[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633900":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":32,"locations":38,"responsibleParty":63,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":26,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":41,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Military Hospital 103","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"SRP + diode laser","EXPERIMENTAL","Participants receive full-mouth scaling and root planing combined with adjunctive diode laser treatment according to the study protocol.",[13,14],"Procedure: Scaling and Root Planing","Device: Diode Laser",{"label":16,"type":17,"description":18,"interventionNames":19},"SRP alone","ACTIVE_COMPARATOR","Participants receive full-mouth scaling and root planing alone according to the study protocol",[13],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Scaling and Root Planing","Conventional non-surgical periodontal therapy performed according to the study protocol in both groups.",[9,16],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"DEVICE","Diode Laser","Adjunctive diode laser application to periodontal pockets after SRP in the experimental arm. Device specifications, wavelength, power settings, mode, fiber size, number of applications, and treatment sessions should match the approved protocol exactly.",[9],[33],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},"Thang V Dinh, Principal Investigator","CONTACT","+84971349066","bsdinhthang277@gmail.com",[39,55],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"103 Military Hospital","RECRUITING","Hanoi","Hadong","100000","Vietnam","VN",{"type":48,"coordinates":49},"Point",[50,51],105.84117,21.0245,{"lat":51,"lon":50},[54],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},{"facility":56,"status":41,"city":42,"state":57,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":58,"geoPoint":60,"contacts":61},"Vietnam Military Medical University","QUẬN HÀ ĐÔNG",{"type":48,"coordinates":59},[50,51],{"lat":51,"lon":50},[62],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","VietThang Dinh","Principal Investigator","100633900","diode-laser-assisted-periodontal-therapy-in-kidney-transplant-recipients-100633900",false,"NCT07532694","Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients","Periodontal Status in Kidney Transplant Patients and the Effectiveness of Adjunctive Diode Laser Therapy","KTRs","Inclusion Criteria:\n\n* Kidney transplant recipients aged 18 years or older.\n* Diagnosis of periodontitis according to the study case definition.\n* Medically stable and able to undergo non-surgical periodontal treatment.\n* Willing and able to provide written informed consent and attend follow-up visits.\n\nExclusion Criteria:\n\n* \\- Periodontal treatment or systemic antibiotic use within the predefined exclusion window in the protocol.\n* Acute oral infection requiring urgent treatment.\n* Pregnancy or lactation, if excluded by the approved protocol.\n* Serious systemic condition or clinical instability judged by investigators to preclude study participation.\n* Inability to comply with study procedures or follow-up schedule.",true,"ALL",{"count":78,"type":79},80,"ESTIMATED","INTERVENTIONAL",[82],"NA","This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis. Eighty participants will be allocated to two parallel groups: scaling and root planing (SRP) with adjunctive diode laser therapy or SRP alone. Clinical periodontal parameters, blood biomarkers, radiographic findings, and subgingival microbiome profiles will be assessed at baseline and during follow-up. The study aims to determine whether adjunctive diode laser therapy provides superior clinical and biological improvement compared with SRP alone.",[85,86],"Periodontitis","Kidney Transplant Recipients",[88,89,90,91,92,93,94],"diode laser","scaling and root planing","periodontal therapy","kidney transplantation","16S rRNA","microbiome","C-reactive protein","2026-04-09",{"date":97,"type":98},"2026-04-16","ACTUAL",{"date":100,"type":98},"2025-12-09",{"date":102,"type":79},"2026-06-09",{"name":5,"class":6},2]