACT","+41 61 925 2525","marcus.vetter@ksbl.ch",{"name":45,"role":41,"phone":46,"phoneExt":10,"email":47},"Jan Gärtner, Prof. Dr. med.","+41 61 319 7575","jan.gaertner@pzhi.ch",[49,65],{"facility":50,"status":51,"city":52,"state":10,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Palliativzentrum Hildegard, Basel","RECRUITING","Basel","4002","Switzerland","CH",{"type":57,"coordinates":58},"Point",[59,60],7.57327,47.55839,{"lat":60,"lon":59},[63,64],{"name":45,"role":41,"phone":46,"phoneExt":10,"email":47},{"name":45,"role":38,"phone":10,"phoneExt":10,"email":10},{"facility":37,"status":51,"city":66,"state":10,"zip":67,"country":54,"countryCode":55,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Liestal","4410",{"type":57,"coordinates":69},[70,71],7.73446,47.48455,{"lat":71,"lon":70},[74,76],{"name":36,"role":41,"phone":75,"phoneExt":10,"email":43},"+ 41 61 925 2525",{"name":36,"role":38,"phone":10,"phoneExt":10,"email":10},{"type":78,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100499449","digital-voice-analysis-as-a-measure-of-frailty-and-distress-100499449",false,"NCT05783401","Digital Voice Analysis as a Measure of Frailty and Distress","Digital Voice Analysis as a Measure of Frailty and Distress. A Feasibility Study (DIVAN)","DIVAN","Inclusion Criteria:\n\n* Active cancer or haemato-oncological malignancy\n* Adults (≥ 18 years)\n* Ability to understand, speak and read German language fluently\n* Ability to provide written consent\n* Sufficient or corrected vision to see the images\n* Sufficient auditory comprehension for participation in the study based on the therapist's clinical opinion\n* Ability to concentrate for 20-30 minutes based on the investigator's clinical opinion\n* Signed informed consent to the study\n\nExclusion Criteria:\n\n* Aphonia, dysphonia or other obvious voice alterations of patient's voice\n* Life-expectancy shorter ≤ 14 days as judged by a physician or nurse via \"surprise question\"\n* Breathlessness whilst speaking\n* Cognitive impairment as judged by physician or Mini-Cog in the G8 screening tool\n* Severe physical, emotional or existential suffering because of which the enrollment and participation in the study would result in patient burden, as judged by the treating physicians and their multiprofessional team members","ALL","18 Years",{"count":90,"type":91},100,"ESTIMATED","OBSERVATIONAL","This study evaluates if it is possible to identify quantitative parameters from audio signals to describe the changes in patient's state in relation to frailty and distress.",[95,96],"Frailty","Distress, Emotional",[98,99,100,101,102,103],"Frailty monitoring","Distress monitoring","Digital voice analysis (DVA)","Machine learning","Distress Thermometer","G8 geriatric screening tool","2025-01-16",{"date":106,"type":107},"2025-01-17","ACTUAL",{"date":109,"type":107},"2022-11-19",{"date":111,"type":91},"2025-11",{"name":5,"class":6},2]