[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639644":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":37,"locations":47,"responsibleParty":76,"collaborators":78,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":85,"sex":91,"minAge":92,"maxAge":41,"enrollmentInfo":93,"targetDuration":41,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":111,"whyStopped":41,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Ludwig Boltzmann Institute for Digital Health and Prevention","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Usual care","Usual Care (Control). Participants receive standard preoperative, surgical, and postoperative care including standard inpatient rehabilitation without prehabilitation or digital support.",[12],"Other: Usual Care Group",{"label":14,"type":15,"description":16,"interventionNames":17},"Multimodal Video-Supported Prehabilitation","EXPERIMENTAL","Multimodal Video-Supported Prehabilitation plus Digitally Supported Transition. Participants receive a 10 to 14-day multimodal prehabilitation program including endurance, resistance, coordination, and gait training, supported by the aktivplan application, one teleconsultation via CAATS, and research sensors for documentation. Digital support continues during the early post-discharge transition phase with low-threshold exercises and educational content until inpatient rehabilitation begins.",[18],"Behavioral: EXERCISE TRAINING WITH OR WITHOUT MEDICATION",[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","EXERCISE TRAINING WITH OR WITHOUT MEDICATION","A short-term multimodal, video-supported prehabilitation program delivered over 10 to 14 days before surgery, including endurance, resistance, coordination, and gait training with crutches. The intervention is introduced during an in-person session and subsequently performed at home using a digital application to provide structured exercise guidance and support adherence. A single teleconsultation is conducted to ensure safety, provide feedback, and allow individualized progression. In addition, digital support is extended into the early post-discharge transition phase, providing low-threshold exercise guidance and educational content to support mobility, self-efficacy, and continuity of care until the start of inpatient rehabilitation.",[14],[26],"Multimodal Prehabilitation Program",{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Usual Care Group","Participants allocated to the usual care group will receive the standard perioperative treatment provided at the study site. This includes preoperative consultation, elective total knee replacement surgery according to institutional standards, and routine postoperative care. After hospital discharge, participants return home until the start of standardized inpatient rehabilitation (Phase II), including interdisciplinary care such as physiotherapy, occupational therapy, medical supervision, and health education. No structured prehabilitation or digitally supported intervention will be provided.",[9],[32],"Usual Care Control Group",[34],{"name":35,"affiliation":5,"role":36},"Daniela Wurhofer, Dr.","STUDY_DIRECTOR",[38,43],{"name":35,"role":39,"phone":40,"phoneExt":41,"email":42},"CONTACT","+43 (0) 57 255 82702",null,"daniela.wurhofer@lbg.ac.at",{"name":44,"role":39,"phone":45,"phoneExt":41,"email":46},"Gunnar Treff, Univ.-Prof. Dr.","+43 5 7255 82711","gunnar.treff@pmu.ac.at",[48],{"facility":49,"status":41,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Medizinisches Zentrum Bad Vigaun GmbH & Co. KG","Hallein","State of Salzburg","5424","Austria","AT",{"type":56,"coordinates":57},"Point",[58,59],13.1,47.68333,{"lat":59,"lon":58},[62,66,70,72,74],{"name":63,"role":39,"phone":64,"phoneExt":41,"email":65},"Josef Sturm, Dr.","+43 650 2040605","josef.sturm@badvigaun.com",{"name":67,"role":39,"phone":68,"phoneExt":41,"email":69},"Hildebert Hutt, Prim. Dr.","+43 6245 8999 673","hildebert.hutt@badvigaun.com",{"name":67,"role":71,"phone":41,"phoneExt":41,"email":41},"PRINCIPAL_INVESTIGATOR",{"name":73,"role":71,"phone":41,"phoneExt":41,"email":41},"Thomas Hofstädter, Prim. Dr.",{"name":63,"role":75,"phone":41,"phoneExt":41,"email":41},"SUB_INVESTIGATOR",{"type":77,"investigatorFullName":41,"investigatorTitle":41,"investigatorAffiliation":41,"oldNameTitle":41,"oldOrganization":41},"SPONSOR",[79,81],{"name":80,"class":6},"Paracelsus Medical University",{"name":82,"class":6},"Medizinische Zentrum Bad Vigaun GmbH & Co. KG","100639644","digitally-supported-short-term-prehabilitation-before-total-knee-replacement-100639644",false,"NCT07621666","Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement","Prehab2Rehab: Digitally Supported Short-Term Prehabilitation Before Total Knee Replacement - A Randomized Controlled Feasibility Trial","P2R-KneeTEP","Inclusion Criteria:\n\nEligibility will be determined during the outpatient consultations at the Medical\n\nCenter in Bad Vigaun. Patients will be screened against the following criteria:\n\n* Age ≥18 years at the time of enrolment.\n* Clinically diagnosed with advanced osteoarthritis and with a medical indication for elective TKR.\n* Either a scheduled surgery or a documented intention to undergo TKR within the recruitment period.\n* Elective surgery is scheduled for at least 14 days after enrolment to allow completion of the 10 to 14-day prehabilitation intervention.\n* Physical ability to safely perform the prescribed exercise program, as confirmed by the treating physician.\n* Willingness to participate in a digitally supported training intervention at either the center or home-based.\n* Sufficient digital literacy and access to internet-enabled devices (smartphone, tablet, or computer).\n* Adequate German language proficiency to follow exercise instructions and study procedures.\n\nExclusion Criteria:\n\nPatients will be excluded if any of the following apply:\n\n* Pregnancy at the time of enrolment.\n* Emergency, revisional, or non-elective surgery.\n* Surgery scheduled less than 14 days after enrolment.\n* Severe physical impairment or medical contraindication to exercise training (e.g., unstable cardiovascular disease, uncontrolled hypertension, acute musculoskeletal injury).\n* Patients with contraindications outlined in the Medizinisches Leistungsprofil (MLP) 2.0 that preclude rehabilitation and\u002For surgery.\n* Participation in another clinical study that could interfere with the intervention or study outcomes.","ALL","18 Years",{"count":94,"type":95},60,"ESTIMATED","INTERVENTIONAL",[98],"NA","This study evaluates the feasibility of a short-term, digitally supported prehabilitation program for patients scheduled for elective total knee replacement (TKR). Osteoarthritis is a leading cause of disability, and recovery following TKR remains heterogeneous, with a substantial proportion of patients experiencing delayed functional recovery. Prehabilitation may improve perioperative outcomes, but its implementation is often limited by short preoperative time windows.\n\nThe Prehab2Rehab-KneeTEP trial is a single-center, two-arm, randomized controlled feasibility study conducted in Austria. Patients will be randomized (1:1) to either a multimodal video-supported prehabilitation program or usual care. The intervention consists of a 10 to 14-day preoperative exercise program including strength, endurance, coordination, and gait training, supported by a digital application, and is complemented by a digitally supported transition phase after hospital discharge until the start of inpatient rehabilitation.\n\nThe primary objective is to assess feasibility in terms of recruitment, retention, adherence, fidelity, acceptability, and safety. Secondary exploratory outcomes include clinical recovery indicators, functional performance, and patient-reported outcomes assessed across the perioperative pathway.",[101,102],"Knee Osteoarthristis","Total Knee Replacement",[104,105,106,107,108,109,110],"Prehabilitation","Digital Health","Exercise Therapy","Perioperative Care","Rehabilitation Pathway","Randomised Controlled Trial","Tele-rehabilitation","NOT_YET_RECRUITING","2026-06-02",{"date":114,"type":115},"2026-06-04","ACTUAL",{"date":117,"type":95},"2026-05-20",{"date":119,"type":95},"2027-05-01",{"name":5,"class":6},1]